Manal Mroueh
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View article: Crosstalk Between SMPDL3b and NADPH Oxidases Mediates Radiation-Induced Damage of Renal Podocytes
Crosstalk Between SMPDL3b and NADPH Oxidases Mediates Radiation-Induced Damage of Renal Podocytes Open
Patients undergoing radiotherapy (RT) for various tumors localized in the abdomen or pelvis often suffer from radiation nephrotoxicity as collateral damage. Renal podocytes are vulnerable targets for ionizing radiation and contribute to ra…
View article: Radiation-induced neuropathies in head and neck cancer: prevention and treatment modalities
Radiation-induced neuropathies in head and neck cancer: prevention and treatment modalities Open
Head and neck cancer (HNC) is the sixth most common human malignancy with a global incidence of 650,000 cases per year. Radiotherapy (RT) is commonly used as an effective therapy to treat tumours as a definitive or adjuvant treatment. Desp…
View article: Modulation of DNA Damage Response by Sphingolipid Signaling: An Interplay that Shapes Cell Fate
Modulation of DNA Damage Response by Sphingolipid Signaling: An Interplay that Shapes Cell Fate Open
Although once considered as structural components of eukaryotic biological membranes, research in the past few decades hints at a major role of bioactive sphingolipids in mediating an array of physiological processes including cell surviva…