Marc A. Maier
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View article: Divided attention and manual visuomotor control in stroke: a combined dual-task and eye movement study
Divided attention and manual visuomotor control in stroke: a combined dual-task and eye movement study Open
View article: Longitudinal brain ageing after stroke: a marker for neurodegeneration and its relevance for upper limb motor outcome
Longitudinal brain ageing after stroke: a marker for neurodegeneration and its relevance for upper limb motor outcome Open
Brain age, as distinct from chronological age, may reveal post-stroke recovery mechanisms, but longitudinal studies tracking brain age are lacking. We explored longitudinal change of brain age post-stroke and its relation to upper limb sen…
View article: Increased dual-task interference during upper limb movements in stroke exceeding that found in aging – a systematic review and meta-analysis
Increased dual-task interference during upper limb movements in stroke exceeding that found in aging – a systematic review and meta-analysis Open
Objective To determine whether dual-task interference during upper limb tasks is increased in patients after stroke compared to healthy older subjects and to compare magnitude of stroke-induced change in interference to that explained by a…
View article: Alterations of tactile and anatomical spatial representations of the hand after stroke
Alterations of tactile and anatomical spatial representations of the hand after stroke Open
Stroke often causes long-term motor and somatosensory impairments. Motor planning and tactile perception rely on spatial body representations. However, the link between altered spatial body representations, motor deficit and tactile spatia…
View article: Post-Stroke Impairments of Manual Dexterity and Finger Proprioception: Their Contribution to Upper Limb Activity Capacity
Post-Stroke Impairments of Manual Dexterity and Finger Proprioception: Their Contribution to Upper Limb Activity Capacity Open
Background Knowing how impaired manual dexterity and finger proprioception affect upper limb activity capacity is important for delineating targeted post-stroke interventions for upper limb recovery. Objectives To investigate whether impai…
View article: Efficacy of interactive manual dexterity training after stroke: a pilot single-blinded randomized controlled trial
Efficacy of interactive manual dexterity training after stroke: a pilot single-blinded randomized controlled trial Open
Objective To compare the efficacy of Dextrain Manipulandum™ training of dexterity components such as force control and independent finger movements, to dose-matched conventional therapy (CT) post-stroke. Methods A prospective, single-blind…
View article: The Resume Paradox: Greater Language Differences, Smaller Pay Gaps
The Resume Paradox: Greater Language Differences, Smaller Pay Gaps Open
Over the past decade, the gender pay gap has remained steady with women earning 84 cents for every dollar earned by men on average. Many studies explain this gap through demand-side bias in the labor market represented through employers' j…
View article: A tablet-based quantitative assessment of manual dexterity for detection of early psychosis
A tablet-based quantitative assessment of manual dexterity for detection of early psychosis Open
Background We performed a pilot study on whether tablet-based measures of manual dexterity can provide behavioral markers for detection of first-episode psychosis (FEP), and whether cortical excitability/inhibition was altered in FEP. Meth…
View article: Motor inhibition and its contribution to recovery of dexterous hand use after stroke
Motor inhibition and its contribution to recovery of dexterous hand use after stroke Open
Recovery of dexterous hand use is critical for functional outcome after stroke. Grip force recordings can inform on maximal motor output and modulatory and inhibitory cerebral functions, but how these actually contribute to recovery of dex…
View article: A novel tablet-based application for assessment of manual dexterity and its components: a reliability and validity study in healthy subjects
A novel tablet-based application for assessment of manual dexterity and its components: a reliability and validity study in healthy subjects Open
Background We developed five tablet-based tasks (applications) to measure multiple components of manual dexterity. Aim: to test reliability and validity of tablet-based dexterity measures in healthy participants. Methods Tasks included: (1…
View article: Multisensory Integration in Stroke Patients: A Theoretical Approach to Reinterpret Upper-Limb Proprioceptive Deficits and Visual Compensation
Multisensory Integration in Stroke Patients: A Theoretical Approach to Reinterpret Upper-Limb Proprioceptive Deficits and Visual Compensation Open
For reaching and grasping, as well as for manipulating objects, optimal hand motor control arises from the integration of multiple sources of sensory information, such as proprioception and vision. For this reason, proprioceptive deficits …
View article: Interpretable bias mitigation for textual data: Reducing gender bias in\n patient notes while maintaining classification performance
Interpretable bias mitigation for textual data: Reducing gender bias in\n patient notes while maintaining classification performance Open
Medical systems in general, and patient treatment decisions and outcomes in\nparticular, are affected by bias based on gender and other demographic\nelements. As language models are increasingly applied to medicine, there is a\ngrowing int…
View article: Neural noise and cortical inhibition in schizophrenia
Neural noise and cortical inhibition in schizophrenia Open
