Mamta K. Jain
YOU?
Author Swipe
View article: Charity coverage and decreased COVID-19 mortality among uninsured patients in Texas: A retrospective cohort study
Charity coverage and decreased COVID-19 mortality among uninsured patients in Texas: A retrospective cohort study Open
Purpose Decreased access to care and social drivers of health have been implicated in COVID-19 disparities. The objective of this study was to test the association between county-funded charity coverage (CFCC) and mortality among uninsured…
View article: Charity coverage and decreased COVID-19 mortality among uninsured patients in Texas: A retrospective cohort study
Charity coverage and decreased COVID-19 mortality among uninsured patients in Texas: A retrospective cohort study Open
Purpose Decreased access to care and social drivers of health have been implicated in COVID-19 disparities. The objective of this study was to test the association between county-funded charity coverage (CFCC) and mortality among uninsured…
View article: HIV Incidence Could Rise by 68% in 11 States if Ryan White Ends: A Simulation Study
HIV Incidence Could Rise by 68% in 11 States if Ryan White Ends: A Simulation Study Open
Objectives To estimate the increase in HIV infections in 11 US states if Ryan White services are interrupted or ended. Methods We applied a population-level model of HIV transmission to 11 states. We represented the proportion of people wi…
View article: SARS-Cov-2 vaccination strategies in hospitalized recovered COVID-19 patients: a randomized clinical trial (VATICO Trial)
SARS-Cov-2 vaccination strategies in hospitalized recovered COVID-19 patients: a randomized clinical trial (VATICO Trial) Open
View article: Long-term outcomes of passive immunotherapy for COVID-19: a pooled analysis of a large multinational platform randomized clinical trial
Long-term outcomes of passive immunotherapy for COVID-19: a pooled analysis of a large multinational platform randomized clinical trial Open
View article: Peripartum Cardiomyopathy: A Case Series about the Conundrum of Anaesthetic Management
Peripartum Cardiomyopathy: A Case Series about the Conundrum of Anaesthetic Management Open
Peripartum Cardiomyopathy (PPCM) is a rare, potentially life-threatening condition characterised by left ventricular dysfunction and heart failure, occurring in the last month of pregnancy or within five months of delivery. Anaesthetic man…
View article: P-979. Clinician Willingness to Consider Long-Acting Therapies and Culturally Supportive Strategies in Caring for Heavily Treatment-Experienced Black, Indigenous, or People of Color (BIPOC) with HIV
P-979. Clinician Willingness to Consider Long-Acting Therapies and Culturally Supportive Strategies in Caring for Heavily Treatment-Experienced Black, Indigenous, or People of Color (BIPOC) with HIV Open
Background Black, Indigenous, or People of Color (BIPOC) are overrepresented among heavily treatment-experienced (HTE) people with HIV (PWH). They face complex treatment challenges, exacerbated by socioeconomic disadvantages, and cultural …
View article: Sociodemographic Disparities in Hepatitis B Treatment: A Real-World Analysis of 3 Safety-Net Health Systems in the United States
Sociodemographic Disparities in Hepatitis B Treatment: A Real-World Analysis of 3 Safety-Net Health Systems in the United States Open
Background Timely treatment of chronic hepatitis B (CHB) reduces risks of cirrhosis and hepatocellular carcinoma. Gaps in timely treatment persist, especially among underserved safety-net populations. We aim to evaluate gaps and disparitie…
View article: STOP-HCV-HCC Program: Privacy-Preserving Innovation for Remote Data Access Analytics at Federally Qualified Health Centers in South Texas
STOP-HCV-HCC Program: Privacy-Preserving Innovation for Remote Data Access Analytics at Federally Qualified Health Centers in South Texas Open
STOP-HCV-HCC program to screen and treat hepatitis C, vaccinate for hepatitis B, and prevent hepatocellular carcinoma is implementing a cloud-based privacy-preserving platform to overcome electronic health record barriers to reporting, wit…
View article: Viral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19
Viral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19 Open
Background Persistent mortality in adults hospitalized due to acute COVID-19 justifies pursuit of disease mechanisms and potential therapies. The aim was to evaluate which virus and host response factors were associated with mortality risk…
View article: Lessons learned from the conduct of inpatient clinical trials in a pandemic
Lessons learned from the conduct of inpatient clinical trials in a pandemic Open
Background: The COVID-19 pandemic amplified known challenges associated with the conduct of inpatient clinical trials, while also introducing new ones that needed to be addressed. Methods: Stakeholders based in the United States who partic…
View article: Weight Gain in a Large HIV Clinic in the Southern United States: Comparative Analysis of Initial Antiretroviral Therapy
Weight Gain in a Large HIV Clinic in the Southern United States: Comparative Analysis of Initial Antiretroviral Therapy Open
View article: Persistent CMV pneumonitis in HIV infection: a case report
Persistent CMV pneumonitis in HIV infection: a case report Open
We present a rare case of pathology-proven CMV pneumonitis in a patient with HIV infection after presenting with cough and fever. This presentation was complicated by recurrence of symptoms after treatment in the setting of continued uncon…
View article: 2502. Best Practice Alert for Hepatitis C Virus Screening Demonstrates Importance of Reminders during Disruptive Times (COVID-19)
2502. Best Practice Alert for Hepatitis C Virus Screening Demonstrates Importance of Reminders during Disruptive Times (COVID-19) Open
Background In 2015, a Best Practice Alert (BPA) was implemented into our electronic health record that prompts ordering of Hepatitis C Virus (HCV) antibody (Ab) screens for unscreened patients born between 1945-1965 (baby boomers: BB). The…
View article: 2495. Inpatient Hepatitis C Virus Testing Increased During the COVID-19 Pandemic
2495. Inpatient Hepatitis C Virus Testing Increased During the COVID-19 Pandemic Open
Background We have observed an unexpected increase in hepatitis C virus (HCV) testing in the inpatient setting since the beginning of the COVID-19 pandemic. We hypothesized that this increase was driven by abnormal liver function tests (LF…
View article: Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19
Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19 Open
Background Neutralizing monoclonal antibodies (nmAbs) failed to show clear benefit for hospitalized patients with coronavirus disease 2019 (COVID-19). Dynamics of virologic and immunologic biomarkers remain poorly understood. Methods Parti…
View article: Who Is at Risk for New Hepatitis B Infections Among People With HIV?
