Makoto Gozawa
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View article: Characteristics of Microaneurysm Size in Residual Edema After Intravitreal Injection of Faricimab for Diabetic Macular Edema
Characteristics of Microaneurysm Size in Residual Edema After Intravitreal Injection of Faricimab for Diabetic Macular Edema Open
Background/Objectives: Microaneurysms (MAs) are important in the pathology of diabetic macular edema (DME) and its response to anti-vascular endothelial growth factor (VEGF) therapy. This study aimed to clarify the morphological characteri…
View article: A case of globe rupture crossing calcified senile scleral plaque
A case of globe rupture crossing calcified senile scleral plaque Open
View article: Characterization of the visually impaired patients with diabetes mellitus in Japan
Characterization of the visually impaired patients with diabetes mellitus in Japan Open
Aims/Introduction To conduct a multicenter survey of visually impaired patients with diabetes mellitus (DM) and to identify the physical and ocular characteristics that lead to blindness in Japan. Materials and Methods Visually impaired pa…
View article: Flare levels after intravitreal injection of brolucizumab for diabetic macular edema
Flare levels after intravitreal injection of brolucizumab for diabetic macular edema Open
Purpose This study aimed to evaluate anterior flare intensity (AFI) after intravitreal injection of brolucizumab (IVBr) in patients with diabetic macular edema (DME), and to identify the factors associated with the change of AFI after IVBr…
View article: Turnover of Microaneurysms After Intravitreal Injections of Faricimab for Diabetic Macular Edema
Turnover of Microaneurysms After Intravitreal Injections of Faricimab for Diabetic Macular Edema Open
In the process of improving edema in DME with faricimab, MAs shrink and disappear, and formation of MAs are inhibited, resulting in decreased total number of MAs. Intravitreal administration of faricimab suppresses vascular permeability an…
View article: Relationship between surgical field contamination by patient's exhaled air and the state of the drapes during eye surgery
Relationship between surgical field contamination by patient's exhaled air and the state of the drapes during eye surgery Open
View article: Possibility of surgical field contamination by the patient’s exhaled air: evaluation using a carbon dioxide imaging camera and particle counter
Possibility of surgical field contamination by the patient’s exhaled air: evaluation using a carbon dioxide imaging camera and particle counter Open
The coronavirus disease (COVID-19) pandemic has led to a dramatic increase in facemask use. Consequently, it has been reported that exhaled airflow toward the eyes can cause the dispersal of bacteria into the eyes, potentially increasing t…
View article: Glycemic Control after Initiation of Anti-VEGF Treatment for Diabetic Macular Edema
Glycemic Control after Initiation of Anti-VEGF Treatment for Diabetic Macular Edema Open
Diabetic macular edema (DME) induces visual disturbance, and intravitreal injections of anti-vascular endothelial growth factor (VEGF) drugs are the accepted first-line treatment. We investigate its impact on glycemic control after startin…
View article: Regional Variety of Reduction in Retinal Thickness of Diabetic Macular Edema after Anti-VEGF Treatment
Regional Variety of Reduction in Retinal Thickness of Diabetic Macular Edema after Anti-VEGF Treatment Open
Background and Objectives: The presence of refractory cases resistant to anti-vascular endothelial growth factor (VEGF) therapy for diabetic macular edema (DME) is a problem in clinical practice. This study aimed to explore the less respon…
View article: Publisher Correction: Application of moving particle semi-implicit (MPS) method on retro-oil fluid using three-dimensional vitreous cavity models from magnetic resonance imaging
Publisher Correction: Application of moving particle semi-implicit (MPS) method on retro-oil fluid using three-dimensional vitreous cavity models from magnetic resonance imaging Open
View article: Application of moving particle semi-implicit (MPS) method on retro-oil fluid using three-dimensional vitreous cavity models from magnetic resonance imaging
