Manoj K. Pal
YOU?
Author Swipe
View article: Chip-scale optical detection of lung cancer with engineered photodetector based on distributed semiconductor heterojunctions
Chip-scale optical detection of lung cancer with engineered photodetector based on distributed semiconductor heterojunctions Open
View article: Computational drug discovery of phytochemical alkaloids targeting the NACHT/PYD domain in the NLRP3 inflammasome
Computational drug discovery of phytochemical alkaloids targeting the NACHT/PYD domain in the NLRP3 inflammasome Open
View article: Antibacterial and Antiprotease activities of fermented barnyard millet (Echinochloa frumentacea) protein hydrolysate
Antibacterial and Antiprotease activities of fermented barnyard millet (Echinochloa frumentacea) protein hydrolysate Open
View article: Pro-neurogenic potential of blood cells cultured in autologous plasma
Pro-neurogenic potential of blood cells cultured in autologous plasma Open
The lack of effective stem cell protocols for generating personalized neurovascular niches poses a critical challenge in precision medicine. While iPSC-based methods are explored, their clinical use is hindered by high costs, long timeline…
View article: Preliminary isolation and biochemical characterization of plant growth promoting rhizobacteria from Curcuma longa from the high-altitude region of Uttarakhand
Preliminary isolation and biochemical characterization of plant growth promoting rhizobacteria from Curcuma longa from the high-altitude region of Uttarakhand Open
Curcuma longa L. (common name: turmeric) is a medicinal herb with a rhizome and belongs to the Zingiberaceae family. The Indian subcontinent widely cultivates it, making it a significant commercial crop. Plant growth-promoting rhizobacteri…
View article: A Fast and Reliable Approach to Protein Structure Prediction Using K-Mer Matching and Modeller
A Fast and Reliable Approach to Protein Structure Prediction Using K-Mer Matching and Modeller Open
View article: A Structural Proteomics Exploration of Synphilin-1 and Alpha-Synuclein Interaction in Pathogenesis of Parkinson’s Disease
A Structural Proteomics Exploration of Synphilin-1 and Alpha-Synuclein Interaction in Pathogenesis of Parkinson’s Disease Open
Pathological significance of interaction of Synphilin-1 with mutated alpha-synuclein is well known to have serious consequences in causing the formation of inclusion bodies that are linked to Parkinson’s disease (PD). Information extracted…
View article: Building Neurovascular tissue from autologous blood for modeling brain activity
Building Neurovascular tissue from autologous blood for modeling brain activity Open
There are no faithful individualized stem cell-based bioengineered neuro-vascularized models that can recapitulate the physiological hemodynamic phenomenon of neuro-vascular coupling (NVC)-the principal behind BOLD (blood oxygen level-depe…
View article: Real-time Data Pipeline Optimization using AI-driven Resource Allocation
Real-time Data Pipeline Optimization using AI-driven Resource Allocation Open
This paper discusses an AI approach to improve how data is processed in real time by adjusting the way resources are given to distributed systems. Our framework adapts and changes the amount of CPU, available memory, and network use to hit…
View article: In silico Targeting of the NACHT/PYD Domain in NLRP3 Inflammasome Using Phytochemical Alkaloids: A Computational Drug Discovery Approach
In silico Targeting of the NACHT/PYD Domain in NLRP3 Inflammasome Using Phytochemical Alkaloids: A Computational Drug Discovery Approach Open
Background The NLRP3 inflammasome plays a pivotal role in the innate immune system, orchestrating the activation of caspase-1 and the release of proinflammatory cytokines IL-1β and IL-18 in reaction to microbial infections and cellular dam…
View article: In-Silico Studies Targeting the Drug-Resistant Outer Membrane Proteins of E. Coli with Possible Monoterpenes from Essential Oils
In-Silico Studies Targeting the Drug-Resistant Outer Membrane Proteins of E. Coli with Possible Monoterpenes from Essential Oils Open
View article: CCDC 2260302: Experimental Crystal Structure Determination
CCDC 2260302: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Rhizobacterial mediated interactions in Curcuma longa for plant growth and enhanced crop productivity: a systematic review
Rhizobacterial mediated interactions in Curcuma longa for plant growth and enhanced crop productivity: a systematic review Open
Turmeric ( Curcuma longa L.), a significant commercial crop of the Indian subcontinent is widely used as a condiment, natural dye, and as a cure for different ailments. Various bioactive compounds such as turmerones and curcuminoids have b…
