Majid Tafrihi
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View article: miR-151 in health and disease: A comprehensive review of its implications in Cancer, diabetes, and more
miR-151 in health and disease: A comprehensive review of its implications in Cancer, diabetes, and more Open
View article: The Pro-Apoptosis Induction of Teucrium persicum Ethyl Acetate Extract on MCF-7 Cells: An In Vitro Study
The Pro-Apoptosis Induction of Teucrium persicum Ethyl Acetate Extract on MCF-7 Cells: An In Vitro Study Open
Background: Teucrium persicum (T. persicum) is a well-known Iranian endemic plant that grows in the southern regions of Iran. It is used as a tea to treat abdominal pains, hyperlipidemia, and diabetes in traditional Iranian medicine. It ha…
View article: Exploring <i>in vitro</i> anticancer potential of <i>Ferula gummosa</i> gum on PC-3 cells: insights from cellular and molecular studies
Exploring <i>in vitro</i> anticancer potential of <i>Ferula gummosa</i> gum on PC-3 cells: insights from cellular and molecular studies Open
View article: Unveiling the Cytotoxic and Inhibitory Effects of <i>Ferula gummosa</i> Gum on A-375 Skin Cancer Cells: An in Vitro Study
Unveiling the Cytotoxic and Inhibitory Effects of <i>Ferula gummosa</i> Gum on A-375 Skin Cancer Cells: An in Vitro Study Open
Background: Ferula gummosa Boiss. is a widely recognized species native to Iran, primarily found in the northern and northeastern regions. It has long been valued for its medicinal properties, particularly in traditional medicine, where it…
View article: A small-scale test of whether alkalizing diets can reduce the risk of disease as predicted by the Warburg Hypothesis
A small-scale test of whether alkalizing diets can reduce the risk of disease as predicted by the Warburg Hypothesis Open
Diet and so-called dietary acid load have a significant effect on what have traditionally been called acid-base disorders and various disease states, including cancer. However, the effect has been poorly investigated, and standards of care…
View article: Understanding the Warburg Effect Yields New Insights into the Metabolic Control of Cancer
Understanding the Warburg Effect Yields New Insights into the Metabolic Control of Cancer Open
Human cells may use either aerobic or anaerobic cellular respiration processes to produce energy, depending on cellular conditions. When there is enough oxygen, cells respire aerobically, but in case of oxygen deficiency, anaerobic cellula…
View article: Improving Natural Resistance to Cancer: An Overview of Metabolic Pathways in Cancer Cells Integrated with Regional Cancer Incidence Statistics
Improving Natural Resistance to Cancer: An Overview of Metabolic Pathways in Cancer Cells Integrated with Regional Cancer Incidence Statistics Open
Context: Cellular metabolism is a set of controlled biochemical reactions known as metabolic pathways that occur in living organisms in order to sustain life. Cells may use different metabolic pathways and alter metabolism to use more effe…
View article: Association between PON1-rs662 Gene Polymorphism and Diabetic Retinopathy in Population of the Qom, Iran
Association between PON1-rs662 Gene Polymorphism and Diabetic Retinopathy in Population of the Qom, Iran Open
Background: Diabetic retinopathy is the most severe diabetic microvascular complication that causes changes in the vessel wall. One of the genes involved in this disease is PON1, which encodes paraoxanase1 protein in liver and kidney. It m…
View article: Global trends of cancer: The role of diet, lifestyle, and environmental factors
Global trends of cancer: The role of diet, lifestyle, and environmental factors Open
Effective treatment of cancer requires understanding the nature of the disease and accurately addressing the main root causes. General risk factors for cancer include poor nutrition, an acidogenic diet, an unhealthy lifestyle, and exposure…
View article: Antioxidant, cytotoxic, and genotoxic potentials of the gum of <i>Ferula gummosa</i> Boiss on PC-3 cells.
Antioxidant, cytotoxic, and genotoxic potentials of the gum of <i>Ferula gummosa</i> Boiss on PC-3 cells. Open
These results indicate that F. gummosa has considerable antioxidant and cytotoxic properties that can make it a good nominee for subsequent investigations.
