Manali I. Patel
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View article: A mixed-methods study of communication preferences and experiences from diagnosis to death as reported by patients with advanced cancer and their family caregivers
A mixed-methods study of communication preferences and experiences from diagnosis to death as reported by patients with advanced cancer and their family caregivers Open
Critical points in the cancer journey, such as after diagnosis, during treatment decisions, and at recurrence/progression, present opportunities to support patients and family caregivers through structured follow-up visits, early palliativ…
View article: Stereotactic radiosurgery for brain metastases: evolving practice patterns from the national cancer database (2004–2020)
Stereotactic radiosurgery for brain metastases: evolving practice patterns from the national cancer database (2004–2020) Open
View article: Estimated Out-of-Pocket Costs for Patients With Common Cancers and Private Insurance
Estimated Out-of-Pocket Costs for Patients With Common Cancers and Private Insurance Open
Importance Cancer imposes a substantial economic burden on patients that may be worse in patients with higher-stage disease due to the need for more therapy. Objective To investigate the out-of-pocket costs (OOPCs) attributable to the init…
View article: 402P Impact of larger tumor lengths on survival in esophageal cancer patients treated with neoadjuvant chemoradiotherapy followed by surgery: Real-World outcomes
402P Impact of larger tumor lengths on survival in esophageal cancer patients treated with neoadjuvant chemoradiotherapy followed by surgery: Real-World outcomes Open
View article: Increasing Racial and Ethnic Diversity in Cancer Clinical Trials: An American Society of Clinical Oncology and Association of Community Cancer Centers Joint Research Statement
Increasing Racial and Ethnic Diversity in Cancer Clinical Trials: An American Society of Clinical Oncology and Association of Community Cancer Centers Joint Research Statement Open
A concerted commitment across research stakeholders is necessary to increase equity, diversity, and inclusion (EDI) and address barriers to cancer clinical trial recruitment and participation. Racial and ethnic diversity among trial partic…
View article: Do no harm: A call to action on COVID‐19 and mask requirements
Do no harm: A call to action on COVID‐19 and mask requirements Open
The COVID‐19 pandemic has challenged physicians in all specialties over the past 2 years. Continued harms caused by policies, or lack thereof, should promote those of us in the cancer field to lead by example.
View article: Increasing Racial and Ethnic Equity, Diversity, and Inclusion in Cancer Treatment Trials: Evaluation of an ASCO-Association of Community Cancer Centers Site Self-Assessment
Increasing Racial and Ethnic Equity, Diversity, and Inclusion in Cancer Treatment Trials: Evaluation of an ASCO-Association of Community Cancer Centers Site Self-Assessment Open
Clinical trial participants do not reflect the racial and ethnic diversity of people with cancer. ASCO and the Association of Community Cancer Centers collaborated on a quality improvement study to enhance racial and ethnic equity, diversi…
View article: A Mixed-Methods Study of Communication Preferences and Experiences from Diagnosis to Death as Reported by Patients with Advanced Cancer and Their Family Caregivers
A Mixed-Methods Study of Communication Preferences and Experiences from Diagnosis to Death as Reported by Patients with Advanced Cancer and Their Family Caregivers Open
View article: Immune regulatory adjuvant approach to mitigate subcutaneous immunogenicity of monoclonal antibodies
Immune regulatory adjuvant approach to mitigate subcutaneous immunogenicity of monoclonal antibodies Open
Introduction Immunogenicity continues to be a challenge for development and clinical utility of monoclonal antibodies, and there are gaps in our current ability to prevent anti-drug antibody development in a safe and antigen-specific manne…
View article: Sex‐based differences in histologic lung cancer incidence trends in the United States, 2005–2019
Sex‐based differences in histologic lung cancer incidence trends in the United States, 2005–2019 Open
Decreases in lung cancer incidence in the United States (US) have paralleled decreasing smoking prevalence for several decades; however, recent data has revealed slower declines among females than males. Sex‐based differences in histologic…
View article: “It is not the fault of the health care team - it is the way the system works”: a mixed-methods quality improvement study of patients with advanced cancer and family members reveals challenges navigating a fragmented healthcare system and the administrative and financial burdens of care
“It is not the fault of the health care team - it is the way the system works”: a mixed-methods quality improvement study of patients with advanced cancer and family members reveals challenges navigating a fragmented healthcare system and the administrative and financial burdens of care Open
Background Healthcare fragmentation and lack of care coordination are longstanding problems in cancer care. This study’s goal was to provide in-depth understanding of how the organization and fragmentation of healthcare impacts the experie…
View article: Asking the Next Generation of Electronic Patient-Reported Outcome Intervention Questions—What Components Are Needed?
