Manuel Eichenlaub
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View article: Performance of a New Continuous Glucose Monitoring System in German Adults Living with Diabetes
Performance of a New Continuous Glucose Monitoring System in German Adults Living with Diabetes Open
The study was registered under ClinicalTrials.gov (ID: NCT05806554).
View article: Clinical assessment and acceptance criteria for continuous glucose monitoring (CGM) system performance: A proposed guideline by the IFCC Working Group on CGM
Clinical assessment and acceptance criteria for continuous glucose monitoring (CGM) system performance: A proposed guideline by the IFCC Working Group on CGM Open
Continuous glucose monitoring (CGM) systems are essential tools for modern diabetes care. However, the assessment of their analytical performance has been hindered by a lack of standardization. This poses challenges for the field, as the c…
View article: Discrepancies between current displayed and auto‐logged glucose values in <scp>FreeStyle</scp> Libre 3: Implications for clinical interpretation
Discrepancies between current displayed and auto‐logged glucose values in <span>FreeStyle</span> Libre 3: Implications for clinical interpretation Open
Aims The FreeStyle Libre 3 (FSL3) continuous glucose monitoring (CGM) system provides both auto‐logged glucose values (AL) and current displayed glucose values (CUR). These values are often assumed to be interchangeable; however, discrepan…
View article: Comparative Performance Analysis of Manual and Updated Optional Calibration Algorithms for the CareSens Air CGM System
Comparative Performance Analysis of Manual and Updated Optional Calibration Algorithms for the CareSens Air CGM System Open
Background: The CE-marked CareSens Air continuous glucose monitoring (CGM) system (CSAir) features a 15-day sensor lifetime, a 2-hour warm-up period and mandatory manual calibrations. During subsequent product development, the algorithm wa…
View article: Recommendations on the Collection of Comparator Measurement Data in the Performance Evaluation of Continuous Glucose Monitoring Systems
Recommendations on the Collection of Comparator Measurement Data in the Performance Evaluation of Continuous Glucose Monitoring Systems Open
While current systems for continuous glucose monitoring (CGM) are safe and effective, there is a high degree of variability between readings within and across CGM systems. In current CGM performance studies, device readings are compared wi…
View article: A comparative analysis of glycemic metrics derived from three continuous glucose monitoring (CGM) systems
A comparative analysis of glycemic metrics derived from three continuous glucose monitoring (CGM) systems Open
ObjectiveThis study analyzed the differences in continuous glucose monitoring (CGM)-derived metrics between three current-generation systems and evaluated their impact on therapeutic decision-making. Research Design and Methods23 participa…
View article: A comparative analysis of glycemic metrics derived from three continuous glucose monitoring (CGM) systems
A comparative analysis of glycemic metrics derived from three continuous glucose monitoring (CGM) systems Open
ObjectiveThis study analyzed the differences in continuous glucose monitoring (CGM)-derived metrics between three current-generation systems and evaluated their impact on therapeutic decision-making. Research Design and Methods23 participa…
View article: A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitoring Systems
A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitoring Systems Open
OBJECTIVE This study analyzed the differences in continuous glucose monitoring (CGM)-derived metrics among three current-generation systems and evaluated their impact on therapeutic decision-making. RESEARCH DESIGN AND METHODS Twenty-three…
View article: Feasibility of a Glucose Manipulation Procedure for the Standardized Performance Evaluation of Continuous Glucose Monitoring Systems
Feasibility of a Glucose Manipulation Procedure for the Standardized Performance Evaluation of Continuous Glucose Monitoring Systems Open
Background: In continuous glucose monitoring (CGM) system performance studies, it is common to implement specific procedures for manipulating the participants’ blood glucose (BG) levels during the collection of comparator BG measurements. …
View article: Performance of Three Continuous Glucose Monitoring Systems in Adults With Type 1 Diabetes
Performance of Three Continuous Glucose Monitoring Systems in Adults With Type 1 Diabetes Open
Background: The performance of continuous glucose monitoring (CGM) systems is difficult to compare due to different study designs and a lack of head-to-head studies. This study evaluated the performance of FreeStyle Libre 3 (FL3), Dexcom G…
View article: The Need for Standardization of Continuous Glucose Monitoring Performance Evaluation: An Opinion by the International Federation of Clinical Chemistry and Laboratory Medicine Working Group on Continuous Glucose Monitoring
The Need for Standardization of Continuous Glucose Monitoring Performance Evaluation: An Opinion by the International Federation of Clinical Chemistry and Laboratory Medicine Working Group on Continuous Glucose Monitoring Open
Metrics derived from continuous glucose monitoring (CGM) systems are often discordant between systems. A major cause is that CGM systems are not standardized; they use various algorithms and calibration methods, leading to discordant CGM r…
View article: Characteristics of Nocturnal Hypoglycaemic Events and Their Impact on Glycaemia
Characteristics of Nocturnal Hypoglycaemic Events and Their Impact on Glycaemia Open
Background: Nocturnal hypoglycaemia is a burden for people with diabetes, particularly when treated with multiple daily injections (MDI) therapy. However, the characteristics of nocturnal hypoglycaemic events in this patient group are only…
