Marc E. Bouillon
YOU?
Author Swipe
View article: Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica
Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica Open
Infection with Fasciola hepatica (liver fluke) causes fasciolosis (or fascioliasis) and poses a considerable economic as well as welfare burden to both the agricultural and animal health sectors. Here, we explore the ex vivo anthelmintic p…
View article: Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.
Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica. Open
View article: Synthesis of Anemoclemosides A and B, Two Saponins Isolated from <i>Anemoclema glaucifolium</i>
Synthesis of Anemoclemosides A and B, Two Saponins Isolated from <i>Anemoclema glaucifolium</i> Open
Steroidal and triterpenoid saponins are attractive for their wide‐ranging pharmacological properties. The triterpenoid saponins Anemoclemoside A and B are root constituents of the Chinese folk medicinal plant Anemoclema glaucifolium (Ranun…
View article: An investigation of the antileishmanial properties of semi-synthetic saponins
An investigation of the antileishmanial properties of semi-synthetic saponins Open
Hit anti-leishmanial saponin structures selected following primary and secondary screening.
View article: Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure
Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure Open
The antiprotozoal effect of saponins is transitory, as when saponins are deglycosylated to sapogenins by rumen microorganisms they become inactive. We hypothesised that the combination of saponins with glycosidase-inhibiting iminosugars mi…
View article: Antiprotozoal Effect of Saponins in the Rumen Can Be Enhanced by Chemical Modifications in Their Structure
Antiprotozoal Effect of Saponins in the Rumen Can Be Enhanced by Chemical Modifications in Their Structure Open
The antiprotozoal effect of saponins is transitory, as when saponins are deglycosylated to the sapogenin by rumen microorganisms they become inactive. We postulated that the substitution of the sugar moiety of the saponin with small polar …