Explanipedia

Re: Chen et al.: High-density lipoproteins associated with age-related macular degeneration in the All of Us research program (Ophthalmology. 2025;132:684–691) Open

Anisha Kasi, John Tan, Richard B. Rosen, Avnish Deobhakta, Mandip S. Dhamoon , et al. · 2025

Development and validation of International Classification of Diseases, 9th and 10th Revision, Clinical Modification‐based algorithms to identify adult epilepsy in electronic health records Open

Hernan Nicolás Lemus, Jonathan Goldstein, Heng‐Ming Tai, Jung‐Yi Lin, Churl‐Su Kwon , et al. · 2025

Objective Electronic health records (EHRs) are increasingly used to conduct research and evaluate epilepsy quality of care. We examined the accuracy of International Classification of Diseases, 9th and 10th Revision, Clinical Modification …

Associations Between Measures of Structural Racism and Receipt of Acute Ischemic Stroke Interventions in the United States Open

Amol Mehta, Sai Polineni, Praneet Polineni, Mandip S. Dhamoon · 2025

Background Structural racism and rural/urban differences in stroke care affect care delivery and outcomes. We explored the interplay among structural racism, urbanity, and intravenous thrombolysis (tissue plasminogen activator) and endovas…

A Machine Learning Prediction Model to Identify Individuals at Risk of 5-Year Incident Stroke Based on Retinal Imaging Open

Arun Govindaiah, Tasin Bhuiyan, R. Theodore Smith, Mandip S. Dhamoon, Alauddin Bhuiyan · 2025

Stroke is a leading cause of death and disability in developed countries. We validated an AI-based prediction model for incident stroke using sensors such as fundus cameras and ophthalmoscopes for retinal images, along with socio-demograph…

Racial disparities in access to, and outcomes of, acute ischaemic stroke treatments in the USA Open

L Kiefer, David G. Daniel, Sai Polineni, Mandip S. Dhamoon · 2024

Background Racism contributes to higher comorbid risk factors and barriers to preventive measures for black Americans. Advancements in systems of care, tissue plasminogen activator (tPA) availability and endovascular thrombectomy (ET) have…

Internal Carotid Artery Stenosis and Ipsilateral Subretinal Drusenoid Deposits Open

Emanuel Mordechaev, Jason J. Jo, Samuel Mordechaev, Arun Govindaiah, Yang Fei , et al. · 2024

At least moderate ICA stenosis (≥50%-69%) is strongly associated with ipsilateral SDDs and choroidal thinning, supporting downstream ophthalmic artery and choroidal hypoperfusion from ICA stenosis as the mechanism for SDD formation. SDDs m…

Provider Care Segregation and Hospital‐Region Racial Disparities in the United States for Acute Ischemic Stroke and Endovascular Therapy Outcomes Open

David G. Daniel, Luke Maillie, Mandip S. Dhamoon · 2024

Background Reasons for racial disparities in the use and outcomes of endovascular treatment (ET) are not known. We examined patterns in care segregation for acute ischemic stroke (AIS) in the United States, and outcomes of segregation of c…

Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease Open

Richard A. Bernstein, Hooman Kamel, Christopher B. Granger, Jonathan P. Piccini, Jeffrey M. Katz , et al. · 2023

Importance The STROKE AF study found that in patients with prior ischemic stroke attributed to large-artery atherosclerotic disease (LAD) or small-vessel occlusive disease (SVD), 12% developed AF over 1 year when monitored with an insertab…

Table of Contents Open

Naaem Simaan, Jeremy Molad, Asaf Honig, Andrei Filioglo, Shlomi Peretz , et al. · 2023

Variation in US acute ischemic stroke treatment by hospital regions: limited endovascular access despite evidence Open

Laura Stein, Luke Maillie, John Erdman, Emma Loebel, Naomi Mayman , et al. · 2023

