Man Bock Gu
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View article: Depletion of proteasome subunit PSMD1 induces cancer cell death via protein ubiquitination and DNA damage, irrespective of p53 status
Depletion of proteasome subunit PSMD1 induces cancer cell death via protein ubiquitination and DNA damage, irrespective of p53 status Open
Hepatocellular carcinoma (HCC) is characterized by high incidence and fatality rates worldwide. In our exploration of prognostic factors in HCC, the 26s proteasome subunit, non-ATPase 1 (PSMD1) protein emerged as a significant contributor,…
View article: Proteomic analysis of plasma to identify novel biomarkers for intra-amniotic infection and/or inflammation in preterm premature rupture of membranes
Proteomic analysis of plasma to identify novel biomarkers for intra-amniotic infection and/or inflammation in preterm premature rupture of membranes Open
To identify potential plasma biomarkers associated with microbial invasion of the amniotic cavity (MIAC) and/or intraamniotic inflammation (IAI) in women with preterm premature rupture of membranes (PPROM). This retrospective cohort study …
View article: Proteomic analysis of plasma to identify novel biomarkers for intra-amniotic infection and/or inflammation in preterm premature rupture of membranes
Proteomic analysis of plasma to identify novel biomarkers for intra-amniotic infection and/or inflammation in preterm premature rupture of membranes Open
This study aimed to identify potential plasma biomarkers associated with microbial invasion of the amniotic cavity (MIAC) and/or intraamniotic inflammation (IAI) in women with preterm premature rupture of membranes (PPROM). This retrospect…
View article: Extracellular vesicle-guided in situ reprogramming of synovial macrophages for the treatment of rheumatoid arthritis
Extracellular vesicle-guided in situ reprogramming of synovial macrophages for the treatment of rheumatoid arthritis Open
Activation state of synovial macrophages is significantly correlated with disease activity and severity of rheumatoid arthritis (RA) and provides valuable clues for RA treatment. Classically activated M1 macrophages in inflamed synovial jo…
View article: Salivary microbiota in periodontal health and disease and their changes following nonsurgical periodontal treatment
Salivary microbiota in periodontal health and disease and their changes following nonsurgical periodontal treatment Open
Our results revealed differences in the taxa of salivary microbiota between conditions of periodontal health and disease. The taxa found to be associated with health or disease have potential for use as salivary biomarkers for periodontal …
View article: Angle-multiplexed all-dielectric metasurfaces for broadband molecular fingerprint retrieval
Angle-multiplexed all-dielectric metasurfaces for broadband molecular fingerprint retrieval Open
Angle-multiplexed dielectric metasurfaces enable sensitive molecular fingerprint detection without the need for spectrometry.
View article: The sensitive detection of ODAM by using sandwich-type biosensors with a cognate pair of aptamers for the early diagnosis of periodontal disease
The sensitive detection of ODAM by using sandwich-type biosensors with a cognate pair of aptamers for the early diagnosis of periodontal disease Open
This research aims to develop biosensors which could diagnose periodontal diseases in early phases and predict the illness stage of patients, in order to give them adequate treatment timely. Human odontogenic ameloblast-associated protein …
View article: Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells
Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells Open
Protein arginine methyltransferase 5 (PRMT5) is a protein that catalyzes transfer of methyl groups to the arginine residues of proteins and is involved in diverse cellular and biological responses. While the participation of PRMT5 in cance…
View article: Additional file 2: of Bio-hybrid inorganic microparticles derived from CO2 for highly efficient and selective removal of antibiotics
Additional file 2: of Bio-hybrid inorganic microparticles derived from CO2 for highly efficient and selective removal of antibiotics Open
Table S1. Physical properties of mag-SiCC. (XLSX 10 kb)
View article: Highly amplified detection of visceral adipose tissue-derived serpin (vaspin) using a cognate aptamer duo
Highly amplified detection of visceral adipose tissue-derived serpin (vaspin) using a cognate aptamer duo Open
A cognate aptamer duo for visceral adipose tissue-derived serpin (vaspin) which distinctively bind to two different sites on vaspin with high affinity and specificity were successfully developed by using graphene oxide-based systematic evo…
View article: High-throughput prescreening of pharmaceuticals using a genome-wide bacterial bioreporter array
High-throughput prescreening of pharmaceuticals using a genome-wide bacterial bioreporter array Open
We assessed the applicability of multi-strain bacterial bioreporter bioassays to drug screening. To this end, we investigated the reactions of a panel of 15 luminescent recombinant Escherichia coli bacterial bioreporters to a library of 42…
View article: A novel reflectance-based aptasensor using gold nanoparticles for the detection of oxytetracycline
A novel reflectance-based aptasensor using gold nanoparticles for the detection of oxytetracycline Open
We present a novel reflectance-based colorimetric aptasensor using gold nanoparticles for the detection of oxytetracycline for the first time.