Marc Garnier
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View article: Personalized driving pressure-guided positive end-expiratory pressure in patients at risk of postoperative respiratory failure (IMPROVE-2): a multicenter, pragmatic, randomized clinical trial
Personalized driving pressure-guided positive end-expiratory pressure in patients at risk of postoperative respiratory failure (IMPROVE-2): a multicenter, pragmatic, randomized clinical trial Open
View article: Compliance with antimicrobial stewardship guidelines in surgery: an observational, multidisciplinary, cohort study
Compliance with antimicrobial stewardship guidelines in surgery: an observational, multidisciplinary, cohort study Open
View article: Impact of tracheal extubation location after surgical procedures on peri‐operative times: a prospective dual‐centre observational study*
Impact of tracheal extubation location after surgical procedures on peri‐operative times: a prospective dual‐centre observational study* Open
Summary Introduction Extubation of the trachea in the operating theatre may increase the time spent there. Conversely, tracheal extubation in the post‐anaesthesia care unit may prolong the duration of anaesthesia and increase the incidence…
View article: National expert consensus on the management of antibiotic prophylaxis in surgical patients with a penicillin allergy label based on the Delphi method
National expert consensus on the management of antibiotic prophylaxis in surgical patients with a penicillin allergy label based on the Delphi method Open
Background Patients with a penicillin allergy label have an increased risk of surgical site infection. Although a decision tree was published in 2019 to define which patients could benefit from direct cephalosporin use in the perioperative…
View article: Multicentre, double-blind, randomised controlled clinical trial comparing intermittent cefoxitin administration versus loading bolus followed by continuous infusion for the prevention of surgical site infection in colorectal surgery: the PROPHYLOXITIN study protocol
Multicentre, double-blind, randomised controlled clinical trial comparing intermittent cefoxitin administration versus loading bolus followed by continuous infusion for the prevention of surgical site infection in colorectal surgery: the PROPHYLOXITIN study protocol Open
Introduction Surgical site infections (SSIs) are the second leading cause of healthcare-associated infections in Europe with the highest rates being reported in colorectal surgery (ranging from 9% to 30%). Surgical antibiotic prophylaxis (…
View article: Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis
Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis Open
View article: Effects of sevoflurane on lung alveolar epithelial wound healing and survival in a sterile in vitro model of acute respiratory distress syndrome
Effects of sevoflurane on lung alveolar epithelial wound healing and survival in a sterile in vitro model of acute respiratory distress syndrome Open
Acute respiratory distress syndrome (ARDS) is a serious lung condition that often leads to hospitalization in intensive care units and a high mortality rate. Sevoflurane is a volatile anesthetic with growing interest for sedation in ventil…
View article: SPLF/SMFU/SRLF/SFAR/SFCTCV Guidelines for the management of patients with primary spontaneous pneumothorax
SPLF/SMFU/SRLF/SFAR/SFCTCV Guidelines for the management of patients with primary spontaneous pneumothorax Open
View article: β-Lactam Pharmacokinetic/Pharmacodynamic Target Attainment in Intensive Care Unit Patients: A Prospective, Observational, Cohort Study
β-Lactam Pharmacokinetic/Pharmacodynamic Target Attainment in Intensive Care Unit Patients: A Prospective, Observational, Cohort Study Open
Background: The aims of this study were to describe pharmacokinetic/pharmacodynamic target attainment in intensive care unit (ICU) patients treated with continuously infused ß-lactam antibiotics, their associated covariates, and the impact…
View article: SPLF/SMFU/SRLF/SFAR/SFCTCV Guidelines for the management of patients with primary spontaneous pneumothorax
SPLF/SMFU/SRLF/SFAR/SFCTCV Guidelines for the management of patients with primary spontaneous pneumothorax Open
View article: Diabetes mellitus is associated with 90-day mortality in old critically ill COVID-19 patients: a multicenter prospective observational cohort study
Diabetes mellitus is associated with 90-day mortality in old critically ill COVID-19 patients: a multicenter prospective observational cohort study Open
View article: Association of preoperative COVID-19 and postoperative respiratory morbidity during the Omicron epidemic wave: the DROMIS-22 multicentre prospective observational cohort study
Association of preoperative COVID-19 and postoperative respiratory morbidity during the Omicron epidemic wave: the DROMIS-22 multicentre prospective observational cohort study Open
The study was fully funded by the French Society of Anaesthesiology and Intensive Care Medicine (SFAR).
