Explanipedia

Situs inversus totalis in a case of Joubert syndrome Open

Manish Taneja, Vijay Ganesh, B. Sangeetha · 2025

Joubert syndrome (JS) is an uncommon genetic condition distinguished by a unique midbrain-hindbrain abnormality known as the ‘molar tooth sign (MTS)’. Classic JS is defined by three main findings: the MTS is a specific cerebellum and brain…

Unlocking the potential of gold nanoparticles as a game-changer in the fight against hepatocellular carcinoma Open

Sarmistha Saha, Manish Taneja, Sarvesh Dubey, Alok Bharadwaj · 2025

According to research, hepatocellular carcinoma (HCC), ranks third globally in terms of cause of death and is the fifth most common type of cancer overall. Finding novel means of diagnosis and treatment is therefore crucial. The use of nan…

Lentil hypersensitivity pneumonitis as a masquerader in an infant with recurrent pneumonia Open

Sangeetha Balasubramania, Vijay Ganesh, Amit Pathania, Manish Taneja · 2024

Lentils appear to be the most frequent legume associated with childhood allergies in the Mediterranean and India. The prevalence of food-allergic diseases in childhood is around 3%, with a range between 1.4-4% for common allergens. The Pap…

Spontaneous intracranial hypotension causing headache in a child: A case report and overview of CT myelogram technique Open

Rhea Taneja, Timothy K.Y. Lee, Manish Taneja · 2023

Background: Spontaneous Intracranial Hypotension (SIH) is a well-known condition, generally presenting as a postural headache in individuals between the ages of 40 and 50 years. Cases within the paediatric population are rare, and may requ…

Iliac Interventions Open

Eelin Tan, Manish Taneja, José Wiley, Cornelia Rivera, Apoorva Gogna · 2022

Clinical characteristics & outcome of SARS-CoV-2 infected neonates presenting to paediatric emergency Open

Jogender Kumar, Praveen Kumar, Shiv Sajan Saini, Venkataseshan Sundaram, Kanya Mukhopadhyay , et al. · 2022

Background & objectives Data on neonatal COVID-19 are limited to the immediate postnatal period, with a primary focus on vertical transmission in inborn infants. This study was aimed to assess the characteristics and outcome of COVID-19 in…

149 Emergency Clot Retrieval and Stenting for Posterior Circulation Stroke Open

Karan Daga, Mehtab Ahmad, Manish Taneja · 2021

The current literature regarding the morphology and presentations of strokes due to basilar artery stenosis/occlusion is limited. This pathology is a rare cause of stroke and its management is not clearly decided in guidelines or published…

148 Acute Renal Infarcts from Spontaneous Intra-Renal Dissection Open

Karan Daga, Beelee Chua, Manish Taneja · 2021

Spontaneous renal artery dissection and acute renal infarcts are rare occurrences and often misdiagnosed in clinical practice. We present four male patients, between 30-50 years of age, who have no underlying cardiac conditions, hypertensi…

Severe neonatal pulmonary artery hypertension rescued with vasopressin Open

Ankit Ranjan, Venkataseshan Sundaram, Manish Taneja, Sourabh Dutta · 2021

An inborn term neonate weighing 2600 g developed meconium aspiration syndrome at birth. Baby had respiratory failure requiring high-frequency oscillatory ventilation support at 15 hours of life. He additionally developed hypotension with l…

Small Intracranial Aneurysms and Subarachnoid Hemorrhage: Is the Size Criterion for Risk of Rupture Relevant? Open

Karan Daga, Manish Taneja, Narayanaswamy Venketasubramanian · 2020

The current understanding is that small intracranial aneurysms (<7 mm) are not at a significant risk for rupture. However, there have been several published series of rupture and subarachnoid hemorrhage from aneurysms <5 mm. Thre…

Transcranial Color-Coded Duplex Ultrasound for Assessing Cerebrovascular Reserve in Intracranial Dissection with Aneurysm Open

Narayanaswamy Venketasubramanian, Andrew Eik Hock Tan, Wee Thong Neo, Manish Taneja · 2020

Intracranial artery dissection (IAD) is an uncommon cause of cerebral ischemia. It may lead to symptoms due to rupture of subadventitial aneurysms or thromboembolism from subintimal disruption. Severe stenosis may lead to reduced cerebrova…