Asking the Next Generation of Electronic Patient-Reported Outcome Intervention Questions—What Components Are Needed? Open
View article: Racial Disparities in Cancer Stage at Diagnosis and Survival for Adolescents and Young Adults
Racial Disparities in Cancer Stage at Diagnosis and Survival for Adolescents and Young Adults Open
Importance There are limited studies assessing stage at diagnosis and risk of death among all 5 federally defined races in the US among adolescent and young adult (AYA) patients with cancer. Objective To identify racial disparities in stag…
View article: Race and Ethnicity Representation in Phase 2/3 Oncology Clinical Trial Publications
Race and Ethnicity Representation in Phase 2/3 Oncology Clinical Trial Publications Open
Importance The five 1997 Office of Management and Budget races in the US include American Indian or Alaska Native, Asian, Black or African American, Native Hawaiian or Other Pacific Islander, and White, with Hispanic ethnicity. Despite the…
View article: Long-Term Engagement of Patients With Advanced Cancer
Long-Term Engagement of Patients With Advanced Cancer Open
Importance The long-term effect of interventions that assist patients with establishing their end-of-life care preferences among patients with cancer remain relatively unknown. Objective To evaluate the association of a long-term intervent…
View article: Coaches Activating, Reaching, and Engaging Patients to Engage in Advance Care Planning
Coaches Activating, Reaching, and Engaging Patients to Engage in Advance Care Planning Open
Importance Advance care planning (ACP) remains low among patients with advanced cancer. Multilevel interventions compared with clinician-level interventions may be more effective in improving ACP. Objective To evaluate whether a multilevel…
View article: Spending Analysis of Machine Learning–Based Communication Nudges in Oncology
Spending Analysis of Machine Learning–Based Communication Nudges in Oncology Open
A machine learning-based, behaviorally informed intervention to prompt SICs led to end-of-life savings among patients with cancer, driven by decreased systemic therapy and outpatient spending. (Funded by the Penn Center for Precision Medic…
View article: Low physical function following cancer diagnosis is associated with higher mortality risk in postmenopausal women
Low physical function following cancer diagnosis is associated with higher mortality risk in postmenopausal women Open
Background Postmenopausal women with cancer experience an accelerated physical dysfunction beyond what is expected through aging alone due to cancer and its treatments. The aim of this study was to determine whether declines in physical fu…
View article: Patient-Centered Decision-Making in Metastatic Breast Cancer Care Delivery: A Call to Action
Patient-Centered Decision-Making in Metastatic Breast Cancer Care Delivery: A Call to Action Open
atient-centered care was most recently defined by the National Academy of Sciences in 2001 as "providing care that is respectful of and responsive to individual patient preferences, needs, and values and ensuring that patient values guide …
View article: Assessment of facial golden proportions in Gujarati population – A retrospective study
Assessment of facial golden proportions in Gujarati population – A retrospective study Open
The face excels in beauty when compared with other anatomical divisions of the human beings” - Leonardo da Vinci. Golden Proportion is the mathematical ratio with has special properties, most aesthetically pleasing and aesthetic harmony. T…
View article: TECHNIQUES FOR OVERCOMING CHALLENGES TO RESEARCH WITH INDIVIDUALS NEARING THE END OF LIFE
TECHNIQUES FOR OVERCOMING CHALLENGES TO RESEARCH WITH INDIVIDUALS NEARING THE END OF LIFE Open
