Explanipedia

Rapid eye movement sleep promotes fear conditioning‐induced dendritic spine elimination of layer 2/3 pyramidal neurons in the mouse motor cortex Open

Zhongyuan Li, Feilong Zhang, Yanmei Zhou, Manxia Lin, Baojun Zhang , et al. · 2025

Background Previous studies have shown that rapid eye movement (REM) sleep is important for promoting dendritic spine elimination after fear learning as well as for selectively maintaining new dendritic spines after motor learning. These R…

Liver regeneration following partial hepatectomy in hepatocellular carcinoma: not only size matters Open

Haiyi Long, Qingyu Wu, Jiayao Huang, Xian Zhong, Yuhua Xie , et al. · 2025

Background To investigate factors associated with liver regeneration capacity in patients with hepatocellular carcinoma (HCC) after liver resection. Methods A total of 123 patients with HCC who underwent liver stiffness (LS) measurement by…

Risk factors of complications after thermal ablation for hepatocellular carcinoma: the role of assessment of liver background Open

Yuhua Xie, Jing Liu, Yifan Shi, Xiaoyan Xie, Jie Yu , et al. · 2024

Objective To use an elastography technology and other clinical and radiological data for assessment of liver background and analyze risk factors of complications after thermal ablation in patients with hepatocellular carcinoma. Methods Dem…

Methodological Explainability Evaluation of an Interpretable Deep Learning Model for Post-Hepatectomy Liver Failure Prediction Incorporating Counterfactual Explanations and Layerwise Relevance Propagation: A Prospective In Silico Trial Open

Xian Zhong, Zohaib Salahuddin, Yi Chen, Henry C. Woodruff, Haiyi Long , et al. · 2024

Artificial intelligence (AI)-based decision support systems have demonstrated value in predicting post-hepatectomy liver failure (PHLF) in hepatocellular carcinoma (HCC). However, they often lack transparency, and the impact of model expla…

Liver stiffness in hepatocellular carcinoma and chronic hepatitis patients: Hepatitis B virus infection and transaminases should be considered Open

Jiayao Huang, Jianyun Peng, Haiyi Long, Xian Zhong, Yu-Hua Xie , et al. · 2024

BACKGROUND Liver condition is a crucial prognostic factor for patients with hepatocellular carcinoma (HCC), but a convenient and comprehensive method to assess liver condition is lacking. Liver stiffness (LS) measured by two-dimensional sh…

Systematic comparison of deep-learning based fusion strategies for multi-modal ultrasound in diagnosis of liver cancer Open

Ming‐De Li, Wei Li, Manxia Lin, Xin-Xin Lin, Shunro Matsumoto , et al. · 2024

Ultrasomics in liver cancer: Developing a radiomics model for differentiating intrahepatic cholangiocarcinoma from hepatocellular carcinoma using contrast-enhanced ultrasound Open

Liya Su, Ming Xu, Yanlin Chen, Manxia Lin, Xiaoyan Xie · 2024

BACKGROUND Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) represent the predominant histological types of primary liver cancer, comprising over 99% of cases. Given their differing biological behaviors, prognoses, …

Using four-point subcutaneous injection of lymphatic contrast-enhanced ultrasound to diagnose lymphedema of lower extremity Open

Jiaping Li, Jia Luo, Manying Li, Manxia Lin, Yingli Liu , et al. · 2024

This study put forward a novel four-point lymphatic-CEUS method to detect the functions of the lymphatics of lower extremities and established a lymphatic-CEUS standard for diagnosing lymphedema of lower extremities. Four-point lymphatic-C…

Contents Open

Jiaan Zhu, Qiu Li, Dean Ta, Xing Hua, Hongmei Liu , et al. · 2023

Complementary Role of CEUS and CT/MR LI-RADS for Diagnosis of Recurrent HCC Open

Mei-Qing Cheng, Hui Huang, Si‐Min Ruan, Ping Xu, Wenjuan Tong , et al. · 2023

Purpose: We retrospectively compared the diagnostic performance of contrast-enhanced ultrasonography (CEUS) and contrast-enhanced computer tomography–magnetic resonance imaging (CT/MRI) for recurrent hepatocellular carcinoma (HCC) after cu…

An Interpretable Radiomics Model Based on Two-Dimensional Shear Wave Elastography for Predicting Symptomatic Post-Hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma Open

