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View article: Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes
Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes Open
View article: Intracellular Mg2+ protects mitochondria from oxidative stress in human keratinocytes
Intracellular Mg2+ protects mitochondria from oxidative stress in human keratinocytes Open
View article: Imaging‐based evaluation of lipids in the stratum corneum by label‐free stimulated Raman scattering microscopy
Imaging‐based evaluation of lipids in the stratum corneum by label‐free stimulated Raman scattering microscopy Open
Dear Editor, The stratum corneum (SC) plays an important role as a barrier against the external environment. Currently, skin barrier function is usually evaluated by measuring trans-epidermal water loss (TEWL), but TEWL measurement does no…
View article: Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes
Magnesium Supplementation Attenuates Ultraviolet-B-Induced Damage Mediated through Elevation of Polyamine Production in Human HaCaT Keratinocytes Open
Magnesium ions (Mg2+) have favorable effects such as the improvement of barrier function and the reduction of inflammation reaction in inflammatory skin diseases. However, its mechanisms have not been fully understood. Microarray analysis …
View article: Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells
Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells Open
Skin barrier damage is present in the patients with hereditary disorders of the magnesium channel, but the molecular mechanism has not been fully understood. We found that the expressions of hyaluronan synthase (HAS), HAS2 and HAS3 are inf…
View article: 地域探究や地域連携をベースにした高等学校 「探究的な学習」入門 : 新潟県阿賀町・新潟大学との連携を事例として
地域探究や地域連携をベースにした高等学校 「探究的な学習」入門 : 新潟県阿賀町・新潟大学との連携を事例として Open
View article: Label-free stimulated Raman scattering microscopy visualizes changes in intracellular morphology during human epidermal keratinocyte differentiation
Label-free stimulated Raman scattering microscopy visualizes changes in intracellular morphology during human epidermal keratinocyte differentiation Open
Epidermal keratinocyte (KC) differentiation, which involves the process from proliferation to cell death for shedding the outermost layer of skin, is crucial for the barrier function of skin. Therefore, in dermatology, it is important to e…
View article: Detection of avian encephalomyelitis virus in chickens in Japan using RT-PCR
Detection of avian encephalomyelitis virus in chickens in Japan using RT-PCR Open
A reverse transcription-polymerase chain reaction (RT-PCR) method was developed for broadly detecting the avian encephalomyelitis virus (AEV). The new primers were based on conserved sequences of the 5'-untranslated region of AEV, because …
View article: Expression level of Orai3 correlates with aging‐related changes in mechanical stimulation‐induced calcium signalling in keratinocytes
Expression level of Orai3 correlates with aging‐related changes in mechanical stimulation‐induced calcium signalling in keratinocytes Open
Epidermis shows morphological and functional alterations with aging: the number of layers of stratum corneum increases, the skin surface becomes dry and flaky, and keratohyalin granules, which produce free amino acids and cornified envelop…