Explanipedia

EFFECT OF YOGA BREAK ON EMOTIONAL INTELLIGENCE OF OFFICE WORKERS OF UNIVERSITIES AND COLLEGES Open

Vikram Singh, Richa Malhotra, Manjari Joshi, Dileep Kumar Tiwari, Navdeep Joshi , et al. · 2024

Mental health problems impact working professionals regardless of whether they are employed in the commercial sector or the public sector. Emotional troubles might arise from a discrepancy between our expectations and reality. Factors such…

The impact of heterotopic ossification prophylaxis after surgical fixation of acetabular fractures: national treatment patterns and related outcomes Open

Adam Boissonneault, Nathan O Hara, David Pogorzelski, Lucas S. Marchand, Thomas F. Higgins , et al. · 2023

Local administration of vancomycin powder in orthopaedic fracture surgery: current practice and trends Open

Lucas S. Marchand, Sheila Sprague, Nathan N. O’Hara, Chuan Silvia Li, Robert V. OʼToole , et al. · 2023

Objectives: Surgical site infections in orthopaedic trauma are a significant problem with meaningful patient and health care system–level consequences. Direct application of antibiotics to the surgical field has many potential benefits in …

Association of Patient-Level and Hospital-Level Factors With Timely Fracture Care by Race Open

Ida Leah Gitajn, Paul M. Werth, Eseosa Fernandes, Sheila Sprague, Nathan N. O’Hara , et al. · 2022

Importance Racial disparities in treatment benchmarks have been documented among older patients with hip fractures. However, these studies were limited to patient-level evaluations. Objective To assess whether disparities in meeting fractu…

A pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solutions in open fractures (Aqueous-PREP): statistical analysis plan Open

Nathan N. O’Hara, Diane Heels‐Ansdell, Sofia Bzovsky, Shannon Dodds, Lehana Thabane , et al. · 2022

Association of COVID-19 With Achieving Time-to-Surgery Benchmarks in Patients With Musculoskeletal Trauma Open

Ida Leah Gitajn, Paul M. Werth, Sheila Sprague, Nathan N. O’Hara, Gregory Della Rocca , et al. · 2021

In this cohort study, there was no association between meeting time-to-surgery benchmarks in either open fracture or closed femur/hip fracture during the COVID-19 pandemic compared with before the pandemic. This is counter to concerns that…

Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials Open

Guillermo Pechero, Branden Pfaff, Mayank Rao, David Pogorzelski, Paula McKay , et al. · 2021

Patient and stakeholder engagement learnings: PREP-IT as a case study Open

Michelle Medeiros, T. Rosie Love, Gerard P. Slobogean, Sheila Sprague, Eleanor M. Perfetto , et al. · 2021

Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures Open

Robert V. OʼToole, Manjari Joshi, Anthony R. Carlini, Clinton K. Murray, Lauren Allen , et al. · 2021

ClinicalTrials.gov Identifier: NCT02227446.

Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial Open

David Pogorzelski, Uyen Nguyen, Paula McKay, Lehana Thabane, Megan Camara , et al. · 2021

Implementing a sampling strategy in the PREPARE trial has helped to limit the number of missed eligible patients. This sampling strategy represents a simple, easy to use tool for managing work flow at clinical sites and maintaining the int…

Evaluation of Linezolid Pharmacokinetics in Critically Ill Obese Patients with Severe Skin and Soft Tissue Infections Open

Alison Blackman, Praneeth Jarugula, David P. Nicolau, Sai Ho Chui, Manjari Joshi , et al. · 2020

Linezolid standard dosing is fixed at 600 mg every 12 h (q12h) for adults. Literature suggests critically ill, obese patients require higher doses.

Correction to: Cluster identification, selection, and description in Cluster randomized crossover trials: the PREP-IT trials Open

Sheila Sprague, Taryn Scott, Shannon Dodds, David Pogorzelski, Paula McKay , et al. · 2020

Effectiveness of Iodophor vs Chlorhexidine Solutions for Surgical Site Infections and Unplanned Reoperations for Patients Who Underwent Fracture Repair Open

Gerard P. Slobogean, Sheila Sprague, Jeffrey Wells, Mohit Bhandari, Jean-Claude D’Alleyrand , et al. · 2020

ClinicalTrials.gov Identifiers: NCT03385304 and NCT03523962.

