Mansur Ramalan
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Effect of Plant Biomass Adsorbents on the Disposition of Cyanide in Wistar Rats Exposed to Sublethal Dose of Cyanide Open
Background: Chemical intoxication of dietary origin is one of the significant public health problems confronting the global community. Cyanide is a very toxic chemical that reacts and forms a stable complex with iron in ferric cytochrome o…
Prevalence of Thyroid Dysfunction and Autoimmunity among First Degree Relatives of Patients with Graves’ Disease at Aminu Kano Teaching Hospital, Kano, Nigeria. Open
Background: Graves’ disease has a familial predisposition with about 15% of the patients having a close relative with the same disorder, while about 50% of the relatives of patients with Graves’ have circulating thyroid autoantibodies. Thi…
Sonographic Determination of Thyroid Gland Volume among Apparently Healthy School-aged Children in Northern Nigeria Open
Introduction: The establishment of normative thyroid volumes for school-aged children is pivotal for accurate assessments of thyroid health, especially in regions impacted by iodine-related interventions. This study aimed to determine the …
Sonographic Determination of Gallbladder Dimension among Apparently Healthy School-aged Children in Kano Metropolis Open
Introduction: The present study was carried out to sonographically evaluate gallbladder dimensions among healthy school-aged children, thus setting up normal ranges that can be used in clinical settings. The study aimed to establish normal…
Efficacy of a fixed-ratio combination of glucagon-like peptide-1 receptor agonist and basal insulin therapy for the treatment of type 2 diabetes: a protocol for systematic review and meta-analysis of randomized clinical trials Open
Background Blood glucose control is a major goal of management demonstrated by many guidelines and results of clinical trials. Achieving good glycaemia is associated with reduction of the risks of cardiovascular disease. Glucagon like pept…
Anticonvulsant Effect of Ethyl Acetate and n-hexane Fractions of Celosia leptostachya Leaf Extracts in Mice Open
Anticonvulsant Effect of Ethyl Acetate and n-hexane Fractions of Celosia leptostachya Leaf Extracts in Mice
Doppler sonographic characteristics and clinical outcomes of diabetic foot syndrome: A 5-year audit from a tertiary hospital in northern Nigeria Open
Background: Diabetes foot syndrome is one of the common complications of diabetes. Detailed information on the clinical and vascular characteristics of patients with diabetic foot disease in relation to the outcome of the care provided to …
Diabetes Mellitus and Its Risk Factors among A Suburban Population Of Northwestern Nigerians; A Community-Based Survey Open
Background: Diabetes mellitus is a serious public health problem, and its prevalence is increasing globally. However, there are scanty reports of the scope and burden of the disease among suburban populations of Nigeria. This study aims to…
Prevalence and risk factors of diabetes foot ulcers in Kano, northwestern Nigeria Open
Background Foot complications account for more hospital admissions than any other diabetes mellitus (DM) complications with adverse outcomes being foot ulcers and amputation. Objective To determine the prevalence and risk factors of diabet…
Amaranthus viridis improves relative anxiety behaviour and cognitive deficit in rotenone induced Parkinsonism in albino rats Open
Background: Parkinson’s disease (PD) is typically characterised by motor shortfalls. However, non-motor symptoms like mood disorders (anxiety, depression) and impaired cognition are also associated features. Previous studies have demonstra…
Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Nigeria: A Systematic Review and Meta Analysis of Seroprevalence Studies Open
Background: In early 2020, Nigeria recorded its first case of COVID-19. The disease later became a pandemic with devastating consequences on the health and population globally. The exact incidence of the disease in Nigeria has not been rep…
Sonographic Determination of Thyroid Gland Volume among Patients with Type 2 Diabetes Mellitus in Northern Nigeria Open
Background: Thyroid disease and type 2 diabetes mellitus (T2DM) are interconnected endocrine disorders with a bidirectional relationship. T2DM patients may present with various thyroid abnormalities, such as gland enlargement and nodule fo…
Extract of Celosia leptostachya Leaves Inhibits Cobra Venom Toxins Open
Background: Celosia leptostachya belongs to Amaranthaceae plant family. Its leaves are used traditionally in the treatment of conditions, such as convulsion, eye infection and most notably to cure snakebites. This study investigated the in…
Evaluation of the antiulcer and antimicrobial activities of methanol leaf extract of Helianthus annuus Open
Background: Medicinal plants are widely used in treating and preventing specific diseases and are known to play an important role in health care. Helianthus annuus is one of such plants whose therapeutic applications no doubt have numerous…
Prevalence and Risk factors of Diabetes foot ulcers in Kano, Northwestern Nigeria Open