View article: Electroactive microbe communication: A crucial aspect for energy generation in bio-electrochemical systems
Electroactive microbe communication: A crucial aspect for energy generation in bio-electrochemical systems Open
View article: Authors’ Response to Letter on “Down but Not Out: Vasectomy Is Faring Poorly Almost Everywhere—We Can Do Better to Make It a True Method Option”
Authors’ Response to Letter on “Down but Not Out: Vasectomy Is Faring Poorly Almost Everywhere—We Can Do Better to Make It a True Method Option” Open
View article: Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development
Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development Open
ARX788 is an anti-HER2 antibody drug conjugate (ADC) developed using Ambrx proprietary Engineered Precision Biologics technology. The manufacturing process of ARX788 has been optimized during the course of early to late-phase clinical deve…
View article: Mathematical Models of Fluid Dynamics and Their Numerical Solutions
Mathematical Models of Fluid Dynamics and Their Numerical Solutions Open
Fluid dynamics is a crucial field of study in both physics and engineering, as it deals with the movement of fluids and their interactions with surrounding forces and boundaries. The behavior of fluids in motion is governed by complex math…
View article: Solutions of Computing Problems Using Differential Equations
Solutions of Computing Problems Using Differential Equations Open
Differential equations are a very much fundamental tool for the purpose of modeling dynamic systems across that of the science and engineering disciplines. This particular paper explores the application of ordinary as well as the partial d…
View article: Application of sequence semantic and integrated cellular geography approach to study alternative biogenesis of exonic circular RNA
Application of sequence semantic and integrated cellular geography approach to study alternative biogenesis of exonic circular RNA Open
Background Concurrent existence of lncRNA and circular RNA at both nucleus and cytosol within a cell at different proportions is well reported. Previous studies showed that circular RNAs are synthesized in nucleus followed by transportatio…
View article: Analytical Comparability to Evaluate Impact of Manufacturing Changes of ARX788, an Anti-HER2 ADC in Late-Stage Clinical Development
Analytical Comparability to Evaluate Impact of Manufacturing Changes of ARX788, an Anti-HER2 ADC in Late-Stage Clinical Development Open
ARX788 is an anti-HER2 antibody drug conjugate (ADC) developed using Ambrx proprietary Engineered Precision Biologics technology. The manufacturing process of ARX788 has been optimized during the course of early to late-phase clinical deve…
View article: Down But Not Out: Vasectomy Is Faring Poorly Almost Everywhere—We Can Do Better To Make It A True Method Option
Down But Not Out: Vasectomy Is Faring Poorly Almost Everywhere—We Can Do Better To Make It A True Method Option Open
Vasectomy use is surprisingly low globally and declining. Use remains negligible in almost all LMICs, reflecting low demand and program priority. For vasectomy to become an accessible, rights-based option, program efforts need to be holist…
View article: CCDC 2180268: Experimental Crystal Structure Determination
CCDC 2180268: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2180267: Experimental Crystal Structure Determination
CCDC 2180267: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2180270: Experimental Crystal Structure Determination
CCDC 2180270: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2180271: Experimental Crystal Structure Determination
CCDC 2180271: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2180266: Experimental Crystal Structure Determination
CCDC 2180266: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2180269: Experimental Crystal Structure Determination
CCDC 2180269: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2026986: Experimental Crystal Structure Determination
CCDC 2026986: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Application of sequence semantic and integrated cellular geography approach to study biogenesis of exonic circular RNA
Application of sequence semantic and integrated cellular geography approach to study biogenesis of exonic circular RNA Open
Background Concurrent existence of lncRNA and circular RNA at both nucleus and cytosol within a cell at different proportion is well reported. Secondly, information on genes transcribing both circular and lncRNAs along with total number of…
View article: CCDC 1982011: Experimental Crystal Structure Determination
CCDC 1982011: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …