Maja Pušić
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View article: Growth Arrest-Specific Protein 6 Is Elevated in Endometriosis but Shows Poor Diagnostic Performance
Growth Arrest-Specific Protein 6 Is Elevated in Endometriosis but Shows Poor Diagnostic Performance Open
Growth arrest-specific protein 6 (GAS6) has an important role in regulating the immune system. Recent studies have revealed its association with the pathophysiology of endometriosis and identified GAS6 as one of the hub genes and a biomark…
View article: P-341 Identification of potential biomarkers for peritoneal endometriosis from the whole blood transcriptome by machine learning
P-341 Identification of potential biomarkers for peritoneal endometriosis from the whole blood transcriptome by machine learning Open
Study question Can blood biomarker candidates for peritoneal endometriosis be identified by an untargeted transcriptomic approach using whole genome RNA sequencing of whole blood and machine learning? Summary answer A machine learning feat…
View article: TGFBI as a candidate biomarker for non-invasive diagnosis of early-stage endometriosis
TGFBI as a candidate biomarker for non-invasive diagnosis of early-stage endometriosis Open
STUDY QUESTION Can cartilage oligomeric matrix protein (COMP) and transforming growth factor-β-induced protein ig-h3 (TGFBI) alone or in combination with cancer antigen 125 (CA-125) be considered as potential blood biomarkers of endometrio…
View article: Circulating estradiol and its biologically active metabolites in endometriosis and in relation to pain symptoms
Circulating estradiol and its biologically active metabolites in endometriosis and in relation to pain symptoms Open
Objectives Endometriosis (EM) is an estrogen-dominant inflammatory disease linked to infertility that affects women of reproductive age. EM lesions respond to hormonal signals that regulate uterine tissue growth and trigger inflammation an…
View article: Models including preoperative plasma levels of angiogenic factors, leptin and IL-8 as potential biomarkers of endometrial cancer
Models including preoperative plasma levels of angiogenic factors, leptin and IL-8 as potential biomarkers of endometrial cancer Open
Background The diversity of endometrial cancer (EC) dictates the need for precise early diagnosis and pre-operative stratification to select treatment options appropriately. Non-invasive biomarkers invaluably assist clinicians in managing …
View article: <i>In vitro</i> effects of ascorbic acid on viability and metabolism of patients’ osteosarcoma stem cells
<i>In vitro</i> effects of ascorbic acid on viability and metabolism of patients’ osteosarcoma stem cells Open
Stagnation in novelties of osteosarcoma (OS) treatment indicates the need for new therapeutic methods. OS cancer stem cells (OS-CSC) are taught to have the ability to self-renew and develop mechanisms of anticancer drug resistance, and thi…
View article: Antibody Arrays Identified Cycle-Dependent Plasma Biomarker Candidates of Peritoneal Endometriosis
Antibody Arrays Identified Cycle-Dependent Plasma Biomarker Candidates of Peritoneal Endometriosis Open
Endometriosis is an estrogen-dependent inflammatory disease affecting women in their reproductive age. Due to non-specific symptoms, women with endometriosis are often misdiagnosed or are accurately diagnosed only after several years. Diag…
View article: Morphological and Molecular Evaluation of the Tissue Repair following Nasal Septum Biopsy in a Sheep Model
Morphological and Molecular Evaluation of the Tissue Repair following Nasal Septum Biopsy in a Sheep Model Open
Objective Nasal septal pathologies requiring surgical intervention are common in the population. Additionally, nasal chondrocytes are becoming an important cell source in cartilage tissue engineering strategies for the repair of articular …
View article: Bioreactor‐manufactured cartilage grafts repair acute and chronic osteochondral defects in large animal studies
Bioreactor‐manufactured cartilage grafts repair acute and chronic osteochondral defects in large animal studies Open
Objectives Bioreactor‐based production systems have the potential to overcome limitations associated with conventional tissue engineering manufacturing methods, facilitating regulatory compliant and cost‐effective production of engineered …
View article: Bone Tissue Engineering in a Perfusion Bioreactor Using Dexamethasone-Loaded Peptide Hydrogel
Bone Tissue Engineering in a Perfusion Bioreactor Using Dexamethasone-Loaded Peptide Hydrogel Open
The main goal of this study was the formation of bone tissue using dexamethasone (DEX)-loaded [COCH3]-RADARADARADARADA-[CONH2] (RADA 16-I) scaffold that has the ability to release optimal DEX concentration under perfusion force. Bone-marro…
View article: PO-084 Ascorbic acid selectively targets glucose metabolism of osteosarcoma stem cells
PO-084 Ascorbic acid selectively targets glucose metabolism of osteosarcoma stem cells Open
Introduction Osteosarcoma (OS) is the most common primary bone sarcoma that mainly occurs in children and adolescents. The existence of drug resistant cancer stem cells (CSCs) with progenitor properties is responsible for OS relapse and m…