Marc A. Brockmann
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View article: Deep Learning Denoising Algorithm for Improved Assessment of Coronary Arteries in Transcatheter Aortic Valve Implantation CT Imaging
Deep Learning Denoising Algorithm for Improved Assessment of Coronary Arteries in Transcatheter Aortic Valve Implantation CT Imaging Open
The DLD substantially improves image quality without affecting diagnostic accuracy for the evaluation of coronary arteries in patients undergoing pre-TAVI CT scans.
View article: Profiling disease experience in patients living with brain aneurysms by analyzing multimodal clinical data and quality of life measures
Profiling disease experience in patients living with brain aneurysms by analyzing multimodal clinical data and quality of life measures Open
To explore the mental and physical health (MH, PH) on individuals living with brain aneurysms and to profile their differences in disease experience. In N = 111 patients the Short Form 36 Health Survey (SF-36) was assessed via an online su…
View article: Middle Meningeal Artery Embolization for the Treatment of Chronic Subdural Hematomas—a German Nationwide Multi-center Study On 718 Embolizations
Middle Meningeal Artery Embolization for the Treatment of Chronic Subdural Hematomas—a German Nationwide Multi-center Study On 718 Embolizations Open
Background Embolization of the middle meningeal artery (EMMA) is a promising novel technique for the treatment of patients with chronic subdural hematomas (cSDH). Methods After a nationwide query in Germany, patients with cSDH, treated wit…
View article: Radiation Dose Reduction and Image Quality Improvement of UHR CT of the Neck by Novel Deep-learning Image Reconstruction
Radiation Dose Reduction and Image Quality Improvement of UHR CT of the Neck by Novel Deep-learning Image Reconstruction Open
Purpose We evaluated a dedicated dose-reduced UHR-CT for head and neck imaging, combined with a novel deep learning reconstruction algorithm to assess its impact on image quality and radiation exposure. Methods Retrospective analysis of ni…
View article: Prevalence and classification of posterior semicircular canal dehiscence in HRCTs of the petrous part of the temporal bone
Prevalence and classification of posterior semicircular canal dehiscence in HRCTs of the petrous part of the temporal bone Open
View article: Routine CT Diagnostics Cause Dose-Dependent Gene Expression Changes in Peripheral Blood Cells
Routine CT Diagnostics Cause Dose-Dependent Gene Expression Changes in Peripheral Blood Cells Open
The increasing use of computed tomography (CT) has led to a rise in cumulative radiation dose due to medical imaging, raising concerns about potential long-term adverse effects. Large-scale epidemiological studies indicate a higher tumor i…
View article: Deep Learning-Enhanced Ultra-high-resolution CT Imaging for Superior Temporal Bone Visualization
Deep Learning-Enhanced Ultra-high-resolution CT Imaging for Superior Temporal Bone Visualization Open
Vendor-specific DLR-enhanced UHR-CT significantly improves temporal bone image quality and diagnostic performance.
