Javier Cabrera
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View article: Randomization in Pre‐Clinical Studies: When Evolution Theory Meets Statistics
Randomization in Pre‐Clinical Studies: When Evolution Theory Meets Statistics Open
Randomization is a statistical procedure used to allocate study subjects randomly into experimental groups while balancing continuous variables. This paper presents an alternative to random allocation for creating homogeneous groups by bal…
View article: Optimization of the Distribution Chain of the Meat Marketing Sector through Facility Location Models
Optimization of the Distribution Chain of the Meat Marketing Sector through Facility Location Models Open
Understanding marketing as a structural and functional system that manages the product at the moment it leaves the establishment until it reaches the consumer, it is necessary to have the objective of having optimal marketing places that i…
View article: A Novel Two-stage Deming Regression Framework with Applications to Association Analysis between Clinical Risks
A Novel Two-stage Deming Regression Framework with Applications to Association Analysis between Clinical Risks Open
In healthcare, clinical risks are crucial for treatment decisions, yet the analysis of their associations is often overlooked. This gap is particularly significant when balancing risks that are weighed against each other, as in the case of…
View article: US Initiative to Eliminate Racial and Ethnic Disparities in Health: The Impact on the Outcomes of ST‐Segment–Elevation Myocardial Infarction in New Jersey
US Initiative to Eliminate Racial and Ethnic Disparities in Health: The Impact on the Outcomes of ST‐Segment–Elevation Myocardial Infarction in New Jersey Open
Background In 1998, President Clinton launched a federal initiative to eliminate racial and ethnic health disparities. The impact on the outcomes of ST‐segment–elevation myocardial infarction has not been well studied. Methods and Results …
View article: Particle count estimation in dilution series experiments
Particle count estimation in dilution series experiments Open
Estimation of microorganism concentration in samples (bacterial cells or viral particles) has been a focal point in biomedical experiments for more than a century. Serial dilution of the samples is often used to estimate the target concent…
View article: Assessment of one-year risk of ischemic stroke versus major bleeding in patients with atrial fibrillation
Assessment of one-year risk of ischemic stroke versus major bleeding in patients with atrial fibrillation Open
The new model for risk assessment of ischemic stroke and major bleeding within one year of the index AF hospital admission proposed in this work used objective, empirically driven measures, and subjective assessment of the outcomes' import…
View article: A Statewide Study of Cardiovascular Outcomes in Patients with Ankylosing Spondylitis
A Statewide Study of Cardiovascular Outcomes in Patients with Ankylosing Spondylitis Open
Numerous studies have shown that ankylosing spondylitis is associated with an increased risk of cardiovascular disease including heart failure, acute myocardial infarction, stroke, transient ischemic attack, and cardiovascular mortality. T…
View article: Comparing Cumulative Trends (with an application to COVID-19 data)
Comparing Cumulative Trends (with an application to COVID-19 data) Open
Many applications involve looking at and comparing trends in data. We will discuss some statistics that could be used to assess the similarity or dissimilarity between pairs of cumulative trends. These statistics can then be used to study …
View article: Socioeconomic data predict adverse cardiovascular outcomes
Socioeconomic data predict adverse cardiovascular outcomes Open
Background/Introduction Socioeconomic status (SES) factors predict the occurrence of adverse cardiovascular (CV) outcomes. Purpose SES has been studied in many contexts. We present data on SES in a new context using yelp, an American publi…
View article: Influencing factors of Barthel index scores among the community-dwelling elderly in Hong Kong: a random intercept model
Influencing factors of Barthel index scores among the community-dwelling elderly in Hong Kong: a random intercept model Open
Background Barthel Index (BI) is one of the most widely utilized tools for assessing functional independence in activities of daily living. Most existing BI studies used populations with specific diseases (e.g., Alzheimer’s and stroke) to …
View article: Clinical and Pregnancy Outcomes of Coronavirus Disease 2019 Among Hospitalized Pregnant Women in the United States
Clinical and Pregnancy Outcomes of Coronavirus Disease 2019 Among Hospitalized Pregnant Women in the United States Open
Background Pregnant women with coronavirus disease 2019 (COVID-19) may be at greater risk of poor maternal and pregnancy outcomes. This retrospective analysis reports clinical and pregnancy outcomes among hospitalized pregnant women with C…
View article: Association of Socioeconomic Status with One-Year Readmission and Mortality among Patients with Acute Myocardial Infarction