Application of moving particle semi-implicit (MPS) method on retro-oil fluid using three-dimensional vitreous cavity models from magnetic resonance imaging Open
View article: The Impact of Interval between Recurrence and Reinjection in Anti-VEGF Therapy for Diabetic Macular Edema in Pro Re Nata Regimen
The Impact of Interval between Recurrence and Reinjection in Anti-VEGF Therapy for Diabetic Macular Edema in Pro Re Nata Regimen Open
Background: Pro re nata (PRN) regimen using anti-vascular endothelial growth factor (VEGF) agent is popular for the treatment of diabetic macular edema (DME). We investigated the influence of waiting time (WT) and interval between the date…
View article: Computational fluid dynamics (CFD) simulation analysis on retinal gas cover rates using computational eye models
Computational fluid dynamics (CFD) simulation analysis on retinal gas cover rates using computational eye models Open
View article: Comparison of the intraocular pressure following an intravitreal triamcinolone acetonide injection for diabetic macula oedema in vitrectomised and non-vitrectomised eyes
Comparison of the intraocular pressure following an intravitreal triamcinolone acetonide injection for diabetic macula oedema in vitrectomised and non-vitrectomised eyes Open
Purpose To compare the intraocular pressure (IOP) after an intravitreal triamcinolone acetonide (IVTA) between vitrectomised and non-vitrectomised eyes in patients with diabetes and diabetic macular oedema (DME). Design Retrospective compa…
View article: Microaneurysm density in residual oedema after anti‐vascular endothelial growth factor therapy for diabetic macular oedema
Microaneurysm density in residual oedema after anti‐vascular endothelial growth factor therapy for diabetic macular oedema Open
Purpose To investigate the relationship between microaneurysm (MA) density and residual oedema after intravitreal injection of an anti‐vascular endothelial growth factor agent for the treatment of diabetic macular oedema (DMO). Methods Pat…
View article: Gene expression profile analysis of the rabbit retinal vein occlusion model
Gene expression profile analysis of the rabbit retinal vein occlusion model Open
The rabbit retinal vein occlusion (RVO) model is an experimental system that mimics retinal ischemic diseases in humans. The rabbit RVO model is widely used to assess the therapeutic efficacy of various experimental surgical procedures. In…
View article: Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography
Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography Open
Background To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye drops. Methods Anterior segment optical coherence tomography (AS-OCT) …
View article: Functional and anatomical changes in diabetic macular edema after hemodialysis initiation: One-year follow-up multicenter study
Functional and anatomical changes in diabetic macular edema after hemodialysis initiation: One-year follow-up multicenter study Open
Diabetic nephropathy and retinopathy (DR) including diabetic macular edema (DME) are representative microvascular complications of diabetes. We conducted a retrospective multicenter study analyzing records from patients with DR (132 eyes i…
View article: Evaluation of intraocular gas using magnetic resonance imaging after pars plana vitrectomy with gas tamponade for rhegmatogenous retinal detachment
Evaluation of intraocular gas using magnetic resonance imaging after pars plana vitrectomy with gas tamponade for rhegmatogenous retinal detachment Open
We used magnetic resonance imaging (MRI) to assess how a patient’s posture affects intraocular gas changes and whether the postoperative prone position is required after pars plana vitrectomy (PPV) with gas tamponade for rhegmatogenous ret…
View article: Trabeculectomy followed by phacoemulsification versus trabeculectomy alone: The Collaborative Bleb-Related Infection Incidence and Treatment Study
Trabeculectomy followed by phacoemulsification versus trabeculectomy alone: The Collaborative Bleb-Related Infection Incidence and Treatment Study Open
Phacoemulsification following trabeculectomy adversely affects surgical outcomes. In particular, a shorter time gap between trabeculectomy and phacoemulsification reduces the probability of success.
