Manuela Sumyk
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View article: Binding of Tetracyclines to Acinetobacter baumannii TetR Involves Two Arginines as Specificity Determinants
Binding of Tetracyclines to Acinetobacter baumannii TetR Involves Two Arginines as Specificity Determinants Open
Acinetobacter baumannii is an important nosocomial pathogen that requires thoughtful consideration in the antibiotic prescription strategy due to its multidrug resistant phenotype. Tetracycline antibiotics have recently been re-administere…
View article: Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization
Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization Open
View article: Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level
Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level Open
Mammalian oocytes are arrested in the dictyate stage of meiotic prophase I for long periods of time, during which the high concentration of the p53 family member TAp63α sensitizes them to DNA damage-induced apoptosis. TAp63α is kept in an …
View article: Author response: Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level
Author response: Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level Open
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Mammalian oocytes are arreste…