Malin Sund
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View article: Stromal collagen IV expression and risk of breast cancer death in ductal carcinoma in situ
Stromal collagen IV expression and risk of breast cancer death in ductal carcinoma in situ Open
Background Current treatment for ductal carcinoma in situ (DCIS) of the breast is generic, due to lack of risk stratification tools. We investigate the correlation between expression of collagen IV in the breast and risk of dying of breast…
View article: Postoperative complications and their risk factors in breast cancer patients treated with neoadjuvant chemotherapy
Postoperative complications and their risk factors in breast cancer patients treated with neoadjuvant chemotherapy Open
Postoperative complications were common yet in most cases treated in an outpatient setting. Patients with higher age and BMI, and those operated with mastectomy and/or ALND were in greater risk of developing postoperative complications. Th…
View article: The prognostic significance of MMP-8 tissue Immunoexpression in pancreatic ductal adenocarcinoma after neoadjuvant therapy
The prognostic significance of MMP-8 tissue Immunoexpression in pancreatic ductal adenocarcinoma after neoadjuvant therapy Open
Neoadjuvant therapy (NAT) has become increasingly common in pancreatic ductal adenocarcinoma (PDAC). Still, PDAC remains one of the deadliest cancers and clinically useful biomarkers are needed. Matrix metalloproteinase 8 (MMP-8) has previ…
View article: Sex Disparities and Female Reproductive and Hormonal Factors Associated with Risk of Pancreatic Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort
Sex Disparities and Female Reproductive and Hormonal Factors Associated with Risk of Pancreatic Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort Open
Background/Objectives: Worldwide, men experience a higher incidence of pancreatic cancer (PC) than women. Methods: To increase understanding of the underlying reasons for this sex-related difference, we analysed general and sex-related ris…
View article: Stromal collagen IV expression and risk of breast cancer death in ductal carcinoma in situ
Stromal collagen IV expression and risk of breast cancer death in ductal carcinoma in situ Open
Background. Current treatment for ductal carcinoma in situ (DCIS) of the breast is generic, due to lack of risk stratification tools. We investigate the correlation between expression of collagen IV in the breast and risk of breast cancer …
View article: The expanding role of surgery in metastatic disease: A modern perspective
The expanding role of surgery in metastatic disease: A modern perspective Open
Special issue: Metastasis surgery
View article: Exposure to androgen deprivation therapy and risk of anastomotic leakage after colorectal cancer surgery
Exposure to androgen deprivation therapy and risk of anastomotic leakage after colorectal cancer surgery Open
Aim The risk of anastomotic leakage after colorectal cancer surgery is higher in men, regardless of the anatomical location. Previous studies suggest that this might be due to hormonal differences. The aim of this work was to investigate w…
View article: <i>BJS</i> commission on the surgical management of the axilla in breast cancer
<i>BJS</i> commission on the surgical management of the axilla in breast cancer Open
Introduction: The management of breast cancer has evolved dramatically over the past 25 years. In stark contrast to the radical mastectomy proposed by Halsted1 over 100 years ago, patients can benefit from individualized treatment programm…
View article: Self-reported witnessed episodes of apnea during sleep is associated with incident lung and breast cancer
Self-reported witnessed episodes of apnea during sleep is associated with incident lung and breast cancer Open
Self-reported witnessed sleep apnea is associated with an increased risk of developing lung- and breast cancer. There is a multiplicative effect of reporting witnessed sleep apnea and ever-smoking with an over 5 times increase on the hazar…
View article: Cohort Profile: The Northern Sweden Health and Disease Study (NSHDS)
Cohort Profile: The Northern Sweden Health and Disease Study (NSHDS) Open
Key features: The Northern Sweden Health and Disease Study (NSHDS) was initiated in the mid-1980s. The NSHDS is a population-based prospective longitudinal cohort comprising >140 000 participants in the two northernmost regions in Sweden, …
View article: Intratumoural expression of dihydropyrimidine dehydrogenase is an independent prognostic factor in resected pancreatic ductal adenocarcinoma treated with adjuvant gemcitabine
Intratumoural expression of dihydropyrimidine dehydrogenase is an independent prognostic factor in resected pancreatic ductal adenocarcinoma treated with adjuvant gemcitabine Open
Pancreatic ductal adenocarcinoma (PDAC) is associated with a poor prognosis, and biomarkers to guide treatment decisions in PDAC are generally lacking. Intratumoural expression of dihydropyrimidine dehydrogenase (DPD) is a potential progno…
View article: High prevalence of pancreatic steatosis in pancreatic cancer patients: A meta-analysis and systematic review
High prevalence of pancreatic steatosis in pancreatic cancer patients: A meta-analysis and systematic review Open
PDAC patients have a high prevalence of PS, and they are significantly more likely to have PS compared to controls. These findings emphasize the need to prioritize a standardized approach to the diagnosis, follow-up, and treatment of PS, w…
View article: Axillary clearance and chemotherapy rates in ER+HER2− breast cancer: secondary analysis of the SENOMAC trial
Axillary clearance and chemotherapy rates in ER+HER2− breast cancer: secondary analysis of the SENOMAC trial Open
Swedish Research Council, Swedish Cancer Society, Nordic Cancer Union, Swedish Breast Cancer Association.