View article: Gene Frequencies of Methylmalonic Acidemia Disease at the Global Level and Compiling the Pathogenic Mutations in the Iranian Population
Gene Frequencies of Methylmalonic Acidemia Disease at the Global Level and Compiling the Pathogenic Mutations in the Iranian Population Open
Background: Methylmalonic acidemia (MMA) is a rare autosomal recessive metabolic disorder resulting from a genetic defect in methylmalonyl-CoA mutase (MCM) or a defect in the biosynthesis of its cofactor, adenosyl-cobalamin (AdoCbl). The d…
View article: Effect of Aqueous Extract of Turkey Tail (Trametes versicolor) on Staphylococcus aureus, Escherichia coli and Fusarium thapsinum
Effect of Aqueous Extract of Turkey Tail (Trametes versicolor) on Staphylococcus aureus, Escherichia coli and Fusarium thapsinum Open
Background and Objective: Trametes versicolor is important for its medicinal rather than nutritional value. Given the various pharmacological activities of this plant, this study aimed to investigate the antioxidant and antimicrobial poten…
View article: Chemical Constituents, Antioxidant and Cytotoxic Potential of Chloroform and Ethyl Acetate Extracts of Teucrium persicum
Chemical Constituents, Antioxidant and Cytotoxic Potential of Chloroform and Ethyl Acetate Extracts of Teucrium persicum Open
Background: Teucrium persicum, a well-known Iranian endemic plant, has been used to treat various diseases in Iranian traditional medicine. Objectives: This study aimed to assess the antioxidant and cytotoxic effects of chloroform and ethy…
View article: Antioxidant and cytotoxic potentials of the methanolic extract of <i>Teucrium persicum</i> Boiss. in A-375 melanoma cells.
Antioxidant and cytotoxic potentials of the methanolic extract of <i>Teucrium persicum</i> Boiss. in A-375 melanoma cells. Open
T. persicum has significant antioxidant and cytotoxic properties. Surely, more detailed molecular and biochemical studies are needed to find the mechanism(s) behind these effects.
View article: Antibacterial effect of cerium oxide nanoparticle against Pseudomonas aeruginosa
Antibacterial effect of cerium oxide nanoparticle against Pseudomonas aeruginosa Open
View article: Rapid Detection of Aneuploidies in Spontaneous Aborted Fetal Samples by Quantitative Fluorescence-PCR: A Descriptive Study
Rapid Detection of Aneuploidies in Spontaneous Aborted Fetal Samples by Quantitative Fluorescence-PCR: A Descriptive Study Open
Chromosomal aneuploidies are the most chromosomal abnormalities at birth due to maternal meiosis I errors. Pregnancies with autosomal chromosomal aneuploidies that survive are namely trisomies 13 (Patau syndrome), 18 (Edward syndrome), and…
View article: Designing a New Multiepitope-based Vaccine Against COVID-19
Designing a New Multiepitope-based Vaccine Against COVID-19 Open
Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has currently caused a significant pandemic among worldwide populations. The high transmission and mortality rates of the disease necessitate studies for rapid design…
View article: The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties
The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties Open
Medicinal plants and their derived compounds have drawn the attention of researchers due to their considerable impact on human health. Among medicinal plants, mint (Mentha species) exhibits multiple health beneficial properties, such as pr…
View article: Designing a new multi epitope-based vaccine against COVID-19 disease: an immunoinformatic study based on reverse vaccinology approach
Designing a new multi epitope-based vaccine against COVID-19 disease: an immunoinformatic study based on reverse vaccinology approach Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has currently caused a significant pandemic among worldwide populations. The transmission speed and the high rate of mortality caused by the disease necessitate studies for the r…
View article: Association of the -160 C>A Polymorphism in the CDH1 Promoter with Gastric Cancer: A Case-control Study
Association of the -160 C>A Polymorphism in the CDH1 Promoter with Gastric Cancer: A Case-control Study Open
E-cadherin is a tumor suppressor protein that plays a crucial role in cell-cell adherens junction and tissue architecture and it is hypothesized to participate in carcinogenesis. It has been shown that a polymorphism in the upstream of the…
View article: Microsatellite (SSR) amplification by PCR usually led to polymorphic bands: Evidence which shows replication slippage occurs in extend or nascent DNA strands.
Microsatellite (SSR) amplification by PCR usually led to polymorphic bands: Evidence which shows replication slippage occurs in extend or nascent DNA strands. Open
Microsatellites or simple sequence repeats (SSRs) are very effective molecular markers in population genetics, genome mapping, taxonomic study and other large-scale studies. Variation in number of tandem repeats within microsatellite refer…