Maksym Jura
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View article: Hemodynamic Factors Driving Peripheral Chemoreceptor Hypersensitivity: Is Severe Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation a Valuable Human Model?
Hemodynamic Factors Driving Peripheral Chemoreceptor Hypersensitivity: Is Severe Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation a Valuable Human Model? Open
Background: A reduction in carotid artery blood flow (CABF) and ultimately in wall shear stress (WSS) is a major driver of heightened peripheral chemoreceptor (PCh) activity in animal models of heart failure. However, it is yet to be trans…
View article: The safety profile of deferred revascularization in patients with coronary artery disease undergoing non-hyperemic functional assessments
The safety profile of deferred revascularization in patients with coronary artery disease undergoing non-hyperemic functional assessments Open
Deferred revascularization guided by dPR and RFR appears safe, with outcomes comparable to FFR-guided decisions in the literature. Larger randomized trials are needed to confirm these findings.
View article: Fractional flow reserve versus solely angiography-guided revascularisation in coronary artery disease. Systematic review and meta-analysis
Fractional flow reserve versus solely angiography-guided revascularisation in coronary artery disease. Systematic review and meta-analysis Open
FFR-driven revascularization was associated with a significantly lower rate of MI for the entire population and also the acute coronary syndrome subset. These results were achieved with substantially fewer revascularization procedures comp…
View article: Effectiveness of remote pulmonary artery pressure estimating in heart failure: systematic review and meta-analysis
Effectiveness of remote pulmonary artery pressure estimating in heart failure: systematic review and meta-analysis Open
View article: Pacemaker Implantation Following Heart Transplantation – Incidence and Risk Factors. Single-Center Experience
Pacemaker Implantation Following Heart Transplantation – Incidence and Risk Factors. Single-Center Experience Open
The need for PM implantation post-HTx despite using new techniques is still common, especially in the group operated with the bicaval method. In addition, higher donor's age and BMI are risk factors of PM implantation, what is of importanc…
View article: Prognostic significance and clinical determinants of residual dyspnoea at discharge in acute heart failure: a single-centre, prospective observational study
Prognostic significance and clinical determinants of residual dyspnoea at discharge in acute heart failure: a single-centre, prospective observational study Open
Objective This study aimed to assess the prognostic significance of residual (discharge) dyspnoea in acute heart failure (AHF) patients. Design Single-centre, prospective observational study. Setting Patients hospitalised for decompensated…
View article: Sex-stratified patterns of emergency cardiovascular admissions prior and during the COVID-19 pandemic
Sex-stratified patterns of emergency cardiovascular admissions prior and during the COVID-19 pandemic Open
View article: Sex-stratified patterns of emergency cardiovascular admissions prior and during the COVID-19 pandemic
Sex-stratified patterns of emergency cardiovascular admissions prior and during the COVID-19 pandemic Open
The COVID-19 pandemic has had a significant impact on global public health, with long-term consequences that are still largely unknown. This study aimed to assess the data regarding acute cardiovascular hospital admissions in five European…
View article: The effects of P2Y12 adenosine receptors’ inhibitors on central and peripheral chemoreflexes
The effects of P2Y12 adenosine receptors’ inhibitors on central and peripheral chemoreflexes Open
Introduction: The most common side effect of ticagrelor is dyspnea, which leads to premature withdrawal of this life-saving medication in 6.5% of patients. Increased chemoreceptors’ sensitivity was suggested as a possible pathophysiologica…
View article: Role of dietary sodium restriction in chronic heart failure: systematic review and meta-analysis
Role of dietary sodium restriction in chronic heart failure: systematic review and meta-analysis Open
Background Dietary sodium restriction remains a guidelines-approved lifestyle recommendation for chronic heart failure (CHF) patients. However, its efficacy in clinical outcome improvement is dubious. Objective The study evaluated whether …
View article: Role of dietary sodium restriction in chronic heart failure. Systematic review and meta-analysis.
Role of dietary sodium restriction in chronic heart failure. Systematic review and meta-analysis. Open
Background Dietary sodium restriction remains guidelines-approved lifestyle recommendation for chronic heart failure (CHF) patients. However, its efficacy in clinical outcome improvement is dubious. Methods We performed a systematic review…
View article: A Methodological Perspective on the Function and Assessment of Peripheral Chemoreceptors in Heart Failure: A Review of Data from Clinical Trials
A Methodological Perspective on the Function and Assessment of Peripheral Chemoreceptors in Heart Failure: A Review of Data from Clinical Trials Open
Augmented peripheral chemoreceptor sensitivity (PChS) is a common feature of many sympathetically mediated diseases, among others, and it is an important mechanism of the pathophysiology of heart failure (HF). It is related not only to the…
View article: Machine Learning Approach to Understand Worsening Renal Function in Acute Heart Failure
Machine Learning Approach to Understand Worsening Renal Function in Acute Heart Failure Open
Acute heart failure (AHF) is a common and severe condition with a poor prognosis. Its course is often complicated by worsening renal function (WRF), exacerbating the outcome. The population of AHF patients experiencing WRF is heterogenous,…
View article: COVID-19 Related Myocarditis in Adults: A Systematic Review of Case Reports
COVID-19 Related Myocarditis in Adults: A Systematic Review of Case Reports Open
Despite the progress of its management, COVID-19 maintains an ominous condition which constitutes a threat, especially for the susceptible population. The cardiac injury occurs in approximately 30% of COVID-19 infections and is associated …
View article: An Artificial Intelligence Approach to Guiding the Management of Heart Failure Patients Using Predictive Models: A Systematic Review
An Artificial Intelligence Approach to Guiding the Management of Heart Failure Patients Using Predictive Models: A Systematic Review Open
Heart failure (HF) is one of the leading causes of mortality and hospitalization worldwide. The accurate prediction of mortality and readmission risk provides crucial information for guiding decision making. Unfortunately, traditional pred…
View article: Novel Phenotyping for Acute Heart Failure—Unsupervised Machine Learning-Based Approach
Novel Phenotyping for Acute Heart Failure—Unsupervised Machine Learning-Based Approach Open
Acute heart failure (AHF) is a life-threatening, heterogeneous disease requiring urgent diagnosis and treatment. The clinical severity and medical procedures differ according to a complex interplay between the deterioration cause, underlyi…
View article: Fractional flow reserve-guided treatment in coronary artery disease: Clinical practice
Fractional flow reserve-guided treatment in coronary artery disease: Clinical practice Open
The assessment of functional severity of moderate coronary stenoses is challenging. Coronary angiography remains the standard technique for diagnosis, although, due to its limitations, it is frequently insufficient to detect relevant myoca…
View article: X-linked adrenoleukodystrophy diagnosed in three brothers
X-linked adrenoleukodystrophy diagnosed in three brothers Open
Adrenoleukodystrophy is a genetic diseases classified in the group of peroxisomal disorders caused by mutations in ABCD1, gene located on the X chromosome (Xq28). It demonstrates X-linked recessive inheritance. There is an accumulation of …