Manale Harfouche
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View article: Epidemiology of Neisseria gonorrhoeae in South-East Asia: Systematic review, meta-analyses, and meta-regressions
Epidemiology of Neisseria gonorrhoeae in South-East Asia: Systematic review, meta-analyses, and meta-regressions Open
NG prevalence in South-East Asia is comparable to the global prevalence. The markedly high prevalence among key populations, coupled with Asia's substantial burden of gonococcal antimicrobial resistance, underscores the urgent need for tar…
View article: Estimated global and regional incidence and prevalence of herpes simplex virus infections and genital ulcer disease in 2020: mathematical modelling analyses
Estimated global and regional incidence and prevalence of herpes simplex virus infections and genital ulcer disease in 2020: mathematical modelling analyses Open
Objectives Genital herpes simplex virus (HSV) type 1 and 2 infections are lifelong and can cause symptomatic genital ulcer disease (GUD). HSV-2 almost always causes sexually transmitted genital infection, while HSV-1 mainly causes oral inf…
View article: Epidemiology of gonorrhea in countries of the Middle East and North Africa: systematic review, meta analyses, and meta regressions
Epidemiology of gonorrhea in countries of the Middle East and North Africa: systematic review, meta analyses, and meta regressions Open
Background The epidemiology of Neisseria gonorrhoeae (NG) infection in the Middle East and North Africa (MENA) region remains poorly understood, despite the global recognition of its disease burden and the growing concern regarding antimic…
View article: Epidemiology of herpes simplex virus type 1 in the United States: Systematic review, meta-analyses, and meta-regressions
Epidemiology of herpes simplex virus type 1 in the United States: Systematic review, meta-analyses, and meta-regressions Open
This study aimed to analytically describe the epidemiology of herpes simplex virus type 1 (HSV-1) infection in the United States through a systematic review and meta-analytics. We reviewed 159 publications, identifying 190 seroprevalence m…
View article: The effect of microbiome-modulating therapeutics on glucose homeostasis in metabolic syndrome: A systematic review, meta-analysis, and meta-regression of clinical trials
The effect of microbiome-modulating therapeutics on glucose homeostasis in metabolic syndrome: A systematic review, meta-analysis, and meta-regression of clinical trials Open
Probiotics, prebiotics, synbiotics and FMT supplementation improved fasting glucose and insulin in patients with MetS. Further large-scale and high-quality trials are required before potential clinical applications.
View article: Epidemiology of Trichomonas vaginalis infection in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions
Epidemiology of Trichomonas vaginalis infection in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions Open
View article: Estimated global and regional incidence and prevalence of herpes simplex virus infections and genital ulcer disease in 2020: Mathematical modeling analyses
Estimated global and regional incidence and prevalence of herpes simplex virus infections and genital ulcer disease in 2020: Mathematical modeling analyses Open
Background Genital herpes simplex virus (HSV) type 1 and 2 infections are lifelong and can cause symptomatic genital ulcer disease (GUD). HSV-2 almost always causes sexually transmitted genital infection, while HSV-1 mainly causes oral inf…
View article: Epidemiology of gonorrhoea: systematic review, meta-analyses, and meta-regressions, World Health Organization European Region, 1949 to 2021
Epidemiology of gonorrhoea: systematic review, meta-analyses, and meta-regressions, World Health Organization European Region, 1949 to 2021 Open
Background Epidemiology of Neisseria gonorrhoeae (NG) infection remains inadequately understood. Aim We aimed to characterise NG epidemiology in Europe. Methods We used Cochrane and PRISMA guidelines to systematically review, report, synth…
View article: Wearable Artificial Intelligence for Detecting Anxiety: Systematic Review and Meta-Analysis
Wearable Artificial Intelligence for Detecting Anxiety: Systematic Review and Meta-Analysis Open
Background Anxiety disorders rank among the most prevalent mental disorders worldwide. Anxiety symptoms are typically evaluated using self-assessment surveys or interview-based assessment methods conducted by clinicians, which can be subje…
View article: Epidemiology of herpes simplex virus type 1 in Canada: systematic review, meta-analyses, and meta-regressions
Epidemiology of herpes simplex virus type 1 in Canada: systematic review, meta-analyses, and meta-regressions Open
Background The objective of this study was to characterize herpes simplex virus type 1 (HSV-1) epidemiology in Canada. Methods HSV-1 publications as recent as December 6, 2021 were systematically reviewed, synthesized, and reported followi…
View article: Microbiome‐modulating nutraceuticals ameliorate dyslipidemia in type 2 diabetes: A systematic review, meta‐analysis, and meta‐regression of clinical trials
