Manoj Murhekar
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View article: Acute encephalitis syndrome and Japanese encephalitis in India: insights from a nationally representative laboratory surveillance network, 2014–2023
Acute encephalitis syndrome and Japanese encephalitis in India: insights from a nationally representative laboratory surveillance network, 2014–2023 Open
The VRDLN has substantially enhanced India's capacity to diagnose and monitor AES and JE. Despite progress, JE transmission persists, particularly in endemic regions, posing significant public health challenges. Strengthened surveillance, …
View article: Risk of Swine Influenza Virus Spillover at the Human-Swine Interface – a Scoping Review
Risk of Swine Influenza Virus Spillover at the Human-Swine Interface – a Scoping Review Open
Objectives We conducted this scoping review to describe the factors that influence the risk of spillover of Swine Influenza Virus (SIV) at various human-swine interfaces. Methods We used the PubMed and EMBASE databases to identify relevant…
View article: Epidemiology of Human Metapneumovirus (HMPV) in India: a cross-sectional study
Epidemiology of Human Metapneumovirus (HMPV) in India: a cross-sectional study Open
View article: Methodological issue in a dental neuromelioidosis outbreak investigation—authors’ reply
Methodological issue in a dental neuromelioidosis outbreak investigation—authors’ reply Open
View article: Surveillance of severe acute respiratory infections (SARI) and influenza-like illness (ILI) in Tamil Nadu, India: a situation analysis
Surveillance of severe acute respiratory infections (SARI) and influenza-like illness (ILI) in Tamil Nadu, India: a situation analysis Open
Background Evidence from the COVID-19 pandemic illustrates the substantial burden Influenza-like illness (ILI) and Severe acute respiratory infections (SARI) exert on our health system and community. While there are no large-scale studies …
View article: Availability of anti-rabies vaccine and rabies immunoglobulin in Indian health facilities: a nationwide cross-sectional health facility survey
Availability of anti-rabies vaccine and rabies immunoglobulin in Indian health facilities: a nationwide cross-sectional health facility survey Open
Indian Council of Medical Research.
View article: Neuromelioidosis outbreak in Tamil Nadu, India: an investigation of transmission with genomic insights
Neuromelioidosis outbreak in Tamil Nadu, India: an investigation of transmission with genomic insights Open
View article: Protocol for nationwide surveillance of Acute Encephalitis Syndrome (AES) in a network of tertiary care hospitals in India
Protocol for nationwide surveillance of Acute Encephalitis Syndrome (AES) in a network of tertiary care hospitals in India Open
View article: Correction: Hyperglycemia and steroid use increase the risk of rhino-orbito-cerebral mucormycosis regardless of COVID-19 hospitalization: Case-control study, India
Correction: Hyperglycemia and steroid use increase the risk of rhino-orbito-cerebral mucormycosis regardless of COVID-19 hospitalization: Case-control study, India Open
[This corrects the article DOI: 10.1371/journal.pone.0272042.].
