Marc Buse
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View article: Newer B-cell and plasma-cell targeted treatments for rituximab-resistant patients with membranous nephropathy
Newer B-cell and plasma-cell targeted treatments for rituximab-resistant patients with membranous nephropathy Open
Membranous nephropathy is the most common cause of nephrotic syndrome in adults. While spontaneous remission occurs in approximately one-third of cases, another one-third of patients receiving immunosuppressive therapy demonstrate treatmen…
View article: Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species
Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species Open
Background Glucocorticoids are the treatment of choice for proteinuric patients with minimal change disease (MCD) and primary focal segmental glomerulosclerosis (FSGS). Immunosuppressive as well as direct effects on podocytes are believed …
View article: What We Have Learned so far From Single Cell Sequencing in Acute Kidney Injury
What We Have Learned so far From Single Cell Sequencing in Acute Kidney Injury Open
Acute Kidney injury is a major clinical problem associated with increased morbidity and mortality. Despite, intensive research the clinical outcome remains poor and apart from supportive therapy no other specific therapy exists. Single cel…