View article: Delirium following mechanical thrombectomy for ischemic stroke – individuals at risk, imaging biomarkers and prognosis
Delirium following mechanical thrombectomy for ischemic stroke – individuals at risk, imaging biomarkers and prognosis Open
Aim Post-stroke-delirium has been linked to worse outcome in patients with acute cerebrovascular disease; identification of individuals at risk may prevent delirium and thereby improve outcome. We investigate prognosis and factors associat…
View article: Vision Restoration through transorbital electrical stimulation in Optic Neuropathy in patients with significant optic atrophy due to primary open-angle glaucoma—a randomised, controlled, double-blind, multicentre clinical trial: the VIRON study protocol
Vision Restoration through transorbital electrical stimulation in Optic Neuropathy in patients with significant optic atrophy due to primary open-angle glaucoma—a randomised, controlled, double-blind, multicentre clinical trial: the VIRON study protocol Open
Introduction Glaucoma is one of the most common causes of blindness and affects more than 70 million people worldwide. The disease is characterised by the loss of retinal ganglion cells associated with a progressive optic neuropathy, resul…
View article: Retrospective multicenter analysis of the Trenza Embolization Device for endovascular therapy of intracranial aneurysms: initial results and short-term follow-up
Retrospective multicenter analysis of the Trenza Embolization Device for endovascular therapy of intracranial aneurysms: initial results and short-term follow-up Open
Background Intrasaccular devices are increasingly used in endovascular therapy of intracranial aneurysms, in particular wide-necked and ruptured aneurysms. The Trenza Embolization Device (TED) is an innovative intrasaccular device for medi…
View article: Development of a novel ovine in-vitro model of osteoporotic vertebral compression fractures (OF2) to simulate surgical interventions
Development of a novel ovine in-vitro model of osteoporotic vertebral compression fractures (OF2) to simulate surgical interventions Open
View article: Impact of extent of resection in relation to MGMT status on survival in recurrent glioblastoma
Impact of extent of resection in relation to MGMT status on survival in recurrent glioblastoma Open
View article: DSA-based perfusion parameters versus TICI score after mechanical thrombectomy in acute ischaemic stroke patients: a congruence analysis
DSA-based perfusion parameters versus TICI score after mechanical thrombectomy in acute ischaemic stroke patients: a congruence analysis Open
Background Several factors are frequently considered for outcome prediction rin stroke patients. We assessed the value of digital subtraction angiography (DSA)-based brain perfusion measurements after mechanical thrombectomy (MT) for outco…
View article: Multimodal treatment of glioblastoma with multiple lesions - a multi-center retrospective analysis
Multimodal treatment of glioblastoma with multiple lesions - a multi-center retrospective analysis Open
Objective The presence of multiple localizations (ML) in glioblastoma is rare and associated with perceived poor prognosis. The aim of this study is to evaluate the impact of a multimodal treatment on progression-free survival (PFS) and ov…
View article: Federated Voxel Scene Graph for Intracranial Hemorrhage
Federated Voxel Scene Graph for Intracranial Hemorrhage Open
Intracranial Hemorrhage is a potentially lethal condition whose manifestation is vastly diverse and shifts across clinical centers worldwide. Deep-learning-based solutions are starting to model complex relations between brain structures, b…
View article: Impact of deep Learning-enhanced contrast on diagnostic accuracy in stroke CT angiography
Impact of deep Learning-enhanced contrast on diagnostic accuracy in stroke CT angiography Open
Deep learning-augmented contrast enhancement improves the image quality and increases the sensitivity of detection vessel occlusions in poorly contrasted CTA.
View article: Deep learning-based detection and classification of intracranial tumors on magnetic resonance imaging
Deep learning-based detection and classification of intracranial tumors on magnetic resonance imaging Open
Background We evaluated the capability of an AI application to independently detect, segment and classify intracranial tumors in MRI. Methods In this retrospective single-centre study, 138 patients (65 female and 73 male) with a mean age o…
View article: Preoperative prediction of CNS WHO grade and tumour aggressiveness in intracranial meningioma based on radiomics and structured semantics
Preoperative prediction of CNS WHO grade and tumour aggressiveness in intracranial meningioma based on radiomics and structured semantics Open
View article: Detection of Intracranial Hemorrhage for Trauma Patients
Detection of Intracranial Hemorrhage for Trauma Patients Open
