Marc Hazzan
YOU?
Author Swipe
View article: Cell wall arabinogalactan is responsible for Fungitell® cross reactivity in nocardiosis
Cell wall arabinogalactan is responsible for Fungitell® cross reactivity in nocardiosis Open
Nocardiosis is a serious infection in immunosuppressed patients, especially transplant recipients. The slow-growing phenotype of the bacterium and the variety of symptoms complicate diagnosis and delay antimicrobial therapy, resulting in h…
View article: ECOSBot: a multicenter validation pilot study of a generative AI tool for OSCE-based nephrology training
ECOSBot: a multicenter validation pilot study of a generative AI tool for OSCE-based nephrology training Open
Background Developing diagnostic reasoning in nephrology is particularly challenging due to its pathophysiological complexity and reliance on abstract clinical data. Objective Structured Clinical Examinations (OSCEs) are pivotal for nephro…
View article: Renal Cell Carcinoma in Native Kidney After Kidney Transplantation: A Multicenter Case Control Study With a Focus on Screening Strategy
Renal Cell Carcinoma in Native Kidney After Kidney Transplantation: A Multicenter Case Control Study With a Focus on Screening Strategy Open
Renal cell carcinoma (RCC) of native kidney is more prevalent after kidney transplantation than in the general population. Risk factors and the value of screening remain unclear. We conducted a multicenter case-control study in kidney tran…
View article: Motivational factors influencing the choice of oncology as a specialty among French medical students
Motivational factors influencing the choice of oncology as a specialty among French medical students Open
Experience during hospital rotations plays a crucial role in the specialty choices made by medical students. The motivations behind choosing oncology as a specialty differ according to gender. Intrinsic motivations (interests in fundamenta…
View article: Evaluating script concordance tests (SCTs) through the lens of Bayesian reasoning: Enhancing assessment in medical education
Evaluating script concordance tests (SCTs) through the lens of Bayesian reasoning: Enhancing assessment in medical education Open
Currently, many of these questions remain unanswered in the literature, with recent data suggesting that experienced physicians' responses to SCTs are often biased. Beyond their use as an assessment tool in the EDN, SCTs offer a valuable o…
View article: Engaging Undergraduate Medical Students with Introductory Research Training via an Educational Escape Room: A Mixed-Methods Evaluation of Engagement and Perception (Preprint)
Engaging Undergraduate Medical Students with Introductory Research Training via an Educational Escape Room: A Mixed-Methods Evaluation of Engagement and Perception (Preprint) Open
International audience
View article: Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes
Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes Open
Type 2 diabetes (T2D) is a common comorbidity in kidney transplant recipients, representing a significant proportion of the candidate pool. Post-kidney transplantation management of T2D remains challenging, leading to inferior long-term ou…
View article: Cell wall arabinogalactan is responsible for Fungitell® cross reactivity in nocardiosis
Cell wall arabinogalactan is responsible for Fungitell® cross reactivity in nocardiosis Open
Nocardiosis is a serious infection in immunosuppressed patients, especially transplant recipients. The slow-growing phenotype of the bacterium and the variety of symptoms complicate diagnosis and delay antimicrobial therapy, which results …
View article: Le panel d’experts pour les tests de concordance de script : une référence réellement adéquate ?
