Sachin Majumdar
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View article: SAT-276 Time Course Of Triglyceride Reduction During IV Insulin Therapy As A Clue To Underlying Genetic Dyslipidemia
SAT-276 Time Course Of Triglyceride Reduction During IV Insulin Therapy As A Clue To Underlying Genetic Dyslipidemia Open
Disclosure: S.I. Suarez: None. S.K. Majumdar: None. Severe hypertriglyceridemia, defined as triglyceride (TG) levels over 1000 mg/dL can result in pancreatitis and is often treated with nothing by mouth status (NPO) and IV insulin. This ty…
View article: MON-761 Familial Hypocalciuric Hypercalcemia Across Three Generations: Exploring Coexistent Primary Hyperparathyroidism
MON-761 Familial Hypocalciuric Hypercalcemia Across Three Generations: Exploring Coexistent Primary Hyperparathyroidism Open
Disclosure: L.I. Guerrero Arroyo: None. A.R. Gonciulea: None. S.K. Majumdar: None. Introduction: Familial Hypocalciuric Hypercalcemia (FHH) is an autosomal dominant condition characterized by hypercalcemia, relative hypocalciuria, and non-…
View article: MON-402 Atypical Parathyroid Tumor Presenting with Normocalcemia and Cytology Features of Follicular Thyroid Neoplasm
MON-402 Atypical Parathyroid Tumor Presenting with Normocalcemia and Cytology Features of Follicular Thyroid Neoplasm Open
Disclosure: S. Ntelis: None. A. Karachaliou: None. S.K. Majumdar: None. Background: Atypical parathyroid tumor (APT) is a rare histological diagnosis with uncertain malignant potential. Clinical presentation typically includes hypercalcemi…
View article: SAT-435 When The Cure Becomes The Cause: Adrenal Insufficiency In Cushing’s Management
SAT-435 When The Cure Becomes The Cause: Adrenal Insufficiency In Cushing’s Management Open
Disclosure: J. Kalluru: None. S. Majumdar: None. Introduction: The therapeutic approach to hormonal disorders like Cushing’s syndrome requires meticulous balance, as interventions aimed at resolving hypercortisolism risk precipitating seco…
View article: SUN-288 Feeling the Heat: A Neuroendocrine Tumor Presenting as “Hot Flashes”
SUN-288 Feeling the Heat: A Neuroendocrine Tumor Presenting as “Hot Flashes” Open
Disclosure: P. Seepaulsingh: None. J. Shah: None. T. Haynes: None. S.K. Majumdar: None. A. Sideri Gugger: None. Background: Although post-menopausal hot flashes persist in a significant percentage of the population even in the late post-me…
View article: MON-778 Optimal Timing of Denosumab with Parathyroidectomy in the Setting of Primary Hyperparathyroidism
MON-778 Optimal Timing of Denosumab with Parathyroidectomy in the Setting of Primary Hyperparathyroidism Open
Disclosure: R.S. MacLeod: None. S.K. Majumdar: None. Introduction: Primary hyperparathyroidism should be considered in patients with elevated PTH once secondary causes like vitamin D deficiency and calcium malabsorption are corrected. Opti…
View article: SUN-629 Hyperproinsulinemia due to a rare variant in the INS gene complicating the diagnosis of post gastric bypass hypoglycemia
SUN-629 Hyperproinsulinemia due to a rare variant in the INS gene complicating the diagnosis of post gastric bypass hypoglycemia Open
Disclosure: S.K. Majumdar: None. M. Shapiro: None. L. Bernacet: None. R. Macleod: None. J. Farrell: None. R. Xicola: None. A 25 y.o. woman with a history of Roux en Y gastric bypass (RYGB) presented with recurrent postprandial hypoglycemia…
View article: 7045 A Rare Case of Lyme-Associated Thyroiditis in an Otherwise Healthy Patient
7045 A Rare Case of Lyme-Associated Thyroiditis in an Otherwise Healthy Patient Open
Disclosure: M. Windham: None. S.K. Majumdar: None. Introduction: Lyme disease, a common tick-borne illness, causes multiorgan inflammation and dysfunction. It commonly affects the musculoskeletal, neurologic, cardiovascular, and integument…
View article: 7029 Changes In Adrenal Gland Size Seen By Linear Assessment On Routine Abdominal CT During Critical Illness
7029 Changes In Adrenal Gland Size Seen By Linear Assessment On Routine Abdominal CT During Critical Illness Open
Disclosure: D.R. Vangipuram: None. N. Bhagat: None. R. Borkar: None. N.T. Mazengia: None. S. Williams, MD: None. S.K. Majumdar: None. Introduction: During acute stress, the hypothalamus-pituitary-adrenal (HPA) axis is activated, ultimately…
View article: 6645 Paraganglioma or Benign Ectopic Thyroid Tissue?