Who Is at Risk for New Hepatitis B Infections Among People With HIV? Open
Hepatitis B virus (HBV) increases morbidity and mortality among people with HIV (PWH). We retrospectively analyzed HBV incidence among 5785 PWH. Fourteen had newly positive hepatitis B s antigen (mean 5.2 person-years of follow-up, 46.4/10…
View article: Persistent low prevalence of hepatitis B vaccination among people with <scp>HIV</scp>: Time for a change?
Persistent low prevalence of hepatitis B vaccination among people with <span>HIV</span>: Time for a change? Open
Hepatitis B virus (HBV) infection is one of the leading causes of hepatocellular carcinoma and mortality among people living with HIV (PLWH). HBV vaccination provides protection from infection; however, vaccination rates are low. We conduc…
View article: Derivation of a Protein Risk Score for Cardiovascular Disease Among a Multiracial and Multiethnic HIV+ Cohort
Derivation of a Protein Risk Score for Cardiovascular Disease Among a Multiracial and Multiethnic HIV+ Cohort Open
Background Cardiovascular disease risk prediction models underestimate CVD risk in people living with HIV (PLWH). Our goal is to derive a risk score based on protein biomarkers that could be used to predict CVD in PLWH. Methods and Results…
View article: Understanding the treatment benefit of hyperimmune anti-influenza intravenous immunoglobulin (Flu-IVIG) for severe human influenza
Understanding the treatment benefit of hyperimmune anti-influenza intravenous immunoglobulin (Flu-IVIG) for severe human influenza Open
BACKGROUNDAntibody-based therapies for respiratory viruses are of increasing importance. The INSIGHT 006 trial administered anti-influenza hyperimmune intravenous immunoglobulin (Flu-IVIG) to patients hospitalized with influenza. Flu-IVIG …
View article: Human immunodeficiency virus coinfection differentially impacts hepatitis B virus viral markers based on hepatitis Be antigen status in patients with suppressed viremia
Human immunodeficiency virus coinfection differentially impacts hepatitis B virus viral markers based on hepatitis Be antigen status in patients with suppressed viremia Open
Hepatitis B virus (HBV) RNA and hepatitis B core‐related antigen (HBcrAg), reflecting transcriptional activity of covalently closed circular DNA, are gaining traction as important markers to assess viral activity. Whether their expression …
View article: Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case
Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case Open
Background Clinical trials initiated during emerging infectious disease outbreaks must quickly enroll participants to identify treatments to reduce morbidity and mortality. This may be at odds with enrolling a representative study populati…
View article: Anaesthetic Management of a Child with Parapharyngeal Abscess
Anaesthetic Management of a Child with Parapharyngeal Abscess Open
View article: 1397. COVID-19 Hospitalizations in North Texas: Impact of Insurance Status
1397. COVID-19 Hospitalizations in North Texas: Impact of Insurance Status Open
Background Texas has one of the highest rates of uninsured populations in the US (Fig1). We hypothesized that those without insurance were more likely to be hospitalized for COVID-19 but were at higher risk for severe disease and mortality…
View article: 1396. COVID-19 Hospitalization Impact of Age, Race and Ethnicity Among Medicaid and Uninsured
1396. COVID-19 Hospitalization Impact of Age, Race and Ethnicity Among Medicaid and Uninsured Open
Background Texas has one of the highest rates of uninsured patients in the US and is one of the few states that has not expanded Medicaid (Fig 1). We sought to examine if there were differences by age, race, and ethnicity in the risk COVID…
View article: Temporal Improvements in COVID-19 Outcomes for Hospitalized Adults: A Post Hoc Observational Study of Remdesivir Group Participants in the Adaptive COVID-19 Treatment Trial
Temporal Improvements in COVID-19 Outcomes for Hospitalized Adults: A Post Hoc Observational Study of Remdesivir Group Participants in the Adaptive COVID-19 Treatment Trial Open
National Institute of Allergy and Infectious Diseases.
View article: Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity
Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity Open
Immune cell state alterations rewire HIV-1 gene expression, thereby influencing viral latency and reactivation, but the mechanisms are still unfolding. Here, using a screen approach on CD4+ T cell models of HIV-1 latency, we revealed Small…
View article: Atovaquone for treatment of COVID-19: A prospective randomized, double-blind, placebo-controlled clinical trial
Atovaquone for treatment of COVID-19: A prospective randomized, double-blind, placebo-controlled clinical trial Open
Background: An in silico screen was performed to identify FDA approved drugs that inhibit SARS-CoV-2 main protease (M pro ), followed by in vitro viral replication assays, and in vivo pharmacokinetic studies in mice. These studies identifi…
View article: The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19
The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19 Open
U.S. government Operation Warp Speed and National Institute of Allergy and Infectious Diseases.
View article: Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19
Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 Open
National Institutes of Health.