Manoj K. Sarma
YOU?
Author Swipe
View article: Lipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-Abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus
Lipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-Abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus Open
Background/Objectives: This study evaluated metabolites and lipid composition in the calf muscles of Type 2 diabetes mellitus (T2DM) patients and age-matched healthy controls using multi-dimensional MR spectroscopic imaging. We also explor…
View article: Lipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus
Lipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus Open
This study evaluated metabolites and lipid composition in the calf muscles of Type 2 Diabetes Mellitus (T2DM) patients and age-matched healthy controls using multi-dimensional MR Spectroscopic Imaging. We also explored the association betw…
View article: Neurocognitive Functioning is Impaired in Perinatally HIV-Infected Youth
Neurocognitive Functioning is Impaired in Perinatally HIV-Infected Youth Open
Background The present study examined neurocognitive differences between Perinatally HIV (PHIV)-infected-youth and age and gender matched healthy controls. Despite early, long-term anti-viral treatment (ART), significant neurocognitive def…
View article: 3T <scp><sup>31</sup>P</scp>/<scp><sup>1</sup>H</scp> calf muscle coil for <scp><sup>1</sup>H</scp> and <scp><sup>31</sup>P MRI</scp>/<scp>MRS</scp> integrated with <scp>NIRS</scp> data acquisition
3T <span><sup>31</sup>P</span>/<span><sup>1</sup>H</span> calf muscle coil for <span><sup>1</sup>H</span> and <span><sup>31</sup>P MRI</span>/<span>MRS</span> integrated with <span>NIRS</span> data acquisition Open
Purpose Our aim was to design and build a 3T 31 P/ 1 H calf coil that is capable of providing both good 31 P and 1 H transmit and receive performance, as well as being capable of accommodating a near‐infrared spectroscopy (NIRS) device for…
View article: Correlated MR spectroscopic imaging of breast cancer to investigate metabolites and lipids: acceleration and compressed sensing reconstruction
Correlated MR spectroscopic imaging of breast cancer to investigate metabolites and lipids: acceleration and compressed sensing reconstruction Open
Objectives: The main objective of this work was to detect novel biomarkers in breast cancer by spreading the MR spectra over two dimensions in multiple spatial locations using an accelerated 5D EP-COSI technology. Methods: The 5D EP-COSI d…
View article: Dictionary learning compressed sensing reconstruction: pilot validation of accelerated echo planar J-resolved spectroscopic imaging in prostate cancer
Dictionary learning compressed sensing reconstruction: pilot validation of accelerated echo planar J-resolved spectroscopic imaging in prostate cancer Open
Objectives This study aimed at developing dictionary learning (DL) based compressed sensing (CS) reconstruction for randomly undersampled five-dimensional (5D) MR Spectroscopic Imaging (3D spatial + 2D spectral) data acquired in prostate c…
View article: White matter of perinatally HIV infected older youths shows low frequency fluctuations that may reflect glial cycling
White matter of perinatally HIV infected older youths shows low frequency fluctuations that may reflect glial cycling Open
In perinatally HIV-infected (PHIV) children, neurodevelopment occurs in the presence of HIV-infection, and even with combination antiretroviral therapy (cART) the brain can be a reservoir for latent HIV. Consequently, patients often demons…
View article: Noninvasive assessment of abdominal adipose tissues and quantification of hepatic and pancreatic fat fractions in type 2 diabetes mellitus
Noninvasive assessment of abdominal adipose tissues and quantification of hepatic and pancreatic fat fractions in type 2 diabetes mellitus Open
View article: White matter microstructure among perinatally HIV-infected youth: a diffusion tensor imaging study
White matter microstructure among perinatally HIV-infected youth: a diffusion tensor imaging study Open
View article: Assessment of Lipid and Metabolite Changes in Obese Calf Muscle Using Multi-Echo Echo-planar Correlated Spectroscopic Imaging
Assessment of Lipid and Metabolite Changes in Obese Calf Muscle Using Multi-Echo Echo-planar Correlated Spectroscopic Imaging Open
View article: A comparative study between infectious and systemic inflammation
A comparative study between infectious and systemic inflammation Open
Activation of innate immune system may occur as a result of either external (mostly infection-mediated inflammation) or internal factors (systemic inflammation). Distinct stimuli act on the immune cells to induce diverse pathways leading t…
View article: Obstructive sleep apnea is associated with altered midbrain chemical concentrations
Obstructive sleep apnea is associated with altered midbrain chemical concentrations Open
View article: Echo-Planar J-resolved Spectroscopic Imaging using Dual Read-outs: Implementation and Quantitation of Human Brain Metabolites
Echo-Planar J-resolved Spectroscopic Imaging using Dual Read-outs: Implementation and Quantitation of Human Brain Metabolites Open
View article: Improvements in brain and behavior following eradication of hepatitis C
Improvements in brain and behavior following eradication of hepatitis C Open
View article: Accelerated Echo Planer J-resolved Spectroscopic Imaging of Putamen and Thalamus in Obstructive Sleep Apnea
Accelerated Echo Planer J-resolved Spectroscopic Imaging of Putamen and Thalamus in Obstructive Sleep Apnea Open
View article: Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women
Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women Open
Hyperandrogenism in normal weight PCOS women is associated with preferential intra-abdominal fat deposition and an increased population of small SC abdominal adipocytes that could constrain SC adipose storage and promote metabolic dysfunct…
View article: Obstructive sleep apnea is associated with low <scp>GABA</scp> and high glutamate in the insular cortex
Obstructive sleep apnea is associated with low <span>GABA</span> and high glutamate in the insular cortex Open
Summary The insular cortex is injured in obstructive sleep apnea ( OSA ) and responds inappropriately to autonomic challenges, suggesting neural reorganization. The objective of this study was to assess whether the neural changes might res…
View article: Accelerated echo planar <i>J</i>‐resolved spectroscopic imaging in prostate cancer: a pilot validation of non‐linear reconstruction using total variation and maximum entropy
Accelerated echo planar <i>J</i>‐resolved spectroscopic imaging in prostate cancer: a pilot validation of non‐linear reconstruction using total variation and maximum entropy Open
The overlap of metabolites is a major limitation in one‐dimensional (1D) spectral‐based single‐voxel MRS and multivoxel‐based MRSI. By combining echo planar spectroscopic imaging (EPSI) with a two‐dimensional (2D) J ‐resolved spectroscopic…
View article: Comparison Clustering using Cosine and Fuzzy set based Similarity Measures of Text Documents
Comparison Clustering using Cosine and Fuzzy set based Similarity Measures of Text Documents Open
Keeping in consideration the high demand for clustering, this paper focuses on understanding and implementing K-means clustering using two different similarity measures. We have tried to cluster the documents using two different measures r…
View article: Neuroimaging abnormalities, neurocognitive function, and fatigue in patients with hepatitis C
Neuroimaging abnormalities, neurocognitive function, and fatigue in patients with hepatitis C Open
Our results suggest that HCV-associated neurologic complications disrupt frontostriatal structures, which may result in increased fatigue and poorer cognitive performance, particularly in those cognitive domains regulated by frontostriatal…