View article: Performance of a Novel Continuous Glucose Monitoring Device in People With Diabetes
Performance of a Novel Continuous Glucose Monitoring Device in People With Diabetes Open
Background: In this multicenter study, performance of a novel continuous glucose monitoring (CGM) system was evaluated. Methods: Adult participants with diabetes were included in the study. They each wore three sensors of the CGM system on…
View article: A Proposal for the Clinical Characterization of Continuous Glucose Monitoring Trend Arrow Accuracy
A Proposal for the Clinical Characterization of Continuous Glucose Monitoring Trend Arrow Accuracy Open
The assessment and characterization of trend accuracy, that is, the ability of a continuous glucose monitoring (CGM) system to correctly indicate the direction and rate of change (RoC) of glucose levels, has received comparatively little a…
View article: Comparator Data Characteristics and Testing Procedures for the Clinical Performance Evaluation of Continuous Glucose Monitoring Systems
Comparator Data Characteristics and Testing Procedures for the Clinical Performance Evaluation of Continuous Glucose Monitoring Systems Open
Comparing the performance of different continuous glucose monitoring (CGM) systems is challenging due to the lack of comprehensive guidelines for clinical study design. In particular, the absence of concise requirements for the distributio…
View article: Clinical Performance Evaluation of Continuous Glucose Monitoring Systems: A Scoping Review and Recommendations for Reporting
Clinical Performance Evaluation of Continuous Glucose Monitoring Systems: A Scoping Review and Recommendations for Reporting Open
The use of different approaches for design and results presentation of studies for the clinical performance evaluation of continuous glucose monitoring (CGM) systems has long been recognized as a major challenge in comparing their results.…
View article: Comment on Hochfellner et al. Accuracy Assessment of the GlucoMen® Day CGM System in Individuals with Type 1 Diabetes: A Pilot Study. Biosensors 2022, 12, 106
Comment on Hochfellner et al. Accuracy Assessment of the GlucoMen® Day CGM System in Individuals with Type 1 Diabetes: A Pilot Study. Biosensors 2022, 12, 106 Open
In their recent article entitled “Accuracy Assessment of the GlucoMen® Day CGM System in Individuals with Type 1 Diabetes: A Pilot Study” [...]
View article: Performance Assessment of Three Continuous Glucose Monitoring Systems in Adults With Type 1 Diabetes
Performance Assessment of Three Continuous Glucose Monitoring Systems in Adults With Type 1 Diabetes Open
Background: FIND, the global alliance for diagnostics, identified the nonmarket-approved continuous glucose monitoring (CGM) system, FiberSense system (FBS), as a potential device for use in low- and middle-income countries. Together with …
View article: Continuous Glucose Deviation Interval and Variability Analysis (CG-DIVA): A Novel Approach for the Statistical Accuracy Assessment of Continuous Glucose Monitoring Systems
Continuous Glucose Deviation Interval and Variability Analysis (CG-DIVA): A Novel Approach for the Statistical Accuracy Assessment of Continuous Glucose Monitoring Systems Open
Background: The accuracy of continuous glucose monitoring (CGM) systems is crucial for the management of glucose levels in individuals with diabetes mellitus. However, the discussion of CGM accuracy is challenged by an abundance of paramet…
View article: Improving the Bias of Comparator Methods in Analytical Performance Assessments Through Recalibration
Improving the Bias of Comparator Methods in Analytical Performance Assessments Through Recalibration Open
Background: In analytical performance studies, the choice of comparator method plays an important role, as studies have shown that there exist relevant systematic differences (bias) between laboratory analyzers. The feasibility of retrospe…
View article: Patch Pumps: Periodic Insulin Delivery Patterns
Patch Pumps: Periodic Insulin Delivery Patterns Open
Recent in vitro experiments with patch pumps (PP) Omnipod (OP), Omnipod DASH (OP-D), A6 TouchCare (A6), and Accu-Chek Solo (ACS) have observed periodic fluctuations in the delivered amount of insulin during basal rate and consecutive bolus…
View article: Impact of Blood Glucose Monitoring System Accuracy on Clinical Decision Making for Diabetes Management
Impact of Blood Glucose Monitoring System Accuracy on Clinical Decision Making for Diabetes Management Open
Background: The accuracy of blood glucose monitoring systems (BGMS) is crucial for the safe and effective management of diabetes mellitus. Despite standardization of accuracy assessment procedures and requirements, various studies have sho…
View article: Comment on “Minimal and Maximal Models to Quantitate Glucose Metabolism: Tools to Measure, to Simulate and to Run in Silico Clinical Trials”
Comment on “Minimal and Maximal Models to Quantitate Glucose Metabolism: Tools to Measure, to Simulate and to Run in Silico Clinical Trials” Open
Comment on “Minimal and Maximal Models to Quantitate Glucose Metabolism: Tools to Measure, to Simulate and to Run in Silico Clinical Trials”
View article: A Glucose-Only Model to Extract Physiological Information from Postprandial Glucose Profiles in Subjects with Normal Glucose Tolerance
A Glucose-Only Model to Extract Physiological Information from Postprandial Glucose Profiles in Subjects with Normal Glucose Tolerance Open
Background: Current mathematical models of postprandial glucose metabolism in people with normal and impaired glucose tolerance rely on insulin measurements and are therefore not applicable in clinical practice. This research aims to devel…