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View article: Organophosphate pesticide metabolite concentrations in a pregnancy cohort: daily variability, and predictors of exposure
Organophosphate pesticide metabolite concentrations in a pregnancy cohort: daily variability, and predictors of exposure Open
Organophosphates (OP) are commonly used agricultural pesticides. In 2009-2010, 80 pregnant women were recruited from Ottawa, Canada for the Plastics and Personal-care Product use in Pregnancy (P4) Study. A subset (n = 25) collected multipl…
View article: Arsenic, Cadmium, Lead, Mercury, and PFAS Exposure During Pregnancy or Lactation and Respective Concentrations in Human Milk: Systematic Review
Arsenic, Cadmium, Lead, Mercury, and PFAS Exposure During Pregnancy or Lactation and Respective Concentrations in Human Milk: Systematic Review Open
Contaminant exposure during pregnancy or lactation may result in contaminant transfer into human milk (HM). This systematic review (PROSPERO# CRD42024530326) assessed relationships between arsenic, cadmium, lead, mercury, and per- and poly…
View article: Assessment of arsenic, cadmium, lead, mercury, and per- and polyfluoroalkyl substances concentrations in human milk and infant formula in the United States: a systematic review
Assessment of arsenic, cadmium, lead, mercury, and per- and polyfluoroalkyl substances concentrations in human milk and infant formula in the United States: a systematic review Open
In published, peer-reviewed United States studies, PFOA and PFOS were detected in HM; PFAS were largely undetected in IF. There was a paucity of contemporary evidence for arsenic, cadmium, lead, and mercury in HM or IF in the United States…
View article: Exposure to Metal Mixtures and Childhood Adiposity: An Examination of Periods of Heightened Susceptibility Between Gestation and Late Childhood
Exposure to Metal Mixtures and Childhood Adiposity: An Examination of Periods of Heightened Susceptibility Between Gestation and Late Childhood Open
Introduction Childhood obesity is a public health concern. Studies have investigated the effects of metal mixtures on childhood obesity but none have identified periods of heightened susceptibility of exposure. We identified the periods by…
View article: Contaminant Composition of Human Milk in the US: A Systematic Review
Contaminant Composition of Human Milk in the US: A Systematic Review Open
View article: Infant Exposure to Heavy Metals and PFAS in the United States: A Systematic Review
Infant Exposure to Heavy Metals and PFAS in the United States: A Systematic Review Open
View article: Contaminant Composition of Infant Formulas in the US: A Systematic Review
Contaminant Composition of Infant Formulas in the US: A Systematic Review Open
View article: Bioavailability of Contaminants in Human Milk and Infant Formula When Consumed by the Infant: A Systematic Review
Bioavailability of Contaminants in Human Milk and Infant Formula When Consumed by the Infant: A Systematic Review Open
View article: Contaminant Exposure During Pregnancy and Lactation and Contaminant Concentrations in Human Milk: A Systematic Review
Contaminant Exposure During Pregnancy and Lactation and Contaminant Concentrations in Human Milk: A Systematic Review Open
View article: Associations of prenatal glyphosate exposure with child neurodevelopment in a Canadian pregnancy cohort study
Associations of prenatal glyphosate exposure with child neurodevelopment in a Canadian pregnancy cohort study Open
In this primarily urban cohort of Canadian mother-child pairs, prenatal glyphosate and AMPA exposure were not significantly associated with child neurodevelopment. Further evaluation of glyphosate as a potential developmental neurotoxicant…
View article: Prenatal Concentrations of Perfluoroalkyl Substances and Maternal Beta Cell Function at 7 to 9 Years of Follow-Up
Prenatal Concentrations of Perfluoroalkyl Substances and Maternal Beta Cell Function at 7 to 9 Years of Follow-Up Open
Context Epidemiological evidence regarding prenatal per- and polyfluoroalkyl substance (PFAS) exposure and long-term maternal metabolic health outcomes is lacking. Objective Quantify associations between prenatal PFAS concentrations and ma…
View article: The Association Between Pregnancy Complications and Long-term Maternal Cardiometabolic Health in the MIREC Cohort Study
The Association Between Pregnancy Complications and Long-term Maternal Cardiometabolic Health in the MIREC Cohort Study Open
Context During pregnancy, women who experience certain pregnancy complications show elevations in biomarkers of inflammation and insulin resistance; however, few studies have examined these cardiometabolic biomarkers in the decade followin…
View article: Vitamin D and Toxic Metals in Pregnancy - a Biological Perspective
Vitamin D and Toxic Metals in Pregnancy - a Biological Perspective Open
View article: Personal care product use and per- and polyfluoroalkyl substances in pregnant and lactating people in the Maternal-Infant Research on Environmental Chemicals study
Personal care product use and per- and polyfluoroalkyl substances in pregnant and lactating people in the Maternal-Infant Research on Environmental Chemicals study Open
View article: Personal care product use and per- and polyfluoroalkyl substances in pregnant and lactating people in the Maternal-Infant Research on Environmental Chemicals study
Personal care product use and per- and polyfluoroalkyl substances in pregnant and lactating people in the Maternal-Infant Research on Environmental Chemicals study Open
Our results show that PCP use may be a modifiable source of PFAS exposure in pregnant and lactating populations. These results along with growing scientific evidence can help inform PFAS regulation and guide individual choices to reduce PF…
