Manuela Polydoro
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View article: Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons
Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons Open
Aggregates of hyperphosphorylated tau protein are a pathological hallmark of more than 20 distinct neurodegenerative diseases, including Alzheimer’s disease, progressive supranuclear palsy, and frontotemporal dementia. While the exact mech…