Manolis Tzatzarakis
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View article: Assessment of cat exposure to phthalates through phthalate metabolites analysis in the hair samples
Assessment of cat exposure to phthalates through phthalate metabolites analysis in the hair samples Open
View article: Blood Melatonin in Breast Milk-Fed Preterm Infants: Longitudinal Biomonitoring to 38 Weeks’ Postmenstrual Age (ProMote Study)
Blood Melatonin in Breast Milk-Fed Preterm Infants: Longitudinal Biomonitoring to 38 Weeks’ Postmenstrual Age (ProMote Study) Open
Background/Objectives: Melatonin, produced by the placenta and pineal gland, regulates circadian timing and has antioxidant and immunomodulatory actions. After birth, neonatal secretion is low and its circadian pattern matures over months;…
View article: Insights into the Prognostic Value of Telomere Length in Childhood Acute Lymphoblastic Leukemia
Insights into the Prognostic Value of Telomere Length in Childhood Acute Lymphoblastic Leukemia Open
Background: Although telomere length maintenance is a common characteristic of hematological malignancies, the role of telomere length as a prognostic factor to stratify acute lymphoblastic leukemia (ALL) patients depending on their risk o…
View article: Maternal Lifestyle During Pregnancy and Its Influence on Offspring’s Telomere Length
Maternal Lifestyle During Pregnancy and Its Influence on Offspring’s Telomere Length Open
Telomeres are protective DNA sequences located at chromosome ends, essential to maintaining genomic stability. This narrative review examines how maternal lifestyle factors during pregnancy influence fetal telomere length (TL). Positive as…
View article: Correlation of telomere length between full and preterm neonates and their mothers
Correlation of telomere length between full and preterm neonates and their mothers Open
Telomeres are nucleoprotein complexes that serve as protective caps from the DNA damage response at the ends of chromosomes. During aging, telomeres gradually shorten, and genomic instability arises through the induction of senescence. The…
View article: The Telomere Length Signature in Leukemias—From Molecular Mechanisms Underlying Telomere Shortening to Immunotherapeutic Options Against Telomerase
The Telomere Length Signature in Leukemias—From Molecular Mechanisms Underlying Telomere Shortening to Immunotherapeutic Options Against Telomerase Open
The nucleoprotein structures known as telomeres provide genomic integrity by protecting the ends of chromosomes. Tumorigenesis is associated with alterations in telomere function and stability. This narrative review provides evidence of th…
View article: The Interplay Between Obesity and Type 2 Diabetes: Common Pathophysiological Mechanisms Contributing to Telomere Shortening
The Interplay Between Obesity and Type 2 Diabetes: Common Pathophysiological Mechanisms Contributing to Telomere Shortening Open
The worldwide prevalence of obesity continues to increase, representing a serious public health issue due to associated comorbidities. Obesity is associated with type 2 diabetes mellitus (T2D), which shares similar pathophysiological mecha…
View article: The impact of exercise on telomere length dynamics: Molecular mechanisms and implications in athletes (Review)
The impact of exercise on telomere length dynamics: Molecular mechanisms and implications in athletes (Review) Open
View article: Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis
Assessment of Bisphenol A (BPA) Exposure in Dairy Cows Using Hair Samples Analysis Open
Bisphenol A (BPA) is a plasticizer known to have various adverse effects on humans and animals. Exposure of farm animals to BPA negatively impacts their health and poses a threat to humans who consume products of animal origin. Despite the…
View article: The development of preterm infants from low socio-economic status families: The combined effects of melatonin, autonomic nervous system maturation and psychosocial factors (ProMote): A study protocol
The development of preterm infants from low socio-economic status families: The combined effects of melatonin, autonomic nervous system maturation and psychosocial factors (ProMote): A study protocol Open
Preterm births constitute a major public health issue and a chronic, cross-generational condition globally. Psychological and biological factors interact in a way that women from low socio-economic status (SES) are disproportionally affect…
View article: Occurrence of 3-Monochloropropane-1,2-diol (3-MCPD) in edible oil, soy sauce and infant formula: A systematic review
Occurrence of 3-Monochloropropane-1,2-diol (3-MCPD) in edible oil, soy sauce and infant formula: A systematic review Open
View article: Author Correction: Concentration levels of phthalate metabolites in wild boar hair samples
Author Correction: Concentration levels of phthalate metabolites in wild boar hair samples Open
View article: Quercetin Intake and Absolute Telomere Length in Patients with Type 2 Diabetes Mellitus: Novel Findings from a Randomized Controlled Before-and-After Study
Quercetin Intake and Absolute Telomere Length in Patients with Type 2 Diabetes Mellitus: Novel Findings from a Randomized Controlled Before-and-After Study Open
Telomeres, the protective chromosomal ends, progressively shorten and potentially are implicated in the pathogenesis of age-related diseases. In type 2 diabetes (T2DM), telomere shortening may play an important role, but the whole ‘picture…
View article: The Impact of the Mediterranean Diet on Telomere Biology: Implications for Disease Management—A Narrative Review
The Impact of the Mediterranean Diet on Telomere Biology: Implications for Disease Management—A Narrative Review Open
Introduction: Telomeres are nucleoprotein complexes at the ends of chromosomes that are under the control of genetic and environmental triggers. Accelerated telomere shortening is causally implicated in the increasing incidence of diseases…
View article: Concentration levels of phthalate metabolites in wild boar hair samples
Concentration levels of phthalate metabolites in wild boar hair samples Open
View article: Autonomic nervous system dysregulation in children with monosymptomatic nocturnal enuresis