Isolated Focal Basilar Artery Stenosis with Acute Stroke Treated with Emergency Thrombectomy and Stenting Open

Karan Daga, Manish Taneja, Mohammad Taqueer Ahmad, Narayanaswamy Venketasubramanian · 2020

Strokes due to basilar artery (BA) stenosis/occlusion are devastating. As it is an uncommon cause of stroke, its optimal management is not clearly defined. We present the case of a 68-year-old male with a background history of hypertension…

Limb-Shaking Transient Ischemic Attacks in a Patient with Previous Bilateral Neck Irradiation: The Role of Collateral Flow Open

Chai-Hoon Nowel Tan, Manish Taneja, Narayanaswamy Venketasubramanian · 2020

Nasopharyngeal carcinoma (NPC) is commonly treated with bilateral neck radiation, which is closely associated with the complication of carotid-occlusive disease. This leads to cerebral hemodynamic compromise and possible ischemic stroke. A…

Transcranial Doppler in the Detection and Management of Arterial Vasospasm after Aneurysmal Subarachnoid Haemorrhage Open

Narayanaswamy Venketasubramanian, Manish Taneja, David Kim Seng Choy · 2020

Delayed cerebral ischaemia (DCI) and cerebral infarction is a much-feared complication of aneurysmal subarachnoid haemorrhage (aSAH). It has been largely attributed to focal hypoperfusion from reversible cerebral arterial narrowing, “vasos…

Renal nutcracker syndrome in a young lady: unusual findings and endovascular management Open

Manish Taneja, Benjamin Chua, Kanika Daga · 2018

Nutcracker syndrome (NCS) is caused by compression of left renal vein (LRV), usually between the aorta and the superior mesenteric artery (SMA). This can lead to obstruction of flow into the inferior vena cava and secondary left renal veno…

Unusual Clinical Presentation of Nutcracker Phenomenon Open

Ai Peng Tan, Benjamin SY Chua, Kok Bin Lim, Manish Taneja · 2017

Chimney stent grafts in the era of custom-made devices: A comparative review of complex abdominal aortic aneurysm stenting Open

BenjaminSY Chua, ShaunQW Lee, JackKian Ch'ng, Manish Taneja · 2017

Introduction: Surgical treatment of abdominal aortic aneurysms (AAA) has evolved over the past 15 years. Fenestrated endovascular of AAAs (FEVAR) and Chimney endovascular of AAA (Chimney EVAR) are techniques that have been introduced and u…

Dose optimization of ceftriaxone-vancomycin combination using fractional inhibitory concentration kinetics in resistant bacteria Open

V D Sharma, Aman Singla, Manu Chaudhary, Mukesh Kumar, Anuj Bhatnagar , et al. · 2016

The notorious Staphylococcus aureus resistant strains with ever changing resistance patterns have limited treatment options and have led to substantial number of deaths. Almost dried antibiotic pipeline has led us to look into combinations…

DOSE OPTIMIZATION OF CEFTRIAXONE-SULBACTAM COMBINATION IN ADULTS USING IN VITRO SYSTEMS, PK/PD MODELING AND STOCHASTIC SIMULATIONS APPROACHES Open

V D Sharma, Aman Singla, Manu Chaudhary, Manish Taneja · 2016

Objective: To optimize the dosage regimen of fixed-dose combination (FDC) of ceftriaxone/sulbactam (2/1 w/w) using in vitro system, pharmacokinetic/pharmacodynamic (PK/PD) modeling and Monte-Carlo simulations (MCS). Methods: One comp…

Population Pharmacokinetics of Fixed Dose Combination of Ceftriaxone and Sulbactam in Healthy and Infected Subjects Open

V D Sharma, Aman Singla, Manu Chaudhary, Manish Taneja · 2015

Identification of Family Risk Factors of Obesity in Urban Adolescents of North India Open

Mohinder Singh, SuryaKant Mathur, Manish Taneja, Baljeet Maini · 2015

Background: Obesity in rising in the adolescent population of India. The third National Family Health Survey (NFHS-3) national family health survey (NFHS-3) of India revealed increasing obesity in north Indian states more than other parts …

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