Background: Foot complications account for more hospital admissions than any other Diabetes Mellitus (DM) complications with adverse outcomes being foot ulcers and amputation. Objective:To determine the prevalence and risk factors of diabe…
View article: Prevalence and Determinants of Endothelial Dysfunction among Adults Living with HIV in Northwest Nigeria
Prevalence and Determinants of Endothelial Dysfunction among Adults Living with HIV in Northwest Nigeria Open
HIV-positive status, lower estimated GFR, and higher LDL cholesterol levels were independently associated with endothelial dysfunction. Future prospective studies with larger cohorts of persons living with HIV (and age- and sex-matched HIV…
Prevalence and Trends of Adult Overweight and Obesity in Nigeria — A Systematic Review and Meta-Analysis Open
Background: The prevalence of obesity and its attendant complications are on the increase globally—sub-Saharan Africa inclusive. Obesity confers an increased risk of coronary artery disease, type 2 diabetes, ischemic stroke, and some cance…
The anti-seizure and anti-nociceptive potential of hexane fraction from the leaves of Detarium senegalense Open
Detarium senegalense, J.F. Gmelin (Fabaceae) is used in Nigerian folk medicine to treat different diseases including epilepsy, microbial infections, gastrointestinal diseases and inflammation; its efficacy is widely acclaimed among communi…
Challenges and Implications of the COVID-19 Pandemic on Mental Health: A Systematic Review Open
The measures put in place to contain the rapid spread of COVID-19 infection, such as quarantine, self-isolation, and lockdown, were supportive but have significantly affected the mental wellbeing of individuals. The primary goal of this st…
Health-Related Quality of Life of Persons with Diabetic Foot Ulcers in a Cosmopolitan City in Northwestern Nigeria Open
Background: Diabetic foot ulcer is one of the most serious and disabling complications of diabetes mellitus (DM). It is a major source of morbidity, mortality, and a leading cause of hospitalization. It constitutes a major burden to the pa…
Comparative effects of combinations of metformin, omega-3 and omega-6 oil in the treatment of alloxan-induced diabetic rats Open
Emerging evidence suggests beneficial effects of omega fatty acids on diabetic complications. This study was designed to investigate the impact of Omega-3 and Omega-6 oil in the management of oxidative stress associated with complications …
View article: Effects of hydromethanol hypocotyls extract of Borassus aethiopum on sperm and gonadal indices of male Wistar rats
Effects of hydromethanol hypocotyls extract of Borassus aethiopum on sperm and gonadal indices of male Wistar rats Open
Infertility resulting from sperm dysfunction is a serious health problem leading to psychological, economic, and medical implications worldwide. Borassus aethiopum is a plant that has been used as an aphrodisiac. This study evaluated the e…
Determinants of Nigerian Medical Doctors' Willingness to Practice in Foreign Countries Open
Background: Despite the poor doctor–patient ratio in Nigeria, which is far below the World Health Organization's recommendation, Nigerian doctors are known to contribute a significant proportion of the medical workforce in other countries,…
Anti-nociceptive, anti-inflammatory and antipyretic activities of the ethanol root bark extract of Salacia lehmbachii in rats and mice Open
Background: The decoction of the roots of Salacia lehmbachi is used in traditional medicine for the treatment different diseases such as malaria pains diabetes and microbial infections.Methods: Phytochemical screening and oral acute toxici…
Influences on the Incidence and Pathomorphological Picture of Thyroid Disease Open
Background: A talon cusp is an accessory cusp-like dental anomaly that projects from the cingulum or cementoenamel junction to the incisal edge of the maxillary or mandibular anterior teeth in both primary and permanent dentition.A signifi…
A scientific compendium of the effects of sildenafil citrate on the liver, kidney and heart of male albino rats at Nnewi, South East Nigeria Open
This study investigated the various effects of Sildenafil citrate on the liver, kidney and heart of male albino rats. Twenty eight male rats randomly divided into 4 groups and weighing 131-214g were used. While the animals in group 1 (cont…
A scientific compendium of the effects of sildenafil citrate on the liver, kidney and heart of male albino rats at Nnewi, South East Nigeria Open
This study investigated the various effects of Sildenafil citrate on the liver, kidney and heart of male albino rats. Twenty eight male rats randomly divided into 4 groups and weighing 131-214g were used. While the animals in group 1 (cont…
Audit of carotid doppler sonography: Spectrum of findings at a tertiary hospital in Northwestern Nigeria Open
There is a statistically significant difference between sex and age with the side of lesion, degree of stenosis, segment involved, and type of atheromatous plaque. About one-fifth of our patients had incidental thyroid lesions. Therefore, …