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View article: Establishing biomarkers and clinical endpoints in myotonic dystrophy type 1 (END-DM1): Protocol of an international natural history study
Establishing biomarkers and clinical endpoints in myotonic dystrophy type 1 (END-DM1): Protocol of an international natural history study Open
Background Myotonic dystrophy type 1 (DM1) is an autosomal dominant inherited multi-system disorder that affects skeletal muscles but also many other organ systems. Molecular targets have been identified and targeted therapies are being de…
View article: Vitamin D normative values by age, sex, and supplement use
Vitamin D normative values by age, sex, and supplement use Open
View article: Assessing Pediatric Endodontic Referrals to University-Based Clinics: A Retrospective Chart Review
Assessing Pediatric Endodontic Referrals to University-Based Clinics: A Retrospective Chart Review Open
Background: Timely dental care is essential to prevent complications and preserve natural teeth, yet inefficient referral practices, low reimbursement rates and systemic barriers continue to disproportionately affect Medicaid-enrolled chil…
View article: HPV Prevention in Men: A Narrative Review of Strategies, Risks, and Public Health Implications
HPV Prevention in Men: A Narrative Review of Strategies, Risks, and Public Health Implications Open
Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide, impacting both males and females. In men, HPV causes genital warts, more than 90% of anal cancers, and 60% of oropharyngeal cancers. Given that one in …
View article: Integrating Dentistry into Interprofessional Healthcare: A Scoping Review on Advancing Collaborative Practice and Patient Outcomes
Integrating Dentistry into Interprofessional Healthcare: A Scoping Review on Advancing Collaborative Practice and Patient Outcomes Open
Background: Interprofessional collaboration is vital for comprehensive, patient-centered care. Despite growing recognition of oral–systemic health links, the integration of dentists into healthcare teams remains limited. This scoping revie…
View article: Focus group interviews as a clinical research immersion experience
Focus group interviews as a clinical research immersion experience Open
Background Research is an essential component of the dental profession and should be integrated into dental education and training curricula. Opportunities to participate in clinical research studies can enrich the learning experience of t…
View article: Influence of Ultrasonic Activation of Endodontic Irrigants on Microbial Reduction and Postoperative Pain: A Scoping Review of In Vivo Studies
Influence of Ultrasonic Activation of Endodontic Irrigants on Microbial Reduction and Postoperative Pain: A Scoping Review of In Vivo Studies Open
Objective: Root canal irrigation plays a critical role in achieving effective chemomechanical disinfection during endodontic therapy. Conventional syringe irrigation, typically using sodium hypochlorite, ethylenediaminetetraacetic acid, an…
View article: Treating Temporomandibular Disorders Through Orthodontics: A Scoping Review of Evidence, Gaps, and Clinical Guidance
Treating Temporomandibular Disorders Through Orthodontics: A Scoping Review of Evidence, Gaps, and Clinical Guidance Open
Introduction: Evidence on orthodontic interventions for temporomandibular disorders (TMD) is fragmented and inconclusive, creating a gap in guidance for clinical decision-making. This study addresses that gap by evaluating current knowledg…
View article: Timing of Treatment for Patients with Hypertrophic Maxillary Labial Frena
Timing of Treatment for Patients with Hypertrophic Maxillary Labial Frena Open
Background/Objectives: The maxillary labial frenum (MLF) is a connective tissue structure attaching the upper lip to the maxillary alveolar process. Its morphology varies significantly among individuals and is often most prominent during e…
View article: Where You Place, How You Load: A Scoping Review of the Determinants of Orthodontic Mini-Implant Success
Where You Place, How You Load: A Scoping Review of the Determinants of Orthodontic Mini-Implant Success Open
Objective: This scoping review identifies and analyzes factors influencing the effectiveness of orthodontic mini-implants and temporary anchorage devices in orthodontic treatments, including clinical applications, success rates, and associ…
View article: Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1): protocol of an international natural history study
Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1): protocol of an international natural history study Open
Background Myotonic dystrophy type 1 (DM1) is an autosomal dominant inherited multi-system disorder that affects skeletal muscles but also many other organ systems. Molecular targets have been identified and targeted therapies are being de…
View article: Charting New Territory: AI Applications in Dental Caries Detection from Panoramic Imaging
Charting New Territory: AI Applications in Dental Caries Detection from Panoramic Imaging Open
Introduction: Dental caries remains a public health concern, and early detection prevents its progression and complications. Panoramic radiographs are essential diagnostic tools, yet the interpretation of panoramic X-rays varies among prac…
View article: Pacifier Use and Its Influence on Pediatric Malocclusion: A Scoping Review of Emerging Evidence and Developmental Impacts
Pacifier Use and Its Influence on Pediatric Malocclusion: A Scoping Review of Emerging Evidence and Developmental Impacts Open
Background/Objectives: Pacifier use is a widespread soothing practice during infancy, but extended use has been linked to adverse dental outcomes, particularly malocclusion. This review aimed to evaluate the association between pacifier us…
View article: Exploring the association of vitamin B12 deficiency and dental health in older adults
Exploring the association of vitamin B12 deficiency and dental health in older adults Open
Background Vitamin B12 plays a crucial role in overall health, yet its impact on dental health, particularly dental caries, remains underexplored. Older adults are at an increased risk of vitamin B12 deficiency and dental disease, but the …
View article: Unveiling the drivers of patient satisfaction in the United States hospitals: Assessing quality indicators across regions
Unveiling the drivers of patient satisfaction in the United States hospitals: Assessing quality indicators across regions Open
Introduction Patient satisfaction in the UnitedStates (U.S.) healthcare varies regionally due to cultural, socioeconomic, and infrastructure differences. The Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey …
