Maliha Ghaffar
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View article: Nanoparticles in Infectious Disease Control: Microbial Synthesis, Antimicrobial Mechanisms, and Therapeutic Innovations
Nanoparticles in Infectious Disease Control: Microbial Synthesis, Antimicrobial Mechanisms, and Therapeutic Innovations Open
The escalating threat of multidrug-resistant (MDR) pathogens has underscored the urgent need for innovative strategies to combat infectious diseases. Nanoparticles (NPs) have emerged as a versatile platform due to their unique physicochemi…
View article: THERAPEUTIC CRISPR/CAS9 GENOME EDITING TOOL FOR TREATING SICKLE CELL DISEASE
THERAPEUTIC CRISPR/CAS9 GENOME EDITING TOOL FOR TREATING SICKLE CELL DISEASE Open
Sickle cell disease (SCD) is a serious inherited condition that leads to high rates of illness and mortality, and a complete cure is not yet available. Recent advances suggest that correcting the genetic mutations in hematopoietic stem/pro…
View article: MAGEA6 positively regulates MSMO1 and promotes the migration and invasion of oesophageal cancer cells
MAGEA6 positively regulates MSMO1 and promotes the migration and invasion of oesophageal cancer cells Open
The melanoma antigen gene family A (MAGEA) family of proteins comprises of cancer-testis antigens that are highly expressed in a number of tumours but are minimally expressed in normal cells. Due to its expression characteristics, this pro…
View article: Investigation into the expression levels of MAGEA6 in esophageal squamous cell carcinoma and esophageal adenocarcinoma tissues
Investigation into the expression levels of MAGEA6 in esophageal squamous cell carcinoma and esophageal adenocarcinoma tissues Open
Esophageal carcinoma (EC) is the sixth most deadly of all cancers. It is among the most malignant cancers due to its highly aggressive nature and low survival rate. The incidence of EC is high in Asia, particularly in Southern areas includ…
View article: Down-Regulation of Long Non-Coding RNA CASC9 Suppresses the Migration and Invasion of Esophageal Cancer Cells
Down-Regulation of Long Non-Coding RNA CASC9 Suppresses the Migration and Invasion of Esophageal Cancer Cells Open
The objective of the study was to investigate the role of CASC9 in esophageal cancer cells migration and invasion. Expression of long noncoding RNA (lncRNA) CASC9 was found high in esophageal cancer cells by qRT-PCR. The CASC9 knockdown ef…
View article: Long Non-coding RNA LINC01234 Regulates Proliferation, Invasion and Apoptosis in Esophageal Cancer Cells
Long Non-coding RNA LINC01234 Regulates Proliferation, Invasion and Apoptosis in Esophageal Cancer Cells Open
Esophageal cancer is one of the leading malignancies globally and long non-coding RNAs (lncRNAs) have been proved to have an important role in different malignancies including esophageal cancer. However their role in disease progression is…
View article: Expressions of the Cell Cycle Relative Proteins in Esophageal Cancer Tissues
Expressions of the Cell Cycle Relative Proteins in Esophageal Cancer Tissues Open
The aim of the research is to investigate the expression of the cell cycle relative proteins (P53, P16, Cyclin D1, and Ki67) in Esophageal Cancer (EC) patients of the Chaoshan area, China. In China, Chaoshan has the high incidence of EC. D…
View article: Water Carcinogenicity and Prevalence of HPV Infection in Esophageal Cancer Patients in Huaihe River Basin, China
Water Carcinogenicity and Prevalence of HPV Infection in Esophageal Cancer Patients in Huaihe River Basin, China Open
Objective . The incidence of the upper gastrointestinal tumor has increased rapidly during recent decades. The relationship between local water pollution and the tumor is still not much clear, so this study was conducted to further investi…
View article: Expression of CASC9 and LINC01234 in Different Cell Lines
Expression of CASC9 and LINC01234 in Different Cell Lines Open
Cancers are multifactorial but the advancement in research in the recent decades have drawn attention towards lncRNAs as they are proven to play important function as biological regulators. LINC01234, CASC9 are important long non coding RN…