View article: Prospective Cohort Study on Refractive Changes after Trabeculectomy
Prospective Cohort Study on Refractive Changes after Trabeculectomy Open
We prospectively evaluated refractive changes in the eyes of 97 patients who underwent trabeculectomy at Fukui University Hospital, Fukui, Japan. The primary outcome measure was the refractive change after trabeculectomy. Secondary outcome…
View article: Randomised Clinical Trial for Postoperative Complications after Ex-PRESS Implantation versus Trabeculectomy with 2-Year Follow-Up
Randomised Clinical Trial for Postoperative Complications after Ex-PRESS Implantation versus Trabeculectomy with 2-Year Follow-Up Open
We compared complications between Ex-PRESS implantation and trabeculectomy for 2 years after surgery. Sixty-four open-angle glaucoma eyes were randomly assigned to treatment with trabeculectomy (n = 32) or Ex-PRESS implantation (n = 32). T…
View article: Posterior subtenon infusion of triamcinolone acetonide as adjunctive treatment to panretinal photocoagulation using pattern scan laser for severe diabetic retinopathy
Posterior subtenon infusion of triamcinolone acetonide as adjunctive treatment to panretinal photocoagulation using pattern scan laser for severe diabetic retinopathy Open
View article: Randomized Clinical Trial for Postoperative Complications of Ex-PRESS Implantation versus Trabeculectomy: Complications Postoperatively of Ex-PRESS versus Trabeculectomy Study (CPETS)
Randomized Clinical Trial for Postoperative Complications of Ex-PRESS Implantation versus Trabeculectomy: Complications Postoperatively of Ex-PRESS versus Trabeculectomy Study (CPETS) Open
View article: Direct photocoagulation guided with merged retinal images for the treatment of focal diabetic macular edema.
Direct photocoagulation guided with merged retinal images for the treatment of focal diabetic macular edema. Open
View article: Effect of intravitreal triamcinolone acetonide injection at the end of vitrectomy for vitreous haemorrhage related to proliferative diabetic retinopathy
Effect of intravitreal triamcinolone acetonide injection at the end of vitrectomy for vitreous haemorrhage related to proliferative diabetic retinopathy Open
Background/Aims To investigate whether intravitreal injection of triamcinolone acetonide (IVTA) combined with vitrectomy prevents postoperative inflammation in patients with vitreous haemorrhage (VH) due to proliferative diabetic retinopat…
View article: Direct Photocoagulation Guided by Merged Retinal Images for the Treatment of Focal Diabetic Macular Edema
Direct Photocoagulation Guided by Merged Retinal Images for the Treatment of Focal Diabetic Macular Edema Open
Purpose . To introduce a novel laser photocoagulation (PC) protocol named merged image-guided PC (MIG-PC), which included merging the images of the fundus, optical coherence tomography (OCT) map, and fluorescein angiography (FA). We compar…
View article: Photocoagulation of the Retinal Nonperfusion Area Prevents the Expression of the Vascular Endothelial Growth Factor in an Animal Model
Photocoagulation of the Retinal Nonperfusion Area Prevents the Expression of the Vascular Endothelial Growth Factor in an Animal Model Open
This study is the first using an animal RVO model to demonstrate that laser photocoagulation of the retinal nonperfusion area suppresses VEGF-A expression in the retina.
View article: Comparison of subconjunctival scarring after microincision vitrectomy surgery using 20‐, 23‐, 25‐ and 27‐gauge systems in rabbits
Comparison of subconjunctival scarring after microincision vitrectomy surgery using 20‐, 23‐, 25‐ and 27‐gauge systems in rabbits Open
Purpose To compare subconjunctival scarring after vitrectomy in rabbit eyes using different gauge systems by analysing anterior segment optical coherence tomography ( AS ‐ OCT ) images and histological sections. Methods Vitrectomy using 20…
View article: Panretinal Photocoagulation Using Short-Pulse Laser Induces Less Inflammation and Macular Thickening in Patients with Diabetic Retinopathy
Panretinal Photocoagulation Using Short-Pulse Laser Induces Less Inflammation and Macular Thickening in Patients with Diabetic Retinopathy Open
We compared the effect of panretinal photocoagulation (PRP) using short-pulse laser (SPL) and conventional laser, regardless of the number of spots, in terms of their effect on the progression of diabetic macular edema (DME) and anterior f…