6645 Paraganglioma or Benign Ectopic Thyroid Tissue? Open
Disclosure: J.A. Dower: None. R. MacLeod: None. B. Cardoso: None. C. Matouk: None. S. Mehra: None. G. Riccio: None. L. Williams: None. S.K. Majumdar: None. Introduction: During gestation, cells destined to form the thyroid descend through …
View article: 9365 Now You See Me: The Case Of The Ectopic Thyroid
9365 Now You See Me: The Case Of The Ectopic Thyroid Open
Disclosure: S.I. Suarez: None. S.K. Majumdar: None. Introduction: Lingual thyroid refers to ectopic thyroid tissue located at the base of the tongue or within the thyroglossal tract secondary to failed descent to its usual site (1). Ninety…
View article: An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH)
An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH) Open
View article: OR24-03 Triglyceride Clearance In Hypertriglyceridemic Pancreatitis: Time-course And Implications For Management
OR24-03 Triglyceride Clearance In Hypertriglyceridemic Pancreatitis: Time-course And Implications For Management Open
Disclosure: S.K. Majumdar: None. Introduction: Uncertainty exists for how to optimally manage severely elevated triglyceride (Tg) levels in patients with hypertriglyceridemic (HTg) pancreatitis. Standard recommendations include NPO (nil pe…
View article: FRI694 Hypercalcemia And Renal Failure As Initial Presentation Of A Rare Case Of Primary Splenic Large B Cell Lymphoma
FRI694 Hypercalcemia And Renal Failure As Initial Presentation Of A Rare Case Of Primary Splenic Large B Cell Lymphoma Open
Disclosure: N. Ding: None. S.K. Majumdar: None. Background: Hypercalcemia can be seen in patients with malignancy. However, primary splenic large B cell lymphoma presenting with hypercalcemia and renal failure is rare. Clinical Case: A 75-…
View article: Triglyceride Clearance in Hypertriglyceridemic Pancreatitis: Time Course and Its Implications for Management
Triglyceride Clearance in Hypertriglyceridemic Pancreatitis: Time Course and Its Implications for Management Open
A threshold of 4000 mg/dL for the initial Tg levels in HTg pancreatitis appears to separate patients who are likely to achieve Tg levels of 3 days, independent of cause or treatment. Insulin therapy is appropriate for patients with hypergl…
View article: Diabetic Ketoacidosis Associated with Sodium-Glucose Cotransporter 2 Inhibitors: Clinical and Biochemical Characteristics of 29 Cases
Diabetic Ketoacidosis Associated with Sodium-Glucose Cotransporter 2 Inhibitors: Clinical and Biochemical Characteristics of 29 Cases Open
Context. Numerous reports suggest an association between SGLT2 inhibitors and DKA. Since the use of these drugs for diabetes has increased dramatically, identification of patients at greatest risk of this life-threatening complication is e…
View article: Development and Resolution of Secondary Adrenal Insufficiency after an Intra-Articular Steroid Injection
Development and Resolution of Secondary Adrenal Insufficiency after an Intra-Articular Steroid Injection Open
Corticosteroid injections are commonly indicated in inflammatory conditions involving the soft tissues, tendon sheaths, bursae, and joints. Local corticosteroids carry a lower risk of complications than systemic corticosteroid but may be s…
View article: Spontaneous Adrenal Hemorrhage with Mild Hypoadrenalism in a Patient Anticoagulated with Apixaban for Antiphospholipid Syndrome: A Case Report and Literature Review
Spontaneous Adrenal Hemorrhage with Mild Hypoadrenalism in a Patient Anticoagulated with Apixaban for Antiphospholipid Syndrome: A Case Report and Literature Review Open
Background. Adrenal hemorrhage (AH) is a serious endocrine complication of antiphospholipid syndrome (APLS). Case Presentation. We report a 45-year-old man who presented with several deep venous thromboses and was initially treated with ap…
View article: RF07 | PSUN359 Alpelisib-induced Diabetic Ketoacidosis
RF07 | PSUN359 Alpelisib-induced Diabetic Ketoacidosis Open
Background Alpelisib is an oral α-specific phosphatidylinositol 3-kinase (PI3K) inhibitor use in combination with fulvestrant to treat postmenopausal women with HR+/HER2−, PIK3CA-mutated, advanced or metastatic breast cancer that has acqui…
View article: PMON283 A CASE OF INHALED FLUTICASONE INDUCED ADRENAL INSUFFICIENCY
PMON283 A CASE OF INHALED FLUTICASONE INDUCED ADRENAL INSUFFICIENCY Open
Inhaled glucocorticoids (ICS) are recommended in all patients with persistent asthma. While relatively safe, ICS can occasionally cause systemic side effects including adrenal suppression, bone loss, and cataract formation. We describe a 5…
View article: PSAT364 High-Dose Levothyroxine to Exclude Malabsorption as a Cause of Refractory Hypothyroidism in Hospitalized Patients: Two Cases