View article: Common vs. Distinct Visuomotor Control Deficits in Autism Spectrum Disorder and Schizophrenia
Common vs. Distinct Visuomotor Control Deficits in Autism Spectrum Disorder and Schizophrenia Open
Autism spectrum disorder (ASD) and schizophrenia (SCZ) are neurodevelopmental disorders with partly overlapping clinical phenotypes including sensorimotor impairments. However, direct comparative studies on sensorimotor control across thes…
View article: Locomotor kinematics and EMG activity during quadrupedal versus bipedal gait in the Japanese macaque
Locomotor kinematics and EMG activity during quadrupedal versus bipedal gait in the Japanese macaque Open
Several qualitative features distinguish bipedal from quadrupedal locomotion in mammals. In this study we show quantitative differences between quadrupedal and bipedal gait in the Japanese monkey in terms of gait patterns, trunk/hindlimb k…
View article: Impaired attentional modulation of sensorimotor control and cortical excitability in schizophrenia
Impaired attentional modulation of sensorimotor control and cortical excitability in schizophrenia Open
Impairments in attentional, working memory and sensorimotor processing have been consistently reported in schizophrenia. However, the interaction between cognitive and sensorimotor impairments and the underlying neural mechanisms remains l…
View article: Higurashi et al_R1_SupplementalTable_S1.docx
Higurashi et al_R1_SupplementalTable_S1.docx Open
Higurashi et al_R1_SupplementalTable_S1.docx
View article: Higurashi et al_R1_SupplementalTable_S2.docx
Higurashi et al_R1_SupplementalTable_S2.docx Open
Higurashi et al_R1_SupplementalTable_S2.docx
View article: Supplemental Table S1
Supplemental Table S1 Open
Supplemental Table S1 (J Neurophysiol) 20190322
View article: Predictive Modulation of Corticospinal Excitability and Implicit Encoding of Movement Probability in Schizophrenia
Predictive Modulation of Corticospinal Excitability and Implicit Encoding of Movement Probability in Schizophrenia Open
The ability to infer from uncertain information is impaired in schizophrenia and is associated with hallucinations and false beliefs. The accumulation of information is a key process for generating a predictive internal model, which statis…
View article: Individual recovery profiles of manual dexterity, and relation to corticospinal lesion load and excitability after stroke –a longitudinal pilot study
Individual recovery profiles of manual dexterity, and relation to corticospinal lesion load and excitability after stroke –a longitudinal pilot study Open
View article: Manual Dexterity and Aging: A Pilot Study Disentangling Sensorimotor From Cognitive Decline
Manual Dexterity and Aging: A Pilot Study Disentangling Sensorimotor From Cognitive Decline Open
Manual dexterity measures can be useful for early detection of age-related functional decline and for prediction of cognitive decline. However, what aspects of sensorimotor function to assess remains unclear. Manual dexterity markers shoul…
View article: Axonal myelin decrease in the splenium in major depressive disorder
Axonal myelin decrease in the splenium in major depressive disorder Open
The corpus callosum has become a key area of interest for researchers in severe mental illness. Disruptions in fractional anisotropy in the callosum have been reported in schizophrenia and major depressive disorder. No change has been repo…
View article: Cerebello-Cortical Differences in Effective Connectivity of the Dominant and Non-dominant Hand during a Visuomotor Paradigm of Grip Force Control
Cerebello-Cortical Differences in Effective Connectivity of the Dominant and Non-dominant Hand during a Visuomotor Paradigm of Grip Force Control Open
Structural and functional differences are known to exist within the cortical sensorimotor networks with respect to the dominant vs. non-dominant hand. Similarly, the cerebellum, a key structure in the sensorimotor network with its cerebell…
View article: Manual Dexterity in Schizophrenia—A Neglected Clinical Marker?
Manual Dexterity in Schizophrenia—A Neglected Clinical Marker? Open
Impaired manual dexterity is commonly observed in schizophrenia. However, a quantitative description of key sensorimotor components contributing to impaired dexterity is lacking. Whether the key components of dexterity are differentially a…
View article: Does dystonic muscle activity affect sense of effort in cervical dystonia?
Does dystonic muscle activity affect sense of effort in cervical dystonia? Open
This study shows that muscle afferent feedback biases sense of effort cues when controlling neck forces in patients with CD. The bias acts on peripheral or central sense of effort cues depending on whether the task involves dystonic muscle…
View article: Kinetic DTI of the cervical spine: diffusivity changes in healthy subjects
Kinetic DTI of the cervical spine: diffusivity changes in healthy subjects Open
View article: Kinetic DTI of the cervical spine: diffusivity changes in healthy subjects
Kinetic DTI of the cervical spine: diffusivity changes in healthy subjects Open
View article: Upper Limb Outcome Measures Used in Stroke Rehabilitation Studies: A Systematic Literature Review
Upper Limb Outcome Measures Used in Stroke Rehabilitation Studies: A Systematic Literature Review Open
The results showed a large diversity of outcome measures used across studies. However, a growing number of studies used the FMT, a neurological test with good psychometric properties. For thorough assessment the FMT needs to be combined wi…
View article: A novel method for the quantification of key components of manual dexterity after stroke
A novel method for the quantification of key components of manual dexterity after stroke Open