Veera M. Rajagopal
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View article: Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients Open
To our knowledge, this is the first GWAS of FS, and our results support a genetic basis of FS. Future large-scale genetic research studies are needed to corroborate these findings and identify genetic variants associated with FS.
View article: Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk Open
View article: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk Open
View article: Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals
Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals Open
View article: A deep catalogue of protein-coding variation in 983,578 individuals
A deep catalogue of protein-coding variation in 983,578 individuals Open
Rare coding variants that substantially affect function provide insights into the biology of a gene 1–3 . However, ascertaining the frequency of such variants requires large sample sizes 4–8 . Here we present a catalogue of human protein-c…
View article: Polygenic Risk of Mental Disorders and Subject-Specific School Grades
Polygenic Risk of Mental Disorders and Subject-Specific School Grades Open
View article: Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications Open
As recreational use of cannabis is being decriminalized in many places and medical use widely sanctioned, there are growing concerns about increases in cannabis use disorder (CanUD), which is associated with numerous medical comorbidities.…
View article: A large meta-analysis identifies genes associated with anterior uveitis
A large meta-analysis identifies genes associated with anterior uveitis Open
View article: Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses
Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses Open
View article: Rare coding variants in CHRNB2 reduce the likelihood of smoking
Rare coding variants in CHRNB2 reduce the likelihood of smoking Open
View article: A deep catalog of protein-coding variation in 985,830 individuals
A deep catalog of protein-coding variation in 985,830 individuals Open
Coding variants that have significant impact on function can provide insights into the biology of a gene but are typically rare in the population. Identifying and ascertaining the frequency of such rare variants requires very large sample …
View article: Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains Open
View article: Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes
Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes Open
View article: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains Open
View article: Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity
Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity Open
View article: Common and rare variant associations with clonal haematopoiesis phenotypes
Common and rare variant associations with clonal haematopoiesis phenotypes Open
View article: Rare coding variants in<i>CHRNB2</i>reduce the likelihood of smoking
Rare coding variants in<i>CHRNB2</i>reduce the likelihood of smoking Open
Human genetic studies of smoking behavior have been so far largely limited to common variations. Studying rare coding variants has potential to identify new drug targets and refine our understanding of the mechanisms of known targets. We p…
View article: Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people
Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people Open
The use of spoken and written language is a fundamental human capacity. Individual differences in reading- and language-related skills are influenced by genetic variation, with twin-based heritability estimates of 30 to 80% depending on th…
View article: Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder
Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder Open
View article: Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci
Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci Open
View article: Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry
Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry Open
Background Despite the large toll of opioid use disorder (OUD), genome-wide association studies (GWAS) of OUD to date have yielded few susceptibility loci. Methods We performed a large-scale GWAS of OUD in individuals of European (EUR) and…
View article: Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample
Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample Open
In this large, population-based GWEIS, we did not find any replicable hits for interaction. Future gene-by-stress research in depression should focus on establishing even larger collaborative GWEISs to attain sufficient power.
View article: Genome-wide association analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people
Genome-wide association analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people Open
The use of spoken and written language is a capacity that is unique to humans. Individual differences in reading- and language-related skills are influenced by genetic variation, with twin-based heritability estimates of 30-80%, depending …
View article: Exome sequencing and analysis of 454,787 UK Biobank participants
Exome sequencing and analysis of 454,787 UK Biobank participants Open
A major goal in human genetics is to use natural variation to understand the phenotypic consequences of altering each protein-coding gene in the genome. Here we used exome sequencing 1 to explore protein-altering variants and their consequ…
View article: Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample
Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample Open
Researchers have long investigated a hypothesized interaction between genetic risk and stressful life events in the etiology of depression, but studies on the topic have yielded inconsistent results. We conducted a genome-wide environment …
View article: Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention deficit hyperactivity disorder
Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention deficit hyperactivity disorder Open
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder, with onset in childhood (“childhood ADHD”), and around two thirds of affected individuals will continue to have ADHD symptoms in adulthood (“persistent ADHD”…
View article: Genetic analyses identify widespread sex-differential participation bias
Genetic analyses identify widespread sex-differential participation bias Open
View article: Ethnobotanical indices on wound healing medicinal plants in the Arjuna River of Virudhunagar District in Tamil Nadu, Southern India
Ethnobotanical indices on wound healing medicinal plants in the Arjuna River of Virudhunagar District in Tamil Nadu, Southern India Open
Shanmugam S, Rajagopal V, Balamurugan S, Muthupandi CP, Eswaran VM, Raveendraretnam K, Rajendran K. 2021. Ethnobotanical indices on wound healing medicinal plants in the Arjuna River of Virudhunagar District in Tamil Nadu, Southern India. …
View article: Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder Open
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21566-w
View article: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder Open