Manjun Luo
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View article: The association between early pregnancy maternal lipid indicators with gestational diabetes mellitus and pre-eclampsia
The association between early pregnancy maternal lipid indicators with gestational diabetes mellitus and pre-eclampsia Open
The relationship between early pregnancy lipid indicators and gestational diabetes mellitus (GDM) or pre-eclampsia (PE) remains incompletely elucidated. This prospective cohort study explored the associations between seven lipid indicators…
View article: Vitamin A, Vitamin D, Iron, and Zinc in Relation to Anemia Risk: Observational Evidence and Mendelian Randomization
Vitamin A, Vitamin D, Iron, and Zinc in Relation to Anemia Risk: Observational Evidence and Mendelian Randomization Open
Background: Anemia remains an important public health problem worldwide. Investigating the potential influencing factors of anemia can provide a reference for improving anemia status. This study aimed to identify factors influencing anemia…
View article: The impact of maternal health and lifestyle on low birth weight: a prospective cohort study
The impact of maternal health and lifestyle on low birth weight: a prospective cohort study Open
Background To explore maternal pregestational and periconceptional factors associated with low birth weight in offspring and inform the development of targeted interventions. Methods A prospective birth cohort involving 34,104 pregnant wom…
View article: Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population
Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population Open
Registration number: ChiCTR1800016635; Registration time: 14/06/2018.
View article: [A case-control study on the associations of parental smoking and alcohol consumption during the periconceptional period and their interactions with risk of congenital heart disease in offspring].
[A case-control study on the associations of parental smoking and alcohol consumption during the periconceptional period and their interactions with risk of congenital heart disease in offspring]. Open
Parental smoking and alcohol consumption during the periconceptional period are associated with the occurrence of CHD in offspring, and there is a cumulative effect on CHD risk, suggesting that reducing tobacco and alcohol exposure during …
View article: [Maternal <i>MTR</i> gene polymorphisms and their interactions with periconceptional folic acid supplementation in relation to offspring ventricular septal defects].
[Maternal <i>MTR</i> gene polymorphisms and their interactions with periconceptional folic acid supplementation in relation to offspring ventricular septal defects]. Open
Maternal MTR gene polymorphisms significantly correlate with the incidence of VSD in offspring. Mothers with variations at rs6668344 can decrease the susceptibility to VSD in their offspring by supplementing with folic acid during t…
View article: Association of Maternal Dietary Habits and Infant MTHFR Gene Polymorphisms with Ventricular Septal Defect in Offspring: A Case–Control Study
Association of Maternal Dietary Habits and Infant MTHFR Gene Polymorphisms with Ventricular Septal Defect in Offspring: A Case–Control Study Open
This study aimed to explore the association of maternal diet, infant MTHFR gene polymorphisms, and their interactions with the risk of ventricular septal defects (VSDs). This case–control study recruited 448 mothers of VSD children and 620…
View article: Type 2 Diabetes, Glycemic Traits, Structural Brain Capacity and Cognitive Function: A Mendelian Randomization Analyses
Type 2 Diabetes, Glycemic Traits, Structural Brain Capacity and Cognitive Function: A Mendelian Randomization Analyses Open
View article: Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population
Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population Open
Background Although many studies shown that the risk of congenital heart disease (CHD) was closely related to genetic and environmental factors, the exact mechanism was still unclear. This study was to assess the association of maternal fo…
View article: Association of Maternal Folate Intake and Offspring MTHFD1 and MTHFD2 Genes with Congenital Heart Disease
Association of Maternal Folate Intake and Offspring MTHFD1 and MTHFD2 Genes with Congenital Heart Disease Open
Existing evidence supported that congenital heart defect (CHD) was associated with a combination of environmental and genetic factors. Based on this, this study aimed at assessing the association of maternal folic acid supplementation (FAS…
View article: Association between air pollution and primary liver cancer in European and east Asian populations: a Mendelian randomization study
Association between air pollution and primary liver cancer in European and east Asian populations: a Mendelian randomization study Open
Purpose The incidence of primary liver cancer is increasing year by year, with environmental factors playing a non-negligible role. At present, many studies are still disputing whether air pollution is associated with primary liver cancer …
View article: Fertility intentions to have a second or third child among the childbearing-age population in Central China under China’s three-child policy: A cross-sectional study
Fertility intentions to have a second or third child among the childbearing-age population in Central China under China’s three-child policy: A cross-sectional study Open
The general prevalence of the second and third birth intention of the childbearing-age population in Central China is not high. To increase the birth rate, it is necessary to create a favourable fertility context and offer supportive measu…
View article: Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization study
Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization study Open
Objective The real causal relationship between human gut microbiota and T1D remains unclear and difficult to establish. Herein, we adopted a two-sample bidirectional mendelian randomization (MR) study to evaluate the causality between gut …
View article: Effect of the interaction between advanced maternal age and pre-pregnancy BMI on pre-eclampsia and GDM in Central China
Effect of the interaction between advanced maternal age and pre-pregnancy BMI on pre-eclampsia and GDM in Central China Open
Introduction To investigate the independent and combined effects of advanced maternal age and pre-pregnancy body mass index (BMI) on the risk of pre-eclampsia and gestational diabetes mellitus (GDM). Research design and methods Logistic re…
View article: Parental pre-pregnancy body mass index and risk of low birth weight in offspring: A prospective cohort study in central China
Parental pre-pregnancy body mass index and risk of low birth weight in offspring: A prospective cohort study in central China Open
Background Low birth weight (LBW) is one of the most common adverse pregnancy outcomes. Previous studies have consistently shown that maternal body mass index (BMI) status before and during pregnancy is associated with LBW. However, previo…
View article: Association and Interaction Effect of BHMT Gene Polymorphisms and Maternal Dietary Habits with Ventricular Septal Defect in Offspring
Association and Interaction Effect of BHMT Gene Polymorphisms and Maternal Dietary Habits with Ventricular Septal Defect in Offspring Open
This study attempted to learn the association between maternal betaine-homocysteine methyltransferase (BHMT) gene polymorphisms, maternal dietary habits, and their interactions with the risk of ventricular septal defects (VSD) in offspring…
View article: BHMT gene SNP.sav
BHMT gene SNP.sav Open
Genomic DNA was extracted from blood cell sample mentioned earlier using the QIAamp DNA Mini Kit (Qiagen, Valencia, CA, USA) according to the manufacturer’s standard protocol and dissolved in sterile TBE bufer. The polymorphisms of BHMT an…