Background Although national organizations recognize the importance of regionalized acute ischemic stroke (AIS) care, data informing expansion are sparse. We assessed real-world regional variation in emergent AIS treatment, including growt…

Patterns and Outcomes of Intensive Care on Acute Ischemic Stroke Patients in the US Open

Daniel Santos, Luke Maillie, Mandip S. Dhamoon · 2023

Background: Up to 20% of acute ischemic stroke (AIS) patients may benefit from intensive care unit (ICU)-level care; however, there are few studies evaluating ICU availability for AIS. We aim to summarize the proportion of elderly AIS pati…

Intracerebral Hemorrhage in Patients with COVID-19 Infection Open

Naomi Mayman, Laura Stein, Mandip S. Dhamoon, John Liang, Alexandra S. Reynolds , et al. · 2022

Introduction: Thrombotic manifestations, such as deep vein thrombosis, pulmonary embolism, and rarely ischemic stroke, have been identified as disease complications of COVID-19. However, less is known about bleeding complications of COVID-…

Predictors of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease Open

Lee H. Schwamm, Hooman Kamel, Christopher B. Granger, Jonathan P. Piccini, Jeffrey M. Katz , et al. · 2022

Importance The Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE AF) trial found that approximately 1 in 8 patients with recent ischemic stroke attributed to large- or small-vessel disease had poststroke atrial fibrillation …

Subretinal drusenoid deposits are strongly associated with coexistent high-risk vascular diseases Open

Gerardo Ledesma‐Gil, Oscar Otero-Marquez, Sharmina Alauddin, Yuehong Tong, Katy Tai , et al. · 2022

Background/aims Demonstrate that subretinal drusenoid deposits (SDDs) in age-related macular degeneration (AMD) are linked to coexistent high-risk vascular diseases (HRVDs). Methods Cross-sectional study. Two hundred AMD subjects (aged 51–…

National Patterns and Outcomes of Neurologist Care in Acute Ischemic Stroke Open

Kate Moody, Luke Maillie, Mandip S. Dhamoon · 2022

Background & Purpose Specialist care of acute ischemic stroke patients has been associated with improved outcomes but is not well-characterized. We sought to elucidate the involvement and influence of neurologists on acute ischemic stroke …

Risk, Determinants, and Pharmacologic Treatment of Depression Following Acute Ischemic Stroke Open

Laura Stein, Naomi Mayman, Nathalie Jetté, Stanley Tuhrim, Mandip S. Dhamoon · 2022

Background and Purpose: We assessed risk and determinants of new-onset depression in acute ischemic stroke (AIS) patients of all ages and no known history of depression. Additionally, we assessed patterns of post-stroke depression (PSD) tr…

Electroencephalography at the height of a pandemic: EEG findings in patients with COVID-19 Open

Gabriela B Tantillo, Nathalie Jetté, Kapil Gururangan, Parul Agarwal, Lara Marcuse , et al. · 2022

Systemic and Genetic Risk Factors for Reticular Macular Disease and Soft Drusen in Age-Related Macular Degeneration Open

Robert J. Thomson, Joshua Chazaro, Oscar Otero-Marquez, Gerardo Ledesma‐Gil, Yuehong Tong , et al. · 2021

Purpose Soft drusen and subretinal drusenoid deposits (SDD) aka reticular macular disease (RMD) characterize two pathways to advanced age-related macular degeneration (AMD). We propose these pathways are distinct diseases, with distinct ge…

A Novel Retinal Vascular Feature and Machine Learning-based Brain White Matter Lesion Prediction Model Open

Alauddin Bhuiyan, Pallab Roy, Tasin Bhuiyan, Elsdon Storey, Walter P. Abhayaratna , et al. · 2021

White matter lesion (WML) is one of the common cerebral abnormalities, it indicates changes in the white matter of human brain and have shown significant association with stroke, dementia and deaths. Magnetic resonance imaging (MRI) of the…

Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease Open

Richard A. Bernstein, Hooman Kamel, Christopher B. Granger, Jonathan P. Piccini, Pramod Sethi , et al. · 2021

ClinicalTrials.gov Identifier: NCT02700945.