Effect of Extended Prophylactic Antibiotic Duration in the Treatment of Open Fracture Wounds Differs by Level of Contamination Open

Christina A. Stennett, Nathan N. O’Hara, Sheila Sprague, Brad Petrisor, Kyle J. Jeray , et al. · 2020

Objective: To determine the association between prophylactic antibiotic duration after the definitive wound closure of an open fracture and deep surgical site infection (SSI). Design: Retrospective cohort study. Setting: 41 clinical sites …

Adjuvant antibiotic‐loaded bone cement: Concerns with current use and research to make it work Open

Edward M. Schwarz, A. C. McLaren, Thomas P. Sculco, Barry D. Brause, Mathias P. Bostrom , et al. · 2020

Antibiotic‐loaded bone cement (ALBC) is broadly used to treat orthopaedic infections based on the rationale that high‐dose local delivery is essential to eradicate biofilm‐associated bacteria. However, ALBC formulations are empirically bas…

450. Evaluation of Linezolid Pharmacokinetics in Obese Patients with Severe Skin and Soft-Tissue Infections Open

Alison Blackman, Praneeth Jarugula, David P. Nicolau, Sai Ho Chui, Manjari Joshi , et al. · 2019

Background Linezolid is an oxazolidinone antibiotic with broad activity against Gram-positive bacteria and serves as an option for treating severe skin and soft-tissue infections (SSTIs). Adult FDA-labeled dosing is fixed at 600 mg IV/PO t…

Issue Information ‐ Editorial Board and TOC Open

Edward M. Schwarz, Javad Parvizi, Thorsten Gehrke, Amiethab A. Aiyer, Andrew K. Battenberg , et al. · 2019

Rest of World), €1154 (Europe), £914 (UK

2018 international consensus meeting on musculoskeletal infection: Summary from the biofilm workgroup and consensus on biofilm related musculoskeletal infections Open

Kordo Saeed, A. C. McLaren, Edward M. Schwarz, Valentin Antoci, William V. Arnold , et al. · 2019

Biofilm‐associated implant‐related bone and joint infections are clinically important due to the extensive morbidity, cost of care and socioeconomic burden that they cause. Research in the field of biofilms has expanded in the past two dec…

Necrotizing fasciitis caused by<i>Kocuria rosea</i>in an immunocompromised patient Open

Manjari Joshi, Paul R. Cardinal, Sharon Henry · 2018

This case report describes an immunocompromised patient with a skin boil that progressed to necrotizing fasciitis. The aim of this brief report is to raise awareness regarding necrotizing soft tissue infections caused by an unusual organis…

Acute Transverse Myelitis Associated with Salmonella Bacteremia: A Case Report Open

Mary Richert, Hillary Hosier, Adam S. Weltz, Eric S. Wise, Manjari Joshi , et al. · 2016

BACKGROUND Acute transverse myelitis (ATM) is an uncommon and often overlooked complication of certain bacterial and viral infections that can have a rapid onset and result in severe neurological deficits. CASE REPORT This case report desc…

ICE volume 37 issue 2 Cover and Front matter Open

Duc B. Nguyen, Jennifer Gutowski, Margherita Ghiselli, Tabitha Cheng, Shadia Bel Hamdounia , et al. · 2016

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A Multicenter Longitudinal Study of Hospital-Onset Bacteremia: Time for a New Quality Outcome Measure? Open

Clare Rock, Kerri A. Thom, Anthony D. Harris, Shanahan Li, Daniel M. Morgan , et al. · 2015

BACKGROUND Central-line–associated bloodstream infection (CLABSI) rate is an important quality measure, but it suffers from subjectivity and interrater variability, and decreasing national CLABSI rates may compromise its power to discrimin…

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