View article: Updated meta-analysis on intraoperative inspired fraction of oxygen and the risk of surgical site infection in adults undergoing general and regional anesthesia
Updated meta-analysis on intraoperative inspired fraction of oxygen and the risk of surgical site infection in adults undergoing general and regional anesthesia Open
This updated meta-analysis aims at exploring whether the use of systematic high vs low intraoperative oxygen fraction (FiO 2 ) may decrease the incidence of postoperative surgical site infection during general (GA) or regional anesthesia (…
View article: Five-Hour Detection of Intestinal Colonization with Extended-Spectrum-β-Lactamase-Producing <i>Enterobacteriaceae</i> Using the β-Lacta Phenotypic Test: the BLESSED Study
Five-Hour Detection of Intestinal Colonization with Extended-Spectrum-β-Lactamase-Producing <i>Enterobacteriaceae</i> Using the β-Lacta Phenotypic Test: the BLESSED Study Open
To both improve the efficiency of contact isolation among ESBL-PE carriers and avoid the unnecessary isolation of noncolonized patients, we should reduce the turnaround time of ESBL screening in laboratories and improve the sensitivity of …
View article: Anaesthetic and peri-operative management for thrombectomy procedures in stroke patients
Anaesthetic and peri-operative management for thrombectomy procedures in stroke patients Open
Strong agreement among experts was reached to provide a sizable number of recommendations aimed at optimising anaesthetic management for thrombectomy in patients suffering from stroke.
View article: The association of prior paracetamol intake with outcome of very old intensive care patients with COVID-19: results from an international prospective multicentre trial
The association of prior paracetamol intake with outcome of very old intensive care patients with COVID-19: results from an international prospective multicentre trial Open
View article: Epidemiology, risk factors and prognosis of ventilator-associated pneumonia during severe COVID-19: Multicenter observational study across 149 European Intensive Care Units
Epidemiology, risk factors and prognosis of ventilator-associated pneumonia during severe COVID-19: Multicenter observational study across 149 European Intensive Care Units Open
View article: COVID-19 acute respiratory distress syndrome promotes a specific alternative macrophage polarization
COVID-19 acute respiratory distress syndrome promotes a specific alternative macrophage polarization Open
View article: Pancréatite aiguë grave du patient adulte en soins critiques 2021
Pancréatite aiguë grave du patient adulte en soins critiques 2021 Open
View article: Noninvasive ventilation in COVID-19 patients aged ≥ 70 years—a prospective multicentre cohort study
Noninvasive ventilation in COVID-19 patients aged ≥ 70 years—a prospective multicentre cohort study Open
View article: Guidelines for the management of patients with severe acute pancreatitis, 2021
Guidelines for the management of patients with severe acute pancreatitis, 2021 Open
View article: Guidelines for clothing in the operating theatre, 2021
Guidelines for clothing in the operating theatre, 2021 Open
Based on strong agreement between experts, we produced 13 recommendations to guide the choice of operating theatre attire.
View article: Design and Rationale of the Sevoflurane for Sedation in Acute Respiratory Distress Syndrome (SESAR) Randomized Controlled Trial
Design and Rationale of the Sevoflurane for Sedation in Acute Respiratory Distress Syndrome (SESAR) Randomized Controlled Trial Open
Preclinical studies have shown that volatile anesthetics may have beneficial effects on injured lungs, and pilot clinical data support improved arterial oxygenation, attenuated inflammation, and decreased lung epithelial injury in patients…
View article: Heat moisture exchange/high-efficiency particulate filters and the risk of contamination of the ventilatory circuit and patient environment with SARS-CoV-2: A brief report
Heat moisture exchange/high-efficiency particulate filters and the risk of contamination of the ventilatory circuit and patient environment with SARS-CoV-2: A brief report Open
View article: Epidural analgesia information sessions provided by anesthetic nurses: impact on satisfaction and anxiety of parturient women a prospective sequential study
Epidural analgesia information sessions provided by anesthetic nurses: impact on satisfaction and anxiety of parturient women a prospective sequential study Open
Background Information on epidural analgesia delivered to parturient women is frequently incomplete, making it difficult for expectant mothers to make an appropriate choice for their delivery. We assessed the impact of a multimodal informa…
View article: Correction to: Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19
Correction to: Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19 Open
View article: The association of the Activities of Daily Living and the outcome of old intensive care patients suffering from COVID-19
The association of the Activities of Daily Living and the outcome of old intensive care patients suffering from COVID-19 Open
View article: Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19
Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19 Open
View article: Delayed inflammation decrease is associated with mortality in Tocilizumab-treated critically ill SARS-CoV-2 patients: A retrospective matched-cohort analysis
Delayed inflammation decrease is associated with mortality in Tocilizumab-treated critically ill SARS-CoV-2 patients: A retrospective matched-cohort analysis Open
Little is known about the immuno-inflammatory response to Tocilizumab and its association with outcome in critically-ill SARS-CoV2 pneumonia. In this multicenter retrospective cohort of SARS-CoV-2 patients admitted to three intensive care …
View article: Health-related quality of life in older patients surviving ICU treatment for COVID-19: results from an international observational study of patients older than 70 years
Health-related quality of life in older patients surviving ICU treatment for COVID-19: results from an international observational study of patients older than 70 years Open
Background health-related quality of life (HRQoL) is an important patient-centred outcome in patients surviving ICU admission for COVID-19. It is currently not clear which domains of the HRQoL are most affected. Objective to quantify HRQoL…