View article: Safety of and Adverse Reactions to the COVID-19 Vaccine Among Pregnant and Breastfeeding Women
Safety of and Adverse Reactions to the COVID-19 Vaccine Among Pregnant and Breastfeeding Women Open
Objectives: This study aimed to evaluate the incidence of adverse reactions to the COVID-19 vaccine among pregnant and breastfeeding women and identify associated demographic and clinical factors. Methods: A cross-sectional study was condu…
View article: Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care
Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care Open
(1) Introduction: Human papillomavirus (HPV) is a significant public health concern associated with various cancers, including a rising incidence of oropharyngeal cancer (OPC). Despite the availability of effective vaccines targeting high-…
View article: Navigating Barriers to Dental Care for Patients with Down Syndrome: A Scoping Review of Challenges and Strategies
Navigating Barriers to Dental Care for Patients with Down Syndrome: A Scoping Review of Challenges and Strategies Open
Objective: Access to dental care is critical for overall health, yet individuals with Down Syndrome (DS) face numerous barriers, including communication difficulties, insufficiently trained professionals, and financial constraints leading …
View article: Effect of <scp>Temporary Anchorage Devices</scp> on class <scp>II</scp> anterior open bite malocclusion patient
Effect of <span>Temporary Anchorage Devices</span> on class <span>II</span> anterior open bite malocclusion patient Open
Key Clinical Message Temporary Anchorage Devices‐supported molar intrusion can be an effective non‐surgical alternative for treating Class II anterior open bite in skeletally mature patients, resulting in an improved occlusal relationship …
View article: Guided Tissue Regeneration Membranes: Review of Innovations and Applications in Immunocompromised Patients
Guided Tissue Regeneration Membranes: Review of Innovations and Applications in Immunocompromised Patients Open
Guided tissue regeneration (GTR) membranes are pivotal in regenerative medicine. While their effectiveness is established in general populations, their application in immunocompromised patients, such as those with diabetes or cancer, remai…
View article: Impact of Free Sugar Consumption on Dental Caries: A Cross-Sectional Analysis of Children in the United States
Impact of Free Sugar Consumption on Dental Caries: A Cross-Sectional Analysis of Children in the United States Open
Background/Objectives: The excessive consumption of free sugars adversely impacts health, contributing to systemic disorders and significantly increasing the risk of dental caries. Children are particularly vulnerable to dental caries due …
View article: Dasatinib and Quercetin Limit Gingival Senescence, Inflammation, and Bone Loss
Dasatinib and Quercetin Limit Gingival Senescence, Inflammation, and Bone Loss Open
Cellular senescence has emerged as one of the central hallmarks of aging and drivers of chronic comorbidities, including periodontal diseases. Senescence can also occur in younger tissues and instigate metabolic alterations and dysfunction…
View article: The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1
The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1 Open
BACKGROUNDMyotonic dystrophy type 1 (DM1) is a multisystemic, CTG repeat expansion disorder characterized by a slow, progressive decline in skeletal muscle function. A biomarker correlating RNA mis-splicing, the core pathogenic disease mec…
View article: Machine Learning for Child Oral Health: A Scoping Review
Machine Learning for Child Oral Health: A Scoping Review Open
Background: Machine learning (ML) has potential to assist dental professionals with diagnosing and predicting outcomes of oral health. Tooth decay in children is the most common chronic childhood disease and it can be prevented by early de…
View article: A Systematic Review of Stem Cell Applications in Maxillofacial Regeneration
A Systematic Review of Stem Cell Applications in Maxillofacial Regeneration Open
Introduction: Regenerative medicine is revolutionizing oral and maxillofacial surgeries with stem cells, particularly mesenchymal stem cells, for tissue and bone regeneration. Despite promising in-vitro results, human trials are limited. A…
View article: Racial Attitudes and Perceptions of Government Response during the COVID-19 Pandemic: Implications for Public Health Strategies
Racial Attitudes and Perceptions of Government Response during the COVID-19 Pandemic: Implications for Public Health Strategies Open
Background: This study explored whether opinions about the government’s role in addressing the COVID-19 pandemic vary based on demographic characteristics and racial beliefs. We hypothesized that opinions about the United States (U.S.) gov…
View article: COVID-19 Safety: Perspectives from Dental Students
COVID-19 Safety: Perspectives from Dental Students Open
Background: The coronavirus (COVID-19) pandemic created challenges for healthcare providers, especially dental professionals in practices and universities. This study investigated dental students’ concerns about COVID-19 and whether instit…
View article: Successes and Challenges in Clinical Trial Recruitment: The Experience of a New Study Team
Successes and Challenges in Clinical Trial Recruitment: The Experience of a New Study Team Open
Participant recruitment is one of the most challenging aspects of a clinical trial, directly impacting both the study’s duration and the quality of its results. Therefore, reporting successful recruitment strategies is crucial. This study …
View article: Impact of COVID-19 on Dental Students’ Mental Health Status and Perception of SARS-CoV-2 Vaccine
Impact of COVID-19 on Dental Students’ Mental Health Status and Perception of SARS-CoV-2 Vaccine Open
The COVID-19 pandemic disrupted dental education significantly, forcing adaptations in both didactic and clinical curricula. This study evaluates the impact of COVID-19 on dental students’ mental health and perceptions of the SARS-CoV-2 va…
View article: Nutritional Deficiencies and Associated Oral Health in Adolescents: A Comprehensive Scoping Review
Nutritional Deficiencies and Associated Oral Health in Adolescents: A Comprehensive Scoping Review Open
Introduction: The shift to processed foods in American diets has increased vitamin and mineral deficiencies among adolescents, impacting growth and health, often manifesting as oral lesions. This review study aimed to explore the link betw…