Manliu Wang
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View article: Origin of poorly galactosylated IgA1 other than mucosa: a viewpoint from a report on patient with IgA vasculitis
Origin of poorly galactosylated IgA1 other than mucosa: a viewpoint from a report on patient with IgA vasculitis Open
Patients presenting monoclonal gammopathy of renal significance (MGRS) and IgA vasculitis collectively have rarely been reported. This study reports one patient with monoclonal IgA and λ, and with IgA positive-mesangial proliferative glome…
View article: Complement Activation Is Associated With Crescents in IgA Nephropathy
Complement Activation Is Associated With Crescents in IgA Nephropathy Open
Introduction Crescents, especially those found at a percentage greater than 50%, are often associated with rapid progression of kidney disease in IgA nephropathy (IgAN). The mechanism of crescents forming in IgAN is still unclear. In this …
View article: Secondary IgA Nephropathy Shares the Same Immune Features With Primary IgA Nephropathy
Secondary IgA Nephropathy Shares the Same Immune Features With Primary IgA Nephropathy Open
Our study strongly suggests that secondary IgAN shares a similar galactose-deficient IgA1-oriented pathogenesis with primary IgAN.