Autonomic nervous system dysregulation in children with monosymptomatic nocturnal enuresis Open
Aim To investigate the role of autonomic nervous system in subpopulations of children with enuresis. Methods We included 35 children with enuresis, divided in children with (17) and without nocturnal polyuria (18) and 43 healthy controls. …
View article: Exposure assessment of dairy cows to parabens using hair samples analysis
Exposure assessment of dairy cows to parabens using hair samples analysis Open
View article: Benefits of Quercetin on Glycated Hemoglobin, Blood Pressure, PiKo-6 Readings, Night-Time Sleep, Anxiety, and Quality of Life in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial
Benefits of Quercetin on Glycated Hemoglobin, Blood Pressure, PiKo-6 Readings, Night-Time Sleep, Anxiety, and Quality of Life in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial Open
Background: Diabetes is a rapidly growing global morbidity issue with high prevalence, and the associated dysglycemia leads to complications. Patients with type 2 diabetes mellitus (T2DM) often experience elevated anxiety levels, affecting…
View article: Biomonitoring of parabens in wild boars through hair samples analysis
Biomonitoring of parabens in wild boars through hair samples analysis Open
Parabens are compounds widely utilized in the industry as preservative additives to personal care products, cosmetics and food. They pollute the environment and penetrate to the living organisms through the digestive tract, respiratory sys…
View article: Evaluating tobacco product flavors using a combination of sensory and chemical analysis
Evaluating tobacco product flavors using a combination of sensory and chemical analysis Open
reports of data from original research.• Policy Case Studies -brief articles on policy development at a regional or national level.• Study Protocols -Articles describing a research protocol of a study.• Methodology Papers -Papers that pres…
View article: Telomere length as a predictive biomarker in osteoporosis (Review)
Telomere length as a predictive biomarker in osteoporosis (Review) Open
Telomeres are the ends of chromosomes that protect them from DNA damage. There is evidence to suggest that telomere shortening appears with advanced age. Since aging is a significant risk factor for developing age-related complications, it…
View article: DNA Damage Estimation after Chronic and Combined Exposure to Endocrine Disruptors: An In Vivo Real-Life Risk Simulation Approach
DNA Damage Estimation after Chronic and Combined Exposure to Endocrine Disruptors: An In Vivo Real-Life Risk Simulation Approach Open
Exposure to chemical substances has always been a matter of concern for the scientific community. During the last few years, researchers have been focusing on studying the effects resulting from combined exposure to different substances. I…
View article: Role of telomere length in human carcinogenesis (Review)
Role of telomere length in human carcinogenesis (Review) Open
Cancer is considered the most important clinical, social and economic issue regarding cause‑specific disability‑adjusted life years among all human pathologies. Exogenous, endogenous and individual factors, including genetic predisposition…
View article: EUREST-RISE: European Regulatory Science on Tobacco – Research and Innovation StaffExchange
EUREST-RISE: European Regulatory Science on Tobacco – Research and Innovation StaffExchange Open
reports of data from original research.• Policy Case Studies -brief articles on policy development at a regional or national level.• Study Protocols -Articles describing a research protocol of a study.• Methodology Papers -Papers that pres…
View article: EUREST-RISE: An innovative networking and training project on European Tobacco Control
EUREST-RISE: An innovative networking and training project on European Tobacco Control Open
1. Kyriakos CN, Qi D, Chang K, Laverty AA, Filippidis FT. Global market trends of flavor capsule cigarettes and menthol (non-capsule) cigarettes: An ecological analysis using commercial data across 78 countries, 2010–2020. Tob Induc Dis. 2…
View article: Endocrine-Disrupting Chemicals and Persistent Organic Pollutants in Infant Formulas and Baby Food: Legislation and Risk Assessments
Endocrine-Disrupting Chemicals and Persistent Organic Pollutants in Infant Formulas and Baby Food: Legislation and Risk Assessments Open
Human milk is the healthiest option for newborns, although, under specific circumstances, infant formula is a precious alternative for feeding the baby. Except for the nutritional content, infant formulas and baby food must be pollutant-fr…
View article: Chemical Warfare in Ancient Greek Ionia: Mass Intoxication With Hecate’s Deleterium
Chemical Warfare in Ancient Greek Ionia: Mass Intoxication With Hecate’s Deleterium Open
The rich land of Erythrae in the coast of Asia Minor attracted the attention of the Ionian king Codrus. An oracle demanded the presence of the murky deity Hecate for him to conquer the city. Priestess Chrysame was sent by Thessalians to se…
View article: P03-22 Evaluation of surgical stress impact over immune response against SARS-CoV-2. A pilot study
P03-22 Evaluation of surgical stress impact over immune response against SARS-CoV-2. A pilot study Open
View article: Antibiotics in Raw Meat Samples: Estimation of Dietary Exposure and Risk Assessment
Antibiotics in Raw Meat Samples: Estimation of Dietary Exposure and Risk Assessment Open
The extensive use of antibiotics in livestock farming poses increased concerns for human health as residues of these substances are present in edible tissues. The aim of this study was the determination of the levels of four groups of anti…
View article: Hair Sample Analysis of Residents from Olsztyn, Northeastern Poland, to Evaluate Levels of Bisphenol S and Bisphenol A: A Pilot Study
Hair Sample Analysis of Residents from Olsztyn, Northeastern Poland, to Evaluate Levels of Bisphenol S and Bisphenol A: A Pilot Study Open
BACKGROUND Bisphenol A (BPA) and its analogue bisphenol S (BPS), widely utilized in numerous fields of industry, may seep into the environment and into human organisms. Hitherto, BPA was regarded as the bisphenol to which people were expos…