Manoranjan Sharma
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View article: A Novel Selective NLRP3 Inhibitor Shows Disease Modifying Potential in Animal Models of Parkinson's Disease
A Novel Selective NLRP3 Inhibitor Shows Disease Modifying Potential in Animal Models of Parkinson's Disease Open
View article: Absorption Kinetics of Monosaccharides, Disaccharides and its combination with its impact on glucose availability.
Absorption Kinetics of Monosaccharides, Disaccharides and its combination with its impact on glucose availability. Open
Carbohydrates are the primary macronutrients that humans consume to support the body’s need for a source of energy. Monosaccharides like glucose are the simplest form of carbohydrate that is readily absorbed in the bloodstream, followed by…
View article: Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor
Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor Open
View article: Optimisation of Momelotinib with Improved Potency and Efficacy as Pan-Jak Inhibitor
Optimisation of Momelotinib with Improved Potency and Efficacy as Pan-Jak Inhibitor Open
View article: Challenges and Outcomes of COVID-19 Positive Neurosurgical Patients: An Institutional Experience With Emphasis on Modifications of Neurosurgical Practice
Challenges and Outcomes of COVID-19 Positive Neurosurgical Patients: An Institutional Experience With Emphasis on Modifications of Neurosurgical Practice Open
View article: The Art and Science of Negotiation – An Analysis
The Art and Science of Negotiation – An Analysis Open
While the issue of negotiation has long been considered important in a variety of individual, group, societal and cross-country settings, this issue has acquired greater significance of late. This paper examines differing schools of though…
View article: ZYBT1, a potent, irreversible Bruton’s Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer
ZYBT1, a potent, irreversible Bruton’s Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer Open
Bruton's tyrosine kinase (BTK) plays a central and pivotal role in controlling the pathways involved in the pathobiology of cancer, rheumatoid arthritis (RA), and other autoimmune disorders. ZYBT1 is a potent, irreversible, specific BTK in…
View article: Dialysis dysequilibrium syndrome in a case of hemorrhagic stroke with chronic kidney disease: Bermuda triangle of neurocritical care
Dialysis dysequilibrium syndrome in a case of hemorrhagic stroke with chronic kidney disease: Bermuda triangle of neurocritical care Open
View article: Investigation into the Role of PI3K and JAK3 Kinase Inhibitors in Murine Models of Asthma
Investigation into the Role of PI3K and JAK3 Kinase Inhibitors in Murine Models of Asthma Open
Asthma is a clinical disorder commonly characterized by chronic eosinophilic inflammation, remodeling and hyper responsiveness of the airways. However, the kinases like Phosphoinositide 3 kinase (PI3K) and Janus kinase 3 (JAK3) are involve…