Xian Zhong, Zohaib Salahuddin, Yi Chen, Henry C. Woodruff, Haiyi Long , et al. · 2023

Objective: The aim of this study was to develop and validate an interpretable radiomics model based on two-dimensional shear wave elastography (2D-SWE) for symptomatic post-hepatectomy liver failure (PHLF) prediction in patients undergoing…

Stiffness on shear wave elastography as a potential microenvironment biomarker for predicting tumor recurrence in HBV-related hepatocellular carcinoma Open

Xian Zhong, Haiyi Long, Lili Chen, Yuhua Xie, Yifan Shi , et al. · 2023

Combinatory local ablation and immunotherapies for hepatocellular carcinoma: Rationale, efficacy, and perspective Open

Shuling Chen, Xuezhen Zeng, Tianhong Su, Han Xiao, Manxia Lin , et al. · 2022

Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death worldwide. Local ablation, such as radiofrequency ablation, microwave ablation, cryoablation and irreversible electroporation, etc., are well established in elimin…

Identification of the origin of tumor in vein: comparison between CEUS LI-RADS v2017 and v2016 for patients at high risk Open

Wenjuan Tong, Mei‐Qing Cheng, Manxia Lin, Shunro Matsumoto, Jiamin Pan , et al. · 2022

Preoperative prognostic value of alfa-fetoprotein density in patients with hepatocellular carcinoma undergoing radiofrequency ablation Open

Bowen Zhuang, Wei Li, Bin Qiao, Nan Zhang, Manxia Lin , et al. · 2022

Serum AFP density may serve as a promising predictor of survival in patients with HCC undergoing RFA. High AFP density could identify patients who might be prone to recurrence or progression and need close surveillance.

Application of the CT/MRI LI-RADS Treatment Response Algorithm to Contrast-Enhanced Ultrasound: A Feasibility Study Open

Si‐Min Ruan, Mei‐Qing Cheng, Hui Huang, Shunro Matsumoto, Wěi Li , et al. · 2022

The CT/MRI LI-RADS TRA features were applicable to CEUS TRA for liver locoregional therapy. The CEUS TRA for liver locoregional therapy has sufficiently high specificity and PPV to diagnose the viability of lesions after ablation.

The role of neoadjuvant conventional transarterial chemoembolization with radiofrequency ablation in the treatment of recurrent hepatocellular carcinoma after initial hepatectomy with microvascular invasion Open

Zhenwei Peng, Xiaoxue Wu, Jiaping Li, Hui Pang, Yaojun Zhang , et al. · 2022

Recurrent hepatocellular carcinoma (HCC) patients with microvascular invasion (MVI)-positive primary tumor is at high risk of re-recurrence while treated with radiofrequency ablation (RFA). We aimed to investigate whether neoadjuvant conve…

Ultrasound-guided percutaneous radiofrequency ablation in treatment of neuroendocrine tumor liver metastases：a single-center experience Open

Jingzhi Huang, Baoxian Liu, Manxia Lin, Xiaoer Zhang, Yanling Zheng , et al. · 2022

RFA provides effective local tumor control with low morbidity and it can be applied repeatedly over years to control recurrence of NETLM. Patients with Ki-67 < 5% have better local tumor control with percutaneous RFA of NETLM.

Multi-Modal Fusion Strategies for Ultrasound in Diagnosis of Liver Malignant Tumor Open

Ming‐De Li, Wei Li, Manxia Lin, Shunro Matsumoto, Si‐Min Ruan , et al. · 2022

ASO Visual Abstract: Liver Stiffness Measured by Two-Dimensional Shear Wave Elastography for Predicting Symptomatic Post-Hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma Open

Haiyi Long, Xian Zhong, Liya Su, Tongyi Huang, Yu Duan , et al. · 2021

A Survival Analysis of Chinese Patients with Gastrointestinal Mucosal Melanomas: A Single-Centre Retrospective Study Open

Manxia Lin, Jiayao Huang, Junrong Chen, Xiaoying Lou, Yi Lü , et al. · 2021

Aim: Mucosal melanomas are highly malignant tumors that are of great interest for their aggressive behaviour and unfavourable prognosis, which could be the result of many reasons. In this paper, we describe a retrospective study performed …

Percutaneous thermal ablation of hepatic tumors: local control efficacy and risk factors for artificial ascites failure Open