Microbiome‐modulating nutraceuticals ameliorate dyslipidemia in type 2 diabetes: A systematic review, meta‐analysis, and meta‐regression of clinical trials Open
Aims Type 2 Diabetes is intrinsically linked to cardiovascular disease (CVD) via diabetic dyslipidemia, both of which remain global health concerns with annually increasing prevalence. Given the established links between gut microbiome dys…
View article: Wearable Artificial Intelligence for Detecting Anxiety: Systematic Review and Meta-Analysis (Preprint)
Wearable Artificial Intelligence for Detecting Anxiety: Systematic Review and Meta-Analysis (Preprint) Open
BACKGROUND Anxiety disorders rank among the most prevalent mental disorders worldwide. Anxiety symptoms are typically evaluated using self-assessment surveys or interview-based assessment methods conducted by clinicians, which can be subj…
View article: Epidemiology of herpes simplex virus type 2 in the Middle East and North Africa: Systematic review, meta‐analyses, and meta‐regressions
Epidemiology of herpes simplex virus type 2 in the Middle East and North Africa: Systematic review, meta‐analyses, and meta‐regressions Open
Herpes simplex virus type 2 (HSV‐2) infection is a prevalent, sexually transmitted infection with poorly characterized prevalence in the Middle East and North Africa (MENA) region. This study characterized HSV‐2 epidemiology in MENA. HSV‐2…
View article: Epidemiology of herpes simplex virus type 1 and genital herpes in Australia and New Zealand: systematic review, meta-analyses and meta-regressions
Epidemiology of herpes simplex virus type 1 and genital herpes in Australia and New Zealand: systematic review, meta-analyses and meta-regressions Open
Herpes simplex virus type 1 (HSV-1) infection is a lifelong infection that is acquired primarily orally and during childhood. We aimed to characterise HSV-1 epidemiology in Australia and New Zealand. HSV-1-related data as recent as 6 Decem…
View article: Epidemiology of herpes simplex virus type 2 in Europe: systematic review, meta-analyses, and meta-regressions
Epidemiology of herpes simplex virus type 2 in Europe: systematic review, meta-analyses, and meta-regressions Open
View article: The effect of microbiome-modulating probiotics, prebiotics and synbiotics on glucose homeostasis in type 2 diabetes: A systematic review, meta-analysis, and meta-regression of clinical trials
The effect of microbiome-modulating probiotics, prebiotics and synbiotics on glucose homeostasis in type 2 diabetes: A systematic review, meta-analysis, and meta-regression of clinical trials Open
Data from 68 trial comparisons across 58 studies (n = 3835) revealed that, compared to placebo/control group, administration of pro/pre/synbiotics was associated with statistically significant changes in fasting plasma glucose (-12.41 mg/d…
View article: Epidemiology of Herpes Simplex Virus Type 2 in Canada, Australia, and New Zealand: Systematic Review, Meta-Analyses, and Meta-Regressions
Epidemiology of Herpes Simplex Virus Type 2 in Canada, Australia, and New Zealand: Systematic Review, Meta-Analyses, and Meta-Regressions Open
Background This study characterized the epidemiology of herpes simplex virus type 2 (HSV-2) infection in Canada, Australia, and New Zealand. Methods Cochrane and PRISMA guidelines were followed to systematically review, synthesize, and rep…
View article: P069 The epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: systematic review, meta-analyses, and meta-regressions
P069 The epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: systematic review, meta-analyses, and meta-regressions Open
Background Herpes simplex virus type 2 (HSV-2) infection is a prevalent sexually transmitted infection with a sizable disease burden that is highest in sub-Saharan Africa. This study aimed to characterize HSV-2 epidemiology in this region.…
View article: P164 The epidemiology of herpes simplex virus type 2 in Asia: a systematic review, meta-analyses, and meta-regressions
P164 The epidemiology of herpes simplex virus type 2 in Asia: a systematic review, meta-analyses, and meta-regressions Open
Background Herpes simplex virus type 2 (HSV-2) infection is a prevalent sexually transmitted infection worldwide. This systematic review aimed at characterizing HSV-2 epidemiology in Asia. Methods HSV-2 publications were systematically rev…
View article: P070 Epidemiology of herpes simplex virus type 2 in Latin America and the Caribbean: systematic review, meta-analyses, and meta-regressions
P070 Epidemiology of herpes simplex virus type 2 in Latin America and the Caribbean: systematic review, meta-analyses, and meta-regressions Open
Background Herpes simplex virus type 2 (HSV-2) infection is a sexually transmitted infection of global concern. This study aims to characterize epidemiology of herpes simplex virus type 2 (HSV-2) in Latin America and the Caribbean. Methods…
View article: Epidemiology of herpes simplex virus type 2 in Asia: A systematic review, meta-analysis, and meta-regression
Epidemiology of herpes simplex virus type 2 in Asia: A systematic review, meta-analysis, and meta-regression Open
This work was supported by the Qatar National Research Fund [NPRP 9-040-3-008] and by pilot funding from the Biomedical Research Program at Weill Cornell Medicine in Qatar.