View article: Concentrations and predictors of select nutrients in Canadian human milk samples from the Maternal-Infant Research on Environmental Chemicals pregnancy cohort
Concentrations and predictors of select nutrients in Canadian human milk samples from the Maternal-Infant Research on Environmental Chemicals pregnancy cohort Open
HM mineral concentrations from this study meet the methodological inclusion criteria for updating nutrient databank values and dietary reference intakes. Consideration of factors such as diet, skin color, and BMI will be important for sele…
View article: Gestational urinary concentrations of glyphosate and aminomethylphosphonic acid in relation to preterm birth: the MIREC study
Gestational urinary concentrations of glyphosate and aminomethylphosphonic acid in relation to preterm birth: the MIREC study Open
View article: Prenatal glyphosate and AMPA exposure and child neurodevelopment in a Canadian birth cohort study
Prenatal glyphosate and AMPA exposure and child neurodevelopment in a Canadian birth cohort study Open
View article: Association between prenatal plasma concentrations of perfluoroalkyl substances and long-term maternal metabolic health
Association between prenatal plasma concentrations of perfluoroalkyl substances and long-term maternal metabolic health Open
View article: Air pollutants and plasma total folate among pregnant women in Canada, 2008-2011
Air pollutants and plasma total folate among pregnant women in Canada, 2008-2011 Open
View article: Vitamin D and Toxic Metals in Pregnancy - a Biological Perspective
Vitamin D and Toxic Metals in Pregnancy - a Biological Perspective Open
Purpose of Review To discuss the potential biological mechanisms between vitamin D and toxic metals and summarize epidemiological studies examining this association in pregnant women. Recent Findings We identified four plausible mechanisms…
View article: Prenatal Exposure to Air Pollution and Respiratory Distress in Term Newborns: Results from the MIREC Prospective Pregnancy Cohort
Prenatal Exposure to Air Pollution and Respiratory Distress in Term Newborns: Results from the MIREC Prospective Pregnancy Cohort Open
Prenatal exposures to increased the risk of severe respiratory distress among term newborns. These findings support the development and prioritization of public health and prenatal care strategies to increase awareness and minimize prenat…
View article: Prenatal Exposure to Per- and Polyfluoroalkyl Substances and its Association with Neurobehavioral and Social Development During Childhood
Prenatal Exposure to Per- and Polyfluoroalkyl Substances and its Association with Neurobehavioral and Social Development During Childhood Open
View article: <scp>Cohort profile update</scp>: The Canadian <scp>Maternal–Infant</scp> Research on Environmental Chemicals Child Development study (<scp>MIREC‐CD PLUS</scp>)
<span>Cohort profile update</span>: The Canadian <span>Maternal–Infant</span> Research on Environmental Chemicals Child Development study (<span>MIREC‐CD PLUS</span>) Open
Background The pan‐Canadian Maternal–Infant Research on Environmental Chemicals (MIREC) study was established to determine whether maternal environmental chemical exposures were associated with adverse pregnancy outcomes in 2001 pregnant w…
View article: Personal care product use and perfluoroalkyl substances in pregnant and postpartum women and adolescents in the United States and Canada
Personal care product use and perfluoroalkyl substances in pregnant and postpartum women and adolescents in the United States and Canada Open
BACKGROUND AND AIM: Perfluoroalkyl substances (PFAS) are ubiquitous chemicals routinely detected in personal care products (PCPs), associated with numerous adverse health outcomes. Few studies have quantified the contribution of PCPs on PF…
View article: A descriptive analysis of first trimester urinary concentrations of 14 bisphenol analogues in the MIREC Canadian pregnancy cohort
A descriptive analysis of first trimester urinary concentrations of 14 bisphenol analogues in the MIREC Canadian pregnancy cohort Open
BP 4,4', DHDPE, BPE, BPF, and BPS were highly detected in 1st trimester urine samples in this large pan-Canadian pregnancy cohort. This suggests widespread exposure to these analogues around 2008-2011 and warrants further invest…
View article: Measurement of 24 phthalate metabolites in 1st trimester urine samples: The MIREC study
Measurement of 24 phthalate metabolites in 1st trimester urine samples: The MIREC study Open
Phthalates are non-persistent chemicals measured as metabolites in urine. Over time, new metabolites have been identified. In the original Maternal-Infant Research on Environmental Chemicals (MIREC) study (2008-2011), we measured 11 phthal…
View article: Prenatal and concurrent blood mercury concentrations and associations with IQ in canadian preschool children
Prenatal and concurrent blood mercury concentrations and associations with IQ in canadian preschool children Open
Prenatal exposure to low levels of Hg was associated with lower PIQ scores in male children with low prenatal fish intake. Positive associations between cord and child blood Hg concentrations and IQ were primarily observed in female childr…
View article: Prenatal exposure to legacy PFAS and neurodevelopment in preschool-aged Canadian children: The MIREC cohort
Prenatal exposure to legacy PFAS and neurodevelopment in preschool-aged Canadian children: The MIREC cohort Open
View article: Descriptive analysis of organophosphate ester metabolites in a pan-Canadian pregnancy cohort
Descriptive analysis of organophosphate ester metabolites in a pan-Canadian pregnancy cohort Open
Organophosphate esters (OPEs) are widely used in numerous consumer products for their flame retardant and plasticizing properties. Despite potential widespread exposure, biomonitoring data during critical windows of development are scarce …