Maneesh N. Singh
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View article: Infrared spectroscopy as a new approach for early fabry disease screening: a pilot study
Infrared spectroscopy as a new approach for early fabry disease screening: a pilot study Open
View article: Infrared spectroscopy as a new approach for early Fabry disease screening: a pilot study
Infrared spectroscopy as a new approach for early Fabry disease screening: a pilot study Open
Background Fabry disease (FD) is a rare X-linked lysosomal storage disorder marked by alpha-galactosidase-A (α-Gal A) deficiency, caused by pathogenic mutations in the GLA gene, resulting in the accumulation of glycosphingolipids within ly…
View article: Indian Voting System with Borda count method
Indian Voting System with Borda count method Open
India is a democratic country where it is "ruled by the people for the people."Althoughsome circumstances attract attention whether the above statement is true.We can only see the 2014 Loksabha elections where Narendra Modi became the Prim…
View article: Near-Infrared Spectroscopy with Supervised Machine Learning as a Screening Tool for Neutropenia
Near-Infrared Spectroscopy with Supervised Machine Learning as a Screening Tool for Neutropenia Open
The use of non-invasive tools in conjunction with artificial intelligence (AI) to detect diseases has the potential to revolutionize healthcare. Near-infrared spectroscopy (NIR) is a technology that can be used to analyze biological sample…
View article: Point-of-Care Disease Screening in Primary Care Using Saliva: A Biospectroscopy Approach for Lung Cancer and Prostate Cancer
Point-of-Care Disease Screening in Primary Care Using Saliva: A Biospectroscopy Approach for Lung Cancer and Prostate Cancer Open
Saliva is a largely unexplored liquid biopsy that can be readily obtained noninvasively. Not dissimilar to blood plasma or serum, it contains a vast array of bioconstituents that may be associated with the absence or presence of a disease …
View article: Infrared spectroscopy as a new approach for Fabry disease screening
Infrared spectroscopy as a new approach for Fabry disease screening Open
Background Fabry disease (FD) is a rare X-linked lysosomal storage disorder marked by alpha-galactosidase-A (α-Gal A) deficiency, caused by pathogenic mutations in the GLA gene resulting in the accumulation of glycosphingolipids inside lys…
View article: ATR-FTIR Spectroscopy with Chemometrics for Analysis of Saliva Samples Obtained in a Lung-Cancer-Screening Programme: Application of Swabs as a Paradigm for High Throughput in a Clinical Setting
ATR-FTIR Spectroscopy with Chemometrics for Analysis of Saliva Samples Obtained in a Lung-Cancer-Screening Programme: Application of Swabs as a Paradigm for High Throughput in a Clinical Setting Open
There is an increasing need for inexpensive and rapid screening tests in point-of-care clinical oncology settings. Herein, we develop a swab “dip” test in saliva obtained from consenting patients participating in a lung-cancer-screening pr…
View article: Detection and quantification using ATR-FTIR spectroscopy of whey protein concentrate adulteration with wheat flour
Detection and quantification using ATR-FTIR spectroscopy of whey protein concentrate adulteration with wheat flour Open
Expensive and time-consuming methods are currently used to identify manipulated whey protein concentrate (WPC). We tested the application of attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy to detect and quant…
View article: MALDI(+) FT-ICR Mass Spectrometry (MS) Combined with Machine Learning toward Saliva-Based Diagnostic Screening for COVID-19
MALDI(+) FT-ICR Mass Spectrometry (MS) Combined with Machine Learning toward Saliva-Based Diagnostic Screening for COVID-19 Open
Rapid identification of existing respiratory viruses in biological samples is of utmost importance in strategies to combat pandemics. Inputting MALDI FT-ICR MS (matrix-assisted laser desorption/ionization Fourier-transform ion cyclotron re…
View article: Ultra-rapid on-site detection of SARS-CoV-2 infection using simple ATR-FTIR spectroscopy and analysis algorithm: high sensitivity and specificity
Ultra-rapid on-site detection of SARS-CoV-2 infection using simple ATR-FTIR spectroscopy and analysis algorithm: high sensitivity and specificity Open
There is an urgent need for ultra-rapid testing regimens to detect the SARS-CoV-2 [Severe Acute Respiratory Syndrome Coronavirus 2] virus infections in real-time within seconds to stop its spread. Current testing approaches for this RNA vi…
View article: Tutorial: multivariate classification for vibrational spectroscopy in biological samples
Tutorial: multivariate classification for vibrational spectroscopy in biological samples Open
Vibrational spectroscopy techniques, such as Fourier-transform infrared (FTIR) and Raman spectroscopy, have been successful methods for studying the interaction of light with biological materials and facilitating novel cell biology analysi…