Whole-body CT is used for multi-trauma patients in the search of any and all injuries. Since an initial assessment needs to be rapid and the search for lesions is done for the whole body, very little time can be allocated for the inspectio…
View article: Evaluating local open-source large language models for data extraction from unstructured reports on mechanical thrombectomy in patients with ischemic stroke
Evaluating local open-source large language models for data extraction from unstructured reports on mechanical thrombectomy in patients with ischemic stroke Open
Background A study was undertaken to assess the effectiveness of open-source large language models (LLMs) in extracting clinical data from unstructured mechanical thrombectomy reports in patients with ischemic stroke caused by a vessel occ…
View article: Comparison of T1‐weighted landmark placement and ROI transfer onto diffusion‐weighted EPI sequences for targeted tractography tasks in the optic nerve
Comparison of T1‐weighted landmark placement and ROI transfer onto diffusion‐weighted EPI sequences for targeted tractography tasks in the optic nerve Open
Diffusion‐based tractography in the optic nerve requires sampling strategies assisted by anatomical landmark information (regions of interest [ROIs]). We aimed to investigate the feasibility of expert‐placed, high‐resolution T1‐weighted RO…
View article: Voxel Scene Graph for Intracranial Hemorrhage
Voxel Scene Graph for Intracranial Hemorrhage Open
Patients with Intracranial Hemorrhage (ICH) face a potentially life-threatening condition, and patient-centered individualized treatment remains challenging due to possible clinical complications. Deep-Learning-based methods can efficientl…
View article: Comparison of T1-weighted landmark placement and ROI transfer onto diffusion-weighted EPI sequences for targeted tractography tasks in the optic nerve
Comparison of T1-weighted landmark placement and ROI transfer onto diffusion-weighted EPI sequences for targeted tractography tasks in the optic nerve Open
Diffusion-based tractography in the optic nerve requires sampling strategies assisted by anatomical landmark information (regions of interest, ROIs). We aimed to investigate the feasibility of expert-placed, high resolution T1-weighted ROI…
View article: Value of vendor-agnostic deep learning image denoising in brain computed tomography: A multi-scanner study
Value of vendor-agnostic deep learning image denoising in brain computed tomography: A multi-scanner study Open
To evaluate the effect of a vendor-agnostic deep learning denoising (DLD) algorithm on diagnostic image quality of non-contrast cranial computed tomography (ncCT) across five CT scanners. This retrospective single-center study included ncC…
View article: A 3D-Printed Dummy for Training Distal Phalanx Amputation in Mice
A 3D-Printed Dummy for Training Distal Phalanx Amputation in Mice Open
The development of realistic dummies for training the distal phalanx amputation (DPA) technique in mouse pups is a promising alternative to reduce and replace animals in training for research and teaching. To test this, we obtained micro-C…
View article: Deep Learning Accelerated Brain Diffusion-Weighted MRI with Super Resolution Processing
Deep Learning Accelerated Brain Diffusion-Weighted MRI with Super Resolution Processing Open
Ultra-fast diffusion-weighted imaging with super resolution is feasible, resulting in highly accelerated brain imaging while increasing diagnostic image quality.
View article: Sex-specific Impact of the first COVID-19 Lockdown on Age Structure and Case Acuity at Admission in a Patient Population in southwestern Germany: a retrospective comparative Study in Neuroradiology
Sex-specific Impact of the first COVID-19 Lockdown on Age Structure and Case Acuity at Admission in a Patient Population in southwestern Germany: a retrospective comparative Study in Neuroradiology Open
Objectives A hard lockdown was presumed to lead to delayed diagnosis and treatment of serious diseases, resulting in higher acuity at admission. This should be elaborated based on the estimated acuity of the cases, changes in findings duri…
View article: Treatment outcome of IDH1/2 wildtype CNS WHO grade 4 glioma histologically diagnosed as WHO grade II or III astrocytomas
Treatment outcome of IDH1/2 wildtype CNS WHO grade 4 glioma histologically diagnosed as WHO grade II or III astrocytomas Open
View article: Comparing a common clavicle maturation-based age estimation method to ordinary regression analyses with quadratic and sex-specific interaction terms in adolescents
Comparing a common clavicle maturation-based age estimation method to ordinary regression analyses with quadratic and sex-specific interaction terms in adolescents Open
View article: Brain connectivity networks underlying resting heart rate variability in acute ischemic stroke
Brain connectivity networks underlying resting heart rate variability in acute ischemic stroke Open