Manika Pal Bhadra
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View article: Documentation of Indigenous Craftsmanship, Culture and Traditions of the Boat Making Craft of Uru at the Malabar Coast, India
Documentation of Indigenous Craftsmanship, Culture and Traditions of the Boat Making Craft of Uru at the Malabar Coast, India Open
India's extensive maritime history, tracing from the Indus Valley civilization to the Sangam literature, provides detailed accounts of coastal trade and boat-making activities. Additional evidence from the Jataka tales, medieval texts, tem…
View article: CCDC 2051313: Experimental Crystal Structure Determination
CCDC 2051313: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug
Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug Open
Polycomb group (PcG) proteinB lymphoma Mo-MLV insertion region 1 homolog (BMI1) is a transcriptional repressor that plays an important role in human carcinogenesis. MicroRNAs (miRNAs) are endogenous small non-coding RNAsthat implicate a ne…
View article: Two way controls of apoptotic regulators consign DmArgonaute-1 a better clasp on it
Two way controls of apoptotic regulators consign DmArgonaute-1 a better clasp on it Open
Argonaute family proteins are well conserved among all organisms. Its role in mitotic cell cycle progression and apoptotic cell elimination is poorly understood. Earlier we have established the contribution of Ago-1 in cell cycle control r…
View article: Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells
Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells Open
Glioma amplified sequence 41(GAS41) is a potent transcription factor that play a crucial role in cell proliferation and survival. In glioblastoma, the expression of GAS41 at both transcriptional and post transcriptional level needs to be t…
View article: Long non-coding RNA: Functional agent for disease traits
Long non-coding RNA: Functional agent for disease traits Open
In recent years, long non-coding RNAs (lncRNAs) have attracted the attention of researchers with their involvement in all facets of life. LncRNAs are transcripts of more than 200 nucleotides which lack defined protein coding potential. Alt…
View article: Long Noncoding RNAs are Frontier Breakthrough of RNA World and RNAi-based Gene Regulation
Long Noncoding RNAs are Frontier Breakthrough of RNA World and RNAi-based Gene Regulation Open
General complexities in versatile animals are not always proportional to their genome size. A notable example is that the salamander genome size is 15-fold larger than that of human, which mostly contains unfolded “junk DNA.” A vast portio…
View article: Correction: Fluorinated thiazolidinols cause cell death in A549 lung cancer cells via PI3K/AKT/mTOR and MAPK/ERK signalling pathways
Correction: Fluorinated thiazolidinols cause cell death in A549 lung cancer cells via PI3K/AKT/mTOR and MAPK/ERK signalling pathways Open
Correction for “Fluorinated thiazolidinols cause cell death in A549 lung cancer cells via PI3K/AKT/mTOR and MAPK/ERK signalling pathways” by Ravindra M. Kumbhare et al., Med. Chem. Commun., 2016, DOI: 10.1039/c5md00603a.
View article: Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis
Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis Open
In a previous study we reported the role of potent bisindole-PBD conjugate as an inclusion in the arsenal of breast cancer therapeutics. In breast cancer cell proliferation, PI3K/AKT/mTOR pathway plays a crucial role by prosurvival mechani…