People living with advanced disease and nearing the end of their lives are often omitted in research on healthcare and the lifespan. This omission occurs for practical, ethical, and cultural reasons. Drawing on examples from studies on ind…
View article: The Plate Matters: Exploring the Intersection of Food Insecurity in Patients with Cancer
The Plate Matters: Exploring the Intersection of Food Insecurity in Patients with Cancer Open
This paper explores the overlooked influence of food insecurity on cancer care, its correlation with malnutrition and poor patient outcomes, and potential strategies for intervention. Food insecurity, the inconsistent access to nutritional…
View article: Novel Therapies in Cancer: Summit on Cancer Health Disparities, Keynote and Panel Discussion
Novel Therapies in Cancer: Summit on Cancer Health Disparities, Keynote and Panel Discussion Open
Molecularly-targeted therapeutics play a pivotal role in the therapeutic arena in cancer medicine, in many cases prolonging overall survival. However, despite decades since their foray into the cancer therapy armamentarium, many targeted t…
View article: Clinic-based Assessment and Support for Family Caregivers of Patients With Cancer: Results of a Feasibility Study
Clinic-based Assessment and Support for Family Caregivers of Patients With Cancer: Results of a Feasibility Study Open
Background: Cancer caregiving is burdensome with unique needs, highlighting the importance of assessing caregivers’ distress. Caregivers often accompany patients to healthcare visits, presenting an opportunity to complete distress screenin…
View article: Lay Healthcare Worker Financial Toxicity Intervention: A Pilot Financial Toxicity Screening and Referral Program
Lay Healthcare Worker Financial Toxicity Intervention: A Pilot Financial Toxicity Screening and Referral Program Open
Purpose Financial toxicity is a source of significant distress for patients with urologic cancers, yet few studies have addressed financial burden in this patient population. Methods We developed a financial toxicity screening program usin…
View article: Assessing the Needs of Those Who Serve the Underserved: A Qualitative Study among US Oncology Clinicians
Assessing the Needs of Those Who Serve the Underserved: A Qualitative Study among US Oncology Clinicians Open
Background: The American Society of Clinical Oncology established the ‘Supporting Providers Serving the Underserved’ (SUS) Task Force with a goal to develop recommendations to support cancer clinicians who deliver care for populations at r…
View article: Students Helping Students: Implementation of Elementary Math Facts Fluency Interventions by High Schoolers
Students Helping Students: Implementation of Elementary Math Facts Fluency Interventions by High Schoolers Open
Many schools face barriers that hinder access to services, including limited funding and staff trained in evidence-based interventions. In particular, rural schools must provide targeted intervention to promote academic growth and narrow a…
View article: Chewing Doma (Fermented Betel Nut): Culture versus Cancer?
Chewing Doma (Fermented Betel Nut): Culture versus Cancer? Open
Areca nut consumption is embedded in many cultures, including that of Bhutan, several parts of India, and other South Eastern countries. Traditional fermenting of areca nut results in the production of what is called doma in Bhutan. The pr…
View article: Data from Lung Cancer Incidence Trends by Histology Type among Asian American, Native Hawaiian, and Pacific Islander Populations in the United States, 1990–2010
Data from Lung Cancer Incidence Trends by Histology Type among Asian American, Native Hawaiian, and Pacific Islander Populations in the United States, 1990–2010 Open
Background: Lung cancer is one of the leading cancer sites diagnosed among Asian Americans, Pacific Islanders, and Native Hawaiians (AANHPI). To better understand the patterns of lung cancer incidence among AANHPIs, we examined the …