Bowen Zhuang, Xiaohua Xie, Daopeng Yang, Manxia Lin, Wei Wang , et al. · 2021

To investigate the risk factors affecting the technical failure of artificial ascites (AA) formation and to evaluate the local control efficacy of percutaneous thermal ablation assisted by the AA for hepatic tumors. A total of 341 patients…

Safety and Local Efficacy of Laser Ablation for the Extrahepatic Metastasis of Hepatocellular Carcinoma: An Available Treatment Strategy Open

Haiyi Long, Bowen Zhuang, Guangliang Huang, Xiaoju Li, Manxia Lin , et al. · 2020

Thermal ablation plays an important role in the treatment of extrahepatic metastasis of hepatocellular carcinoma (HCC). Yet laser ablation (LA), as a safe thermal ablative modality, is less investigated in this field. In this study, the sa…

Multiple-Electrode Switching-Based Radiofrequency Ablation vs. Conventional Radiofrequency Ablation for Single Early-Stage Hepatocellular Carcinoma Ranging From 2 to 5 Cm Open

Guangliang Huang, Ming Liu, Xiaoer Zhang, Baoxian Liu, Ming Xu , et al. · 2020

Purpose: To retrospectively compare the treatment outcome of multiple-electrode switching-based radiofrequency ablation (switching RFA) and the conventional RFA for early-stage hepatocellular carcinoma (HCC). Methods: A total of 122 patien…

Deep Learning Radiomics Based on Contrast-Enhanced Ultrasound Might Optimize Curative Treatments for Very-Early or Early-Stage Hepatocellular Carcinoma Patients Open

Fei Liu, Dan Liu, Kun Wang, Xiaohua Xie, Liya Su , et al. · 2020

Background: We aimed to evaluate the performance of a deep learning (DL)-based Radiomics strategy designed for analyzing contrast-enhanced ultrasound (CEUS) to not only predict the progression-free survival (PFS) of radiofreq…

Contrast-enhanced ultrasound-guided feeding artery ablation as add-on to percutaneous radiofrequency ablation for hypervascular hepatocellular carcinoma with a modified ablative technique and tumor perfusion evaluation Open

Xiaoju Li, Ming Xu, Ming Liu, Yang Tan, Bowen Zhuang , et al. · 2020

As an add-on to conventional percutaneous RFA, tailored CEUS-guided FAA can reduce tumor perfusion and provide good local control of HCC.

Thermal ablation versus hepatic resection for the treatment of liver metastases from gastrointestinal stromal tumors: a retrospective study Open

Daopeng Yang, Bowen Zhuang, Yu-zhao Wang, Manxia Lin, Ming Xu , et al. · 2020

Objective: The study aimed to compare effectiveness and safety of thermal ablation and hepatic resection in patients with liver metastases of gastrointestinal stromal tumors (GISTs).Method: A total of 55 patients (27 in the a…

Supplementary Material for: Deep Learning Radiomics Based on Contrast-Enhanced Ultrasound Might Optimize Curative Treatments for Very-Early or Early-Stage Hepatocellular Carcinoma Patients Open

Feng Liu, D. Liu, Kun Wang, Xiaoyan Xie, Liping Su , et al. · 2020

Background: We aimed to evaluate the performance of a deep learning (DL)-based Radiomics strategy designed for analyzing contrast-enhanced ultrasound (CEUS) to not only predict the progression-free survival (PFS) of radiofreq…

Contrast-enhanced ultrasound-guided feeding artery ablation as add-on to percutaneous radiofrequency ablation for hypervascular hepatocellular carcinoma with a modified ablative technique and tumor perfusion evaluation Open

Xiaoju Li, Ming Xu, Ming Liu, Yang Tan, Bowen Zhuang , et al. · 2020

To establish a modified strategy of the feeding artery ablation (FAA) procedure as an add-on to percutaneous radiofrequency ablation (RFA) for patients with hypervascular hepatocellular carcinoma (HCC), and to evaluate the outcomes. For th…

Abstract No. 495 Automated lesion classification in patients with hepatocellular carcinoma undergoing transarterial chemoembolization: a comparison of 3D image analysis algorithms Open

Nina Tritz, S. Ghazikhanian, Julius Chapiro, Manxia Lin, C. Wang , et al. · 2019

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