View article: Prediction of High Nodal Burden in Patients With Sentinel Node–Positive Luminal <i>ERBB2</i>-Negative Breast Cancer
Prediction of High Nodal Burden in Patients With Sentinel Node–Positive Luminal <i>ERBB2</i>-Negative Breast Cancer Open
Importance In patients with clinically node-negative (cN0) breast cancer and 1 or 2 sentinel lymph node (SLN) macrometastases, omitting completion axillary lymph node dissection (CALND) is standard. High nodal burden (≥4 axillary nodal met…
View article: Supplementary Table S7 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S7 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S7 shows results of univariate analysis for 36 biopsy-confirmed nonalcoholic fatty liver disease SNPs in the PanC4 sample
View article: Supplementary Table S8 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S8 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S8 shows results of univariate analysis for 17 imaging and biopsy validated SNPs in the PanC4 sample
View article: Supplementary Table S3 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S3 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S3 shows results of univariate analysis for 36 biopsy-confirmed nonalcoholic fatty liver disease SNPs in the PanScan sample
View article: Supplementary Table S3 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S3 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S3 shows results of univariate analysis for 36 biopsy-confirmed nonalcoholic fatty liver disease SNPs in the PanScan sample
View article: Supplementary Table S5 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S5 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S5 shows results of univariate analysis for 77 chronically elevated serum alanine aminotransferase (cALT)-defined nonalcoholic fatty liver disease in the Pancreatic Cancer Case-Control Consortium (PanC4) data
View article: Supplementary Table S1 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S1 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S1 shows results of univariate analysis for 77 chronically elevated serum alanine aminotransferase (cALT)-defined nonalcoholic fatty liver disease SNPs in the Pancreatic Cancer Cohort Consortium (PanScan) data
View article: Supplementary Table S9 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S9 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S9 shows descriptive Statistics for PanScan sample
View article: Supplementary Table S5 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S5 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S5 shows results of univariate analysis for 77 chronically elevated serum alanine aminotransferase (cALT)-defined nonalcoholic fatty liver disease in the Pancreatic Cancer Case-Control Consortium (PanC4) data
View article: Supplementary Table S10 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S10 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S10 shows descriptive Statistics for PanC4 sample
View article: Supplementary Figure S2 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Figure S2 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Figure S2 shows forest plot for minimally adjusted model for PanC4 sample
View article: Supplementary Table S2 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S2 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S2 shows results of univariate analysis for 22 imaging-defined nonalcoholic fatty liver disease SNPs in the PanScan sample
View article: Supplementary Figure S1 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Figure S1 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Figure S1 shows forest plot for minimally adjusted model for the PanScan sample.
View article: Supplementary Table S4 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S4 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S4 shows results of univariate analysis for 17 imaging and biopsy validated SNPs in the PanScan sample
View article: Supplementary Table S10 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Supplementary Table S10 from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Supplementary Table S10 shows descriptive Statistics for PanC4 sample
View article: Data from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization
Data from Genetic susceptibility to nonalcoholic fatty liver disease and risk for pancreatic cancer: Mendelian randomization Open
Background: There are conflicting data on whether nonalcoholic fatty liver disease (NAFLD) is associated with susceptibility to pancreatic cancer (PC). Using Mendelian randomization (MR), we investigated the relationship between genetic pr…