View article: Epidemiology of herpes simplex virus type 2 in Latin America and the Caribbean: systematic review, meta-analyses and metaregressions
Epidemiology of herpes simplex virus type 2 in Latin America and the Caribbean: systematic review, meta-analyses and metaregressions Open
Objective To characterise epidemiology of herpes simplex virus type 2 (HSV-2) in Latin America and the Caribbean. Methods HSV-2 reports were systematically reviewed and synthesised, and findings were reported following Preferred Reporting …
View article: Epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: Systematic review, meta-analyses, and meta-regressions
Epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: Systematic review, meta-analyses, and meta-regressions Open
View article: The epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: systematic review, meta-analyses, and meta-regressions
The epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: systematic review, meta-analyses, and meta-regressions Open
Background Herpes simplex virus type 2 (HSV-2) infection is a prevalent sexually transmitted infection with a sizable disease burden that is highest in sub-Saharan Africa. This study aimed to characterize HSV-2 epidemiology in this region.…
View article: Epidemiology of Herpes Simplex Virus Type 2 in Asia: A Systematic Review, Meta-Analysis, and Meta-Regression
Epidemiology of Herpes Simplex Virus Type 2 in Asia: A Systematic Review, Meta-Analysis, and Meta-Regression Open
View article: Herpes simplex virus type 1 in Europe: systematic review, meta-analyses and meta-regressions
Herpes simplex virus type 1 in Europe: systematic review, meta-analyses and meta-regressions Open
Objective To describe the epidemiology of herpes simplex virus type 1 (HSV-1) in Europe. Methods We systematically reviewed HSV-1 related publications, conducted various meta-analyses and meta-regressions, assessed pooled mean seroprevalen…
View article: Seroprevalence of Herpes simplex virus types 1 and 2 in Indian and Filipino migrant populations in Qatar: a cross-sectional survey
Seroprevalence of Herpes simplex virus types 1 and 2 in Indian and Filipino migrant populations in Qatar: a cross-sectional survey Open
The seroprevalence rates of herpes simplex virus-2 in Filipino and Indian men living in Qatar were similar to those found in the Philippines and India. However, the seroprevalence of herpes simplex virus-1 in Indians, while similar to that…
View article: Herpes simplex virus: global infection prevalence and incidence estimates, 2016
Herpes simplex virus: global infection prevalence and incidence estimates, 2016 Open
An estimated half a billion people had genital infection with HSV type 2 or type 1, and several billion had oral HSV type 1 infection. Millions of people may also be at higher risk of acquiring human immunodeficiency virus (HIV), particula…
View article: Herpes simplex virus type 1 epidemiology in Africa: Systematic review, meta-analyses, and meta-regressions
Herpes simplex virus type 1 epidemiology in Africa: Systematic review, meta-analyses, and meta-regressions Open
View article: P092 Herpes simplex virus type 1 epidemiology in latin america and the caribbean: systematic review and meta-analytics
P092 Herpes simplex virus type 1 epidemiology in latin america and the caribbean: systematic review and meta-analytics Open
Background We aim to investigate the epidemiology of herpes simplex virus type 1 (HSV-1) in Latin America and the Caribbean. Methods Systematic review and meta-analytics guided by the Cochrane Collaboration Handbook and reported following …