View article: Seropositivity of Chikungunya in an outbreak setting, India: A systematic review and meta-analysis
Seropositivity of Chikungunya in an outbreak setting, India: A systematic review and meta-analysis Open
A BSTRACT Context: Since 2005, the chikungunya virus (CHIKV) has caused numerous outbreaks in India. Though it causes many outbreaks every year, the disease dynamics are poorly understood in an outbreak setting. Aims: Hence, we conducted t…
View article: Adverse drug reactions in persons initiated on treatment for drug-resistant tuberculosis in Kerala, India: A non-concurrent cohort study
Adverse drug reactions in persons initiated on treatment for drug-resistant tuberculosis in Kerala, India: A non-concurrent cohort study Open
View article: Piloting an event-based surveillance model in private hospitals for early detection of disease clusters, Kerala, India
Piloting an event-based surveillance model in private hospitals for early detection of disease clusters, Kerala, India Open
Background & objectives Event-based surveillance (EBS) is a critical component of early warning systems for detecting and responding to infectious disease outbreaks. While EBS is widely used in public health settings, its integration into …
View article: Prediction of mortality and prioritisation to tertiary care using the ‘OUR-ARCad’ risk score gleaned from the second wave of COVID-19 pandemic—A retrospective cohort study from South India
Prediction of mortality and prioritisation to tertiary care using the ‘OUR-ARCad’ risk score gleaned from the second wave of COVID-19 pandemic—A retrospective cohort study from South India Open
Background Judicious utilisation of tertiary care facilities through appropriate risk stratification assumes priority, in a raging pandemic, of the nature of delta variant-predominated second wave of COVID-19 pandemic in India. Prioritisat…
View article: Implications for influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces
Implications for influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces Open
Background and objectives The Southeast Asian Region (SEAR) faces a heightened risk of reassortment of circulating influenza viruses in swine populations due to the dense cohabitation of humans, poultry and swine. However, there is current…
View article: Hospital-Based Surveillance of Respiratory Viruses Among Children Under Five Years of Age with ARI and SARI in Eastern UP, India
Hospital-Based Surveillance of Respiratory Viruses Among Children Under Five Years of Age with ARI and SARI in Eastern UP, India Open
Acute respiratory infections (ARIs) are a leading cause of death in children under five globally. The seasonal trends and profiles of respiratory viruses vary by region and season. Due to limited information and the population’s vulnerabil…
View article: Evaluation of the Drug-Resistant Tuberculosis (DR-TB) management component under the National Tuberculosis Elimination Program (NTEP) in Kerala, India, 2021-22
Evaluation of the Drug-Resistant Tuberculosis (DR-TB) management component under the National Tuberculosis Elimination Program (NTEP) in Kerala, India, 2021-22 Open
Background and Objective: We evaluated the DR-TB component of the National Tuberculosis Elimination Program (NTEP) in a high-burden district in Kerala to identify the programmatic gaps, if any, in screening, diagnosis, treatment, and follo…
View article: Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India
Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India Open
View article: Drone-based medical delivery in the extreme conditions of Himalayan region: a feasibility study
Drone-based medical delivery in the extreme conditions of Himalayan region: a feasibility study Open
Introduction Unmanned aerial vehicles, or drones, have emerged as versatile tools across various sectors, including defence, agriculture, surveillance, mining, infrastructure, emergency response, transportation, geospatial mapping and nota…
View article: Bridging the “know-do” gap to improve active case finding for tuberculosis in India: A qualitative exploration into national tuberculosis elimination program staffs’ perspectives
Bridging the “know-do” gap to improve active case finding for tuberculosis in India: A qualitative exploration into national tuberculosis elimination program staffs’ perspectives Open
Background In 2022, India’s national tuberculosis (TB) elimination program (NTEP) commissioned a national level evaluation of active case finding (ACF) for TB to guide evidence-based strategic planning. As part of this evaluation, based on…
View article: Factors associated with delayed health-seeking behaviour and disease severity on admission among patients diagnosed with acute encephalitis syndrome: an observational study from North India
Factors associated with delayed health-seeking behaviour and disease severity on admission among patients diagnosed with acute encephalitis syndrome: an observational study from North India Open
Introduction Acute encephalitis syndrome (AES) poses a significant health challenge to children across India. Late arrival at tertiary care hospitals is a primary contributor to disease severity and poor outcomes. This study identifies the…
View article: An Outbreak of Acute Hemorrhagic Conjunctivitis Caused by Coxsackievirus A24 in Eastern Uttar Pradesh, India 2023
An Outbreak of Acute Hemorrhagic Conjunctivitis Caused by Coxsackievirus A24 in Eastern Uttar Pradesh, India 2023 Open
Introduction: Acute hemorrhagic conjunctivitis (AHC) outbreaks are caused mostly by viruses. During July-August 2023, there was a sudden spike in acute hemorrhage conjunctivitis cases in Eastern Uttar Pradesh, India. To identify the etiolo…
View article: Seropositivity of chikungunya in hospital setting, India: A systematic review and meta-analysis
Seropositivity of chikungunya in hospital setting, India: A systematic review and meta-analysis Open
Backround: Information about the chikungunya disease burden by age groups and geographic distribution is necessary to guide appropriate control measures. With this, we conducted a systematic review and meta-analysis to estimate the disease…
View article: Analysis of Cholera Risk in India: Insights from 2017–18 Serosurvey Data Integrated with Epidemiologic data and Societal Determinants from 2015–2019
Analysis of Cholera Risk in India: Insights from 2017–18 Serosurvey Data Integrated with Epidemiologic data and Societal Determinants from 2015–2019 Open
Background Indian subcontinent being an important region in the fight to eliminate cholera needs better cholera surveillance. Current methods miss most infections, skewing disease burden estimates. Triangulating serosurvey data, clinical c…
View article: Human metapneumovirus (hMPV): an associated etiology of severe acute respiratory infection in children of Eastern Uttar Pradesh, India
Human metapneumovirus (hMPV): an associated etiology of severe acute respiratory infection in children of Eastern Uttar Pradesh, India Open
Acute respiratory infections (ARIs) are a serious public health concern across the world, causing considerable morbidity and mortality. Every year, around 13 million children under the age of five die. Approximately 95% of them are from de…
View article: Human Metapneumovirus (hMPV): An associated etiology of Severe Acute Respiratory Infection in Children of Eastern Uttar Pradesh, India.
