Manikandan Ekambaram
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View article: A scoping review of hydroxyapatite-modified glass ionomer cements used for restorative dentistry
A scoping review of hydroxyapatite-modified glass ionomer cements used for restorative dentistry Open
This scoping review provides a valuable overview of HA modified-GICs research. Additionally, it identifies potential research areas that can be investigated further to enhance properties of HA modified-GICs for clinical application.
View article: Advanced Laboratory Assessments in Caries Mineralization Research: A Review
Advanced Laboratory Assessments in Caries Mineralization Research: A Review Open
Dental caries is characterized by the dynamic processes of demineralization and remineralization. Recent advancements in cariology research have introduced sophisticated techniques such as nanoindentation, nano-computed tomography, optical…
View article: Development and characterisation of a novel antimicrobial peptide GA-C16G2 targeting Streptococcus mutans
Development and characterisation of a novel antimicrobial peptide GA-C16G2 targeting Streptococcus mutans Open
GA-C16G2 offers a novel therapeutic approach for targeted prevention and treatment of dental caries.
View article: Sustainability of Improvement in Oral‐Health‐Related Quality of Life Following Dental Treatment Under General Anaesthetic: The Role of Family Functioning
Sustainability of Improvement in Oral‐Health‐Related Quality of Life Following Dental Treatment Under General Anaesthetic: The Role of Family Functioning Open
Background Early childhood caries (ECC) impacts both children and their families. Aim To characterise improvement in oral‐health‐related quality of life (OHRQoL) among young children undergoing treatment for ECC under general anaesthesia (…
View article: Acid‐Resistant Glass Ionomer Cements: An Assessment of Their Mechanical Properties, Fluoride Ion Release and Protection to Surrounding Tooth Surfaces From Acid Challenges
Acid‐Resistant Glass Ionomer Cements: An Assessment of Their Mechanical Properties, Fluoride Ion Release and Protection to Surrounding Tooth Surfaces From Acid Challenges Open
New acid‐resistant glass ionomer cements (GIC) claim to be able to withstand acidic conditions while also protecting surrounding tooth structures and preserving function. Currently, there are only a few studies that assessed mechanical pro…
View article: In Vitro Models Used in Cariology Mineralisation Research—A Review of the Literature
In Vitro Models Used in Cariology Mineralisation Research—A Review of the Literature Open
Background: Dental caries remains a significant global health problem. One of the fundamental mechanisms underlying the development and progression of dental caries is the dynamic process of demineralisation/remineralisation. In vitro mode…
View article: Dental Applications of Ion-Substituted Hydroxyapatite: A Review of the Literature
Dental Applications of Ion-Substituted Hydroxyapatite: A Review of the Literature Open
Hydroxyapatite (HA) forms an essential constituent of human teeth and bone. Its distinctive characteristic features, such as bioactivity and osteoconductivity, make it an ideal candidate to be used as an implant coating in restorative dent…
View article: A scoping review of the influence of clinical contaminants on bond strength in direct adhesive restorative procedures
A scoping review of the influence of clinical contaminants on bond strength in direct adhesive restorative procedures Open
This scoping review provides a valuable overview of the range of potential clinical contaminants that can influence the bond strength between different interfaces in direct adhesive restorative procedures. Additionally, it identifies poten…
View article: Remineralization potential of dentifrices with calcium sodium phosphosilicate and functionalized tri‐calcium phosphate in the deeper incipient carious lesions: An in vitro study
Remineralization potential of dentifrices with calcium sodium phosphosilicate and functionalized tri‐calcium phosphate in the deeper incipient carious lesions: An in vitro study Open
Objectives This study evaluated the remineralization potential of calcium sodium phosphosilicate and functionalized tri‐calcium phosphate (f‐TCP) dentifrices in deeper incipient carious lesions (ICLs). Materials and Methods Artificial ICLs…
View article: A Comparison of the Enamel Remineralisation Potential of Self-Assembling Peptides
A Comparison of the Enamel Remineralisation Potential of Self-Assembling Peptides Open
P26 and P11-4 SAPs are more effective than 5% NaF varnish in remineralising the depth of EECLs.
View article: Potential Beneficial Effects of Hydroxyapatite Nanoparticles on Caries Lesions In Vitro—A Review of the Literature
Potential Beneficial Effects of Hydroxyapatite Nanoparticles on Caries Lesions In Vitro—A Review of the Literature Open
Dental caries is one of the most common human diseases which can occur in both primary and permanent dentitions throughout the life of an individual. Hydroxyapatite is the major inorganic component of human teeth, consequently, nanosized h…
View article: A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel Open
Aprismatic enamel and prismatic enamel have similar mineral loss in acetic acid while prismatic enamel showed more mineral loss compared to aprismatic enamel in lactic acid.