PSAT364 High-Dose Levothyroxine to Exclude Malabsorption as a Cause of Refractory Hypothyroidism in Hospitalized Patients: Two Cases Open
Introduction Levothyroxine malabsorption is one of the causes of refractory hypothyroidism. Administration of a single large dose of levothyroxine can help distinguish this from refractory hypothyroidism due to other causes, but little is …
View article: Early-Onset Vascular Dementia in a 43-Year-Old Man with Accelerated Atherosclerotic Disease, Elevated Lipoprotein (a), and a Missense DNAJC5 Variant with Potential Association to Adult-Onset Ceroid Lipofuscinosis
Early-Onset Vascular Dementia in a 43-Year-Old Man with Accelerated Atherosclerotic Disease, Elevated Lipoprotein (a), and a Missense DNAJC5 Variant with Potential Association to Adult-Onset Ceroid Lipofuscinosis Open
Early-onset dementia is defined as dementia occurring prior to the age of 65. Given its impact on physical, mental, and socioeconomic well-being, it is crucial to identify modifiable risk factors. Here, we report a 43-year-old man with ear…
View article: Supplementary Material for: Early-Onset Vascular Dementia in a 43-Year-Old Man with Accelerated Atherosclerotic Disease, Elevated Lipoprotein (a), and a Missense DNAJC5 Variant with Potential Association to Adult-Onset Ceroid Lipofuscinosis
Supplementary Material for: Early-Onset Vascular Dementia in a 43-Year-Old Man with Accelerated Atherosclerotic Disease, Elevated Lipoprotein (a), and a Missense DNAJC5 Variant with Potential Association to Adult-Onset Ceroid Lipofuscinosis Open
Early-onset dementia is defined as dementia occurring prior to the age of 65. Given its impact on physical, mental, and socioeconomic well-being, it is crucial to identify modifiable risk factors. Here, we report a 43-year-old man with ear…
View article: Ventricular fibrillation in Graves disease reveals a rare SCN5A mutation with W1191X variant associated with Brugada syndrome
Ventricular fibrillation in Graves disease reveals a rare SCN5A mutation with W1191X variant associated with Brugada syndrome Open
View article: Fournier’s Gangrene and Diabetic Ketoacidosis Associated with Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Life-Threatening Complications
Fournier’s Gangrene and Diabetic Ketoacidosis Associated with Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Life-Threatening Complications Open
BACKGROUND Sodium glucose co-transporter 2 (SGLT2) inhibitors have become an appealing treatment for diabetes due to their favorable cardiac and renal outcomes. However, reports continue to emerge describing potentially life-threatening ad…
View article: MON-LB035 Adrenal Venous Sampling in the Lateralization of Acth-Independent Cushing Syndrome With Bilateral Adrenal Masses: A Case With a 5-Year Follow-Up
MON-LB035 Adrenal Venous Sampling in the Lateralization of Acth-Independent Cushing Syndrome With Bilateral Adrenal Masses: A Case With a 5-Year Follow-Up Open
Background Nearly 25% of adrenal Cushing syndrome (CS) patients with bilateral adrenal masses have unilateral hypercortisolism, making localization crucial for surgical planning. Since there is no standardized protocol for adrenal venous s…
View article: SAT-515 Anorexia and Severe Hypothyroidism Driving Persistent Ascites and Liver Injury
SAT-515 Anorexia and Severe Hypothyroidism Driving Persistent Ascites and Liver Injury Open
Background Unintentional weight loss, ascites, and altered mental status typically raise concerns for hepatologic-cardiac-oncologic disease. Herein we present a case that after exhaustive workup the etiology of the aforementioned findings …
View article: SUN-700 Fournier’s Gangrene and Diabetic Ketoacidosis Caused by Canagliflozin
SUN-700 Fournier’s Gangrene and Diabetic Ketoacidosis Caused by Canagliflozin Open
Introduction Sodium glucose co-transporter 2 (SGLT2) inhibitors have become an appealing treatment for diabetes due to their favorable cardiac and renal outcomes. However, reports continue to emerge describing potentially life-threatening …
View article: MON-246 A Diagnostic Dilemma of Primary Versus Secondary Thyroid and Adrenal Hormone Insufficiencies: A Unique Case of Widely Metastatic Renal Cell Carcinoma After Brain Radiation
MON-246 A Diagnostic Dilemma of Primary Versus Secondary Thyroid and Adrenal Hormone Insufficiencies: A Unique Case of Widely Metastatic Renal Cell Carcinoma After Brain Radiation Open
Background Identifying the etiology of hormonal insufficiency is important for correct diagnosis and for appropriate hormone supplementation. Usually multiple hormone deficiencies are driven by pituitary pathology, but here we present a ca…