Human Metapneumovirus (hMPV): An associated etiology of Severe Acute Respiratory Infection in Children of Eastern Uttar Pradesh, India. Open
Acute respiratory infections (ARIs) are a serious public health concern across the world, causing considerable morbidity and mortality. Every year, around 13 million children under the age of five die. Approximately 95% of them are from de…
View article: <i>Ni-kshay Poshan Yojana</i> : receipt and utilization among persons with TB notified under the National TB Elimination Program in India, 2022
<i>Ni-kshay Poshan Yojana</i> : receipt and utilization among persons with TB notified under the National TB Elimination Program in India, 2022 Open
Majority of the PwTB received atleast one NPY instalment, but they experience significant delays. Most of the recipients utilised NPY for nutrition. Longitudinal follow-up studies are required to study the impact of NPY on treatment outcom…
View article: Lessons Learned From a Peer-Supported Differentiated Care and Nutritional Supplementation for People With TB in a Southern Indian State
Lessons Learned From a Peer-Supported Differentiated Care and Nutritional Supplementation for People With TB in a Southern Indian State Open
Two critical components of patient support systems for people with TB are regular counseling and locally managed nutritional support. As part of an ongoing differentiated TB care initiative called Tamil Nadu Kasanoi Erappila Thittam (meani…
View article: Human Metapneumovirus (hMPV): An associated etiology of Severe Acute Respiratory Infection in Children of Eastern Uttar Pradesh, India.
Human Metapneumovirus (hMPV): An associated etiology of Severe Acute Respiratory Infection in Children of Eastern Uttar Pradesh, India. Open
Acute respiratory infections (ARIs) are a serious public health concern across the world, causing considerable morbidity and mortality. Every year, around 13 million children under the age of five die. Approximately 95% of them are from de…
View article: Validation of the Scrub Typhus Encephalitis Assessment Tool for the Management of Acute Encephalitis Syndrome
Validation of the Scrub Typhus Encephalitis Assessment Tool for the Management of Acute Encephalitis Syndrome Open
Introduction: Acute encephalitis syndrome (AES) is one of the important causes of mortality among children in India. Active management of the cases, followed by addressing the cause of AES, is the key strategy for preventing mortality. Lac…
View article: Association between COVID-19 Vaccination (ChAdOx1-S) and Thromboembolic, Thrombocytopenic, Hemorrhagic Events: A Systematic Review and Meta-analysis of Analytical Epidemiological Studies
Association between COVID-19 Vaccination (ChAdOx1-S) and Thromboembolic, Thrombocytopenic, Hemorrhagic Events: A Systematic Review and Meta-analysis of Analytical Epidemiological Studies Open
We conducted a systematic review of analytical epidemiological studies to assess the association between ChAdOx1-S vaccination and thromboembolic, thrombocytopenic, and hemorrhagic events. We searched Medline, Embase, Google Scholar, WHO-C…