Manuel Levy
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View article: Cortex-Wide Substrates for Body Schema and Action Awareness
Cortex-Wide Substrates for Body Schema and Action Awareness Open
The concept of the body schema originated from studies of patients with cortical lesions who were unable to localize their body parts in space or perceive passive movements (Head & Holmes, 1911). Current consensus defines the body schema a…
View article: Deep and dynamic metabolic and structural imaging in living tissues
Deep and dynamic metabolic and structural imaging in living tissues Open
Label-free imaging through two-photon autofluorescence of NAD(P)H allows for nondestructive, high-resolution visualization of cellular activities in living systems. However, its application to thick tissues has been restricted by its limit…
View article: Deep and Dynamic Metabolic and Structural Imaging in Living Tissues
Deep and Dynamic Metabolic and Structural Imaging in Living Tissues Open
Label-free imaging through two-photon autofluorescence (2PAF) of NAD(P)H allows for non-destructive and high-resolution visualization of cellular activities in living systems. However, its application to thick tissues and organoids has bee…
View article: Spectral-temporal-spatial customization via modulating multimodal nonlinear pulse propagation
Spectral-temporal-spatial customization via modulating multimodal nonlinear pulse propagation Open
Multimode fibers (MMFs) are gaining renewed interest for nonlinear effects due to their high-dimensional spatiotemporal nonlinear dynamics and scalability for high power. High-brightness MMF sources with effective control of the nonlinear …
View article: Somatosensory cortical signature of facial nociception and vibrotactile touch–induced analgesia
Somatosensory cortical signature of facial nociception and vibrotactile touch–induced analgesia Open
Pain relief by vibrotactile touch is a common human experience. Previous neurophysiological investigations of its underlying mechanism in animals focused on spinal circuits, while human studies suggested the involvement of supraspinal path…
View article: Somatosensory Cortical Signature of Facial Nociception and Vibrotactile Touch Induced Analgesia
Somatosensory Cortical Signature of Facial Nociception and Vibrotactile Touch Induced Analgesia Open
Pain relief by vibrotactile touch is a common human experience. Previous neurophysiological investigations in animals focused on spinal mechanisms while human studies suggested the involvement of supraspinal mechanisms. Here we asked wheth…
View article: An Unexpected Dependence of Cortical Depth in Shaping Neural Responsiveness and Selectivity in Mouse Visual Cortex
An Unexpected Dependence of Cortical Depth in Shaping Neural Responsiveness and Selectivity in Mouse Visual Cortex Open
Two-photon imaging studies in mouse primary visual cortex (V1) consistently report that around half of the neurons respond to oriented grating stimuli. However, in cats and primates, nearly all neurons respond to such stimuli. Here we show…
View article: Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during Ischemia
Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during Ischemia Open
Blood–brain barrier disruption (BBB) and release of toxic blood molecules into the brain contributes to neuronal injury during stroke and other cerebrovascular diseases. While pericytes are builders and custodians of the BBB in the normal …