Association of Socioeconomic Status with One-Year Readmission and Mortality among Patients with Acute Myocardial Infarction Open
Background: Mortality and morbidity are known to be negatively associated with socioeconomic status (SES). This research aims to investigate the magnitude of this association at the individual level: household income (a proxy for the SES) …
View article: Bootstrap Confidence Intervals Using the Likelihood Ratio Test in Changepoint Detection
Bootstrap Confidence Intervals Using the Likelihood Ratio Test in Changepoint Detection Open
This study aims to evaluate the performance of power in the likelihood ratio test for changepoint detection by bootstrap sampling, and proposes a hypothesis test based on bootstrapped confidence interval lengths. Assuming i.i.d normally di…
View article: A Personalized Health Monitoring System for Community-Dwelling Elderly People in Hong Kong: Design, Implementation, and Evaluation Study
A Personalized Health Monitoring System for Community-Dwelling Elderly People in Hong Kong: Design, Implementation, and Evaluation Study Open
Background Telehealth is an effective means to assist existing health care systems, particularly for the current aging society. However, most extant telehealth systems employ individual data sources by offline data processing, which may no…
View article: Readmission and mortality among heart failure patients with history of hypertension in a statewide database
Readmission and mortality among heart failure patients with history of hypertension in a statewide database Open
Objective was to examine the temporal trends in readmission and mortality of heart failure (HF) patients with history of hypertension. This study includes 51 141 patients with history of hypertension who were discharged with a first diagno…
View article: Clinical and Nonclinical Effects on Operative Duration: Evidence from a Database on Thoracic Surgery
Clinical and Nonclinical Effects on Operative Duration: Evidence from a Database on Thoracic Surgery Open
Background . Due to the high maintenance costs, it is critical to make full use of operating rooms (ORs). Operative duration is an important factor that guides research on surgery scheduling. Clinical effects, for example, surgery type, ra…
View article: SOH Estimation and SOC Recalibration of Lithium-Ion Battery with Incremental Capacity Analysis & Cubic Smoothing Spline
SOH Estimation and SOC Recalibration of Lithium-Ion Battery with Incremental Capacity Analysis & Cubic Smoothing Spline Open
Conventional state of health (SOH) estimation often requires capacity measurement from battery’s full charge or discharge profile between fully charged state and cut-off state. Incremental capacity analysis can improve estimation efficienc…
View article: Association of orthostatic hypertension with mortality in the Systolic Hypertension in the Elderly Program
Association of orthostatic hypertension with mortality in the Systolic Hypertension in the Elderly Program Open
We examined the association of orthostatic hypertension with all-cause mortality in the active treatment and placebo randomized groups of the Systolic Hypertension in the Elderly Program (SHEP). SHEP was a multicenter, randomized, double-b…
View article: Climate risk and food availability in Guatemala
Climate risk and food availability in Guatemala Open
In this paper, we use a computable general equilibrium model to simulate the effects of drought and a decrease in agricultural productivity caused by climate change in Guatemala. A reduction in agricultural productivity would mean a consid…
View article: Abstract Mining.
Abstract Mining. Open
We have developed an application that will take a MEDLINE output from the PubMed database and allows the user to cluster all non-trivial words of the abstracts of the PubMed output. The number of clusters to use can be selected by the user…
View article: Abstract Mining
Abstract Mining Open
We have developed an application that will take a "MEDLINE" output from the PubMed database and allows the user to cluster all non-trivial words of the abstracts of the PubMed output. The number of clusters to use can be selected by the us…
View article: Clinical and Non-clinical Effects on Surgery Duration: Statistical Modeling and Analysis
Clinical and Non-clinical Effects on Surgery Duration: Statistical Modeling and Analysis Open
Surgery duration is usually used as an input to the operation room (OR) allocation and surgery scheduling problems. A good estimation of surgery duration benefits the operation planning in ORs. In contrast, we would like to investigate whe…
View article: Predicting Surgery Duration from a New Perspective: Evaluation from a Database on Thoracic Surgery
Predicting Surgery Duration from a New Perspective: Evaluation from a Database on Thoracic Surgery Open
BACKGROUND: Clinical factors influence surgery duration. This study also investigated non-clinical effects. METHODS: 22 months of data about thoracic operations in a large hospital in China were reviewed. Linear and nonlinear regression mo…