View article: Does Early Childhood Caries Increase Caries Development among School Children and Adolescents? A Systematic Review and Meta-Analysis
Does Early Childhood Caries Increase Caries Development among School Children and Adolescents? A Systematic Review and Meta-Analysis Open
The aim of this paper is to systematically review the literature to determine whether early childhood caries (ECC) is significantly associated with caries development in permanent teeth among school children and adolescents, and to identif…
View article: Effect of sleep on development of early childhood caries: a systematic review
Effect of sleep on development of early childhood caries: a systematic review Open
Purpose To investigate the impact of sleep on the development of early childhood caries (ECC). Methods Seven electronic databases and grey literature were searched with various keyword combinations. Two reviewers independently selected stu…
View article: Combined effect of arginine and fluoride on the growth of Lactobacillus rhamnosus GG
Combined effect of arginine and fluoride on the growth of Lactobacillus rhamnosus GG Open
View article: Supplementary Material for: Glass Ionomer Sealant versus Fluoride Varnish Application to Prevent Occlusal Caries in Primary Second Molars among Preschool Children: A Randomized Controlled Trial
Supplementary Material for: Glass Ionomer Sealant versus Fluoride Varnish Application to Prevent Occlusal Caries in Primary Second Molars among Preschool Children: A Randomized Controlled Trial Open
Fissure sealant is a recommended preventive measure on permanent molars, but its efficacy on primary molars in preschool children is still in doubt. Sodium fluoride varnish (NaFV) enhances remineralization and is effective in preventing ca…
View article: Glass Ionomer Sealant versus Fluoride Varnish Application to Prevent Occlusal Caries in Primary Second Molars among Preschool Children: A Randomized Controlled Trial
Glass Ionomer Sealant versus Fluoride Varnish Application to Prevent Occlusal Caries in Primary Second Molars among Preschool Children: A Randomized Controlled Trial Open
Fissure sealant is a recommended preventive measure on permanent molars, but its efficacy on primary molars in preschool children is still in doubt. Sodium fluoride varnish (NaFV) enhances remineralization and is effective in preventing ca…
View article: Physicochemical Characteristics of Arginine Enriched NaF Varnish: An In Vitro Study
Physicochemical Characteristics of Arginine Enriched NaF Varnish: An In Vitro Study Open
The in vitro study objectives were to investigate the effect of arginine (Arg) incorporation in a 5% sodium fluoride (NaF) varnish on its physical and chemical properties including F/Arg release. Six experimental formulations were prepared…
View article: Inter-method reliability for determining total and soluble fluorides in child low-fluoride formula dentifrices
Inter-method reliability for determining total and soluble fluorides in child low-fluoride formula dentifrices Open
View article: Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation
Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation Open
Dental caries or tooth decay is a preventable and multifactorial disease that affects billions of people globally and is a particular concern in younger populations. This decay arises from acid demineralisation of tooth enamel resulting in…
View article: Synbiotics in caries prevention: A scoping review
Synbiotics in caries prevention: A scoping review Open
The scoping review aimed to examine the evidence on the role of synbiotics in caries prevention. PubMed, SCOPUS, and Web of Science databases search were performed. Any in vitro study, clinical trial, systematic review with/without meta-an…
View article: Effect of a novel synbiotic on Streptococcus mutans
Effect of a novel synbiotic on Streptococcus mutans Open
We examined the effect of L-arginine - (i) on the growth of L. rhamnosus GG (LrG) and (ii) combined LrG synbiotic on the growth of cariogenic S. mutans . Viability of LrG was assessed using MTT/XTT assays, confocal imaging with ADS activit…
View article: A comparison of visual identification of dental radiographic and nonradiographic images using eye tracking technology
A comparison of visual identification of dental radiographic and nonradiographic images using eye tracking technology Open
Objectives Eye tracking has been used in medical radiology to understand observers' gaze patterns during radiological diagnosis. This study examines the visual identification ability of junior hospital dental officers (JHDOs) and dental su…
View article: The combined antimicrobial effect of arginine and fluoride toothpaste
The combined antimicrobial effect of arginine and fluoride toothpaste Open
View article: Corrigendum to: Effectiveness of self-applied topical fluorides against enamel white spot lesions from multi-bracketed fixed orthodontic treatment: a systematic review
Corrigendum to: Effectiveness of self-applied topical fluorides against enamel white spot lesions from multi-bracketed fixed orthodontic treatment: a systematic review Open
View article: Knowledge, perceptions, and clinical experiences on molar incisor hypomineralization among dental care providers in Hong Kong
Knowledge, perceptions, and clinical experiences on molar incisor hypomineralization among dental care providers in Hong Kong Open
Continuing education on MIH is needed to assure that the highest quality of evidence-based care is given to patients with MIH. Dissemination of latest best evidence on MIH, especially to GDPs, will assure that the condition is accurately d…
View article: Prevalence, characteristic features, and complications associated with the occurrence of unerupted permanent incisors
Prevalence, characteristic features, and complications associated with the occurrence of unerupted permanent incisors Open
This study examined the prevalence, characteristic features, and complications associated with the occurrence of unerupted permanent incisors among children and adolescents attending a university dental teaching hospital. A retrospective r…
View article: Comparison of deproteinization agents on bonding to developmentally hypomineralized enamel
Comparison of deproteinization agents on bonding to developmentally hypomineralized enamel Open
View article: Molar incisor hypomineralization: current research evidences
Molar incisor hypomineralization: current research evidences Open
Objective:The aim of this literature review was to study the underlying mechanisms of the association between periodontal disease and prostate cancer.Methods: This study was literature review study, pubmed searching was used to find scient…
View article: Bonding to hypomineralized enamel – A systematic review
Bonding to hypomineralized enamel – A systematic review Open