Risk Factors and Incidence of Acute Ischemic Stroke: A Comparative Study Between Young Adults and Older Adults Open

Urvish Patel, Mihir Dave, Anusha Lekshminarayanan, Preeti Malik, Matthew DeMasi , et al. · 2021

Introduction Approximately 5-10% of strokes occur in adults of less than 45 years of age. The rising prevalence of stroke risk factors may increase stroke rates in young adults (YA). We aimed to compare risk factors and outcomes of acute i…

The emerging association between COVID-19 and acute stroke Open

Laura Stein, Naomi Mayman, Mandip S. Dhamoon, Johanna T Fifi · 2021

Recovery From Mobility Limitation in Middle-Aged African Americans: The Jackson Heart Study Open

Michelle C. Odden, Kendra D. Sims, Roland J. Thorpe, Mario Sims, Mandip S. Dhamoon , et al. · 2020

Background Despite evidence that African Americans shoulder a high burden of mobility limitation, little is known about factors associated with recovery. Method Participants from the Jackson Heart Study underwent 3 in-person exams from 200…

Characteristics and Outcomes of Hospitalizations and Readmissions for Opioid Dependence and Overdose: Nationally Representative Data Open

Sarah Grzebinski, Laura Stein, Mandip S. Dhamoon · 2020

Background Despite the increasing rates of morbidity, mortality, and costs from the opioid addiction crisis, there is a paucity of literature on nationwide patterns of opioid abuse and dependence admissions and readmissions. We sought to i…

Correction to: Pre-existing cerebrovascular disease and poor outcomes of COVID-19 hospitalized patients: a meta-analysis Open

Urvish Patel, Preeti Malik, Dhaivat Shah, Achint Patel, Mandip S. Dhamoon , et al. · 2020

Emergent Large Vessel Occlusion Stroke During New York City's COVID-19 Outbreak: Clinical Characteristics and Paraclinical Findings. Open

Shahram Majidi, Johanna T Fifi, Travis R. Ladner, Jacques Lara‐Reyna, Kurt Yaeger , et al. · 2020

More than half of the ELVO stroke patients during the peak time of the New York City's COVID-19 outbreak were COVID-19 positive, and those patients with COVID-19 were younger, more likely to be male, and less likely to be White. Our findin…

Readmissions for Depression and Suicide Attempt following Stroke and Myocardial Infarction Open

Laura Stein, Alana Kornspun, John Erdman, Mandip S. Dhamoon · 2020

Background and Purpose: Rates of depression after ischemic stroke (IS) and myocardial infarction (MI) are significantly higher than in the general population and associated with morbidity and mortality. There is a lack of nat…

Early epidemiological indicators, outcomes, and interventions of COVID-19 pandemic: A systematic review Open

Urvish Patel, Preeti Malik, Deep Mehta, Dhaivat Shah, Raveena Kelkar , et al. · 2020

A collective approach undertaken by a responsible government, wise strategy implementation and a receptive population may help contain the spread of COVID-19 outbreak. Close monitoring of predictive models of such indicators in the highly …

History of Stroke Is Independently Associated With In-Hospital Death in Patients With COVID-19 Open

Benjamin Kummer, Eyal Klang, Laura Stein, Mandip S. Dhamoon, Nathalie Jetté · 2020

Background and Purpose: In December 2019, an outbreak of severe acute respiratory syndrome coronavirus causing coronavirus disease 2019 (COVID-19) occurred in China, and evolved into a worldwide pandemic. It remains unclear whether the his…

Pre-existing cerebrovascular disease and poor outcomes of COVID-19 hospitalized patients: a meta-analysis Open

Urvish Patel, Preeti Malik, Dhaivat Shah, Achint Patel, Mandip S. Dhamoon , et al. · 2020

Mandip S. Dhamoon YOU? Author Swipe