Le panel d’experts pour les tests de concordance de script : une référence réellement adéquate ? Open
View article: Efficacy and safety of direct oral anticoagulants versus vitamin K antagonists in patients on chronic dialysis
Efficacy and safety of direct oral anticoagulants versus vitamin K antagonists in patients on chronic dialysis Open
Background Clinical trials of direct oral anticoagulants (DOAC) are scarce and inconclusive in patients who are receiving dialysis, for whom DOAC are not labelled in Europe. In a French nationwide registry study of patients on chronic dial…
View article: Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes
Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes Open
Type 2 diabetes (T2D) is a common comorbidity in kidney transplant recipients, representing a significant proportion of the candidate pool. Post-kidney transplantation management of T2D remains challenging, leading to inferior long-term ou…
View article: Kidney Transplantation After Allogeneic Hematopoietic Cell Transplantation
Kidney Transplantation After Allogeneic Hematopoietic Cell Transplantation Open
View article: Primary Graft Function and 5 Year Insulin Independence After Pancreas and Islet Transplantation for Type 1 Diabetes: A Retrospective Parallel Cohort Study
Primary Graft Function and 5 Year Insulin Independence After Pancreas and Islet Transplantation for Type 1 Diabetes: A Retrospective Parallel Cohort Study Open
In islet transplantation (ITx), primary graft function (PGF) or beta cell function measured early after last infusion is closely associated with long term clinical outcomes. We investigated the association between PGF and 5 year insulin in…
View article: Impact of Preformed Donor-Specific Anti-HLA-Cw and Anti-HLA-DP Antibodies on Acute Antibody-Mediated Rejection in Kidney Transplantation
Impact of Preformed Donor-Specific Anti-HLA-Cw and Anti-HLA-DP Antibodies on Acute Antibody-Mediated Rejection in Kidney Transplantation Open
Given the risk of rejection, the presence of preformed donor specific antibodies (DSA) contraindicates transplantation in most allocation systems. However, HLA-Cw and -DP DSA escape this censorship. We performed a multicentric observationa…
View article: Transfused Red Blood Cell Characteristics and Kidney Transplant Outcomes Among Patients Receiving Early Posttransplant Transfusion
Transfused Red Blood Cell Characteristics and Kidney Transplant Outcomes Among Patients Receiving Early Posttransplant Transfusion Open
Importance Red blood cell transfusion (RBCT) is frequently required in the early post–kidney transplant period, but long-term outcomes associated with RBCT is controversial. Therefore, it may be relevant to investigate the association betw…
View article: Prognostic value of complement serum C3 level and glomerular C3 deposits in anti-glomerular basement membrane disease
Prognostic value of complement serum C3 level and glomerular C3 deposits in anti-glomerular basement membrane disease Open
Background and objectives Activation of the complement system is involved in the pathogenesis of anti-glomerular basement membrane (anti-GBM) disease. Glomerular deposits of complement 3 (C3) are often detected on kidney biopsies. The prim…
View article: #5876 ISLET TRANSPLANTATION VERSUS INSULIN ALONE IN TYPE 1 DIABETIC KIDNEY TRANSPLANT RECIPIENTS: A FRENCH NATIONWIDE STUDY ON BEHALF OF THE TREPID GROUP
#5876 ISLET TRANSPLANTATION VERSUS INSULIN ALONE IN TYPE 1 DIABETIC KIDNEY TRANSPLANT RECIPIENTS: A FRENCH NATIONWIDE STUDY ON BEHALF OF THE TREPID GROUP Open
Background and Aims Islet transplantation is associated with a benefit on glycaemic control compared to optimized insulin therapy in recent clinical trials. However, there is a lack of evidence concerning the long-term impact of islet tran…
View article: Absence of Mortality Differences Between the First and Second COVID-19 Waves in Kidney Transplant Recipients
Absence of Mortality Differences Between the First and Second COVID-19 Waves in Kidney Transplant Recipients Open
View article: Association Between Maintenance Immunosuppressive Regimens and COVID-19 Mortality in Kidney Transplant Recipients
Association Between Maintenance Immunosuppressive Regimens and COVID-19 Mortality in Kidney Transplant Recipients Open
Background. Solid organ transplant recipients are at high risk for fatal forms of coronavirus disease 2019 (COVID-19). We conducted a cohort study among kidney transplant (KT) recipients from the French Solid Organ Transplant COVID-19 Regi…
View article: The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series
The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series Open
View article: Post-Transplantation Early Blood Transfusion and Kidney Allograft Outcomes: A Single-Center Observational Study
Post-Transplantation Early Blood Transfusion and Kidney Allograft Outcomes: A Single-Center Observational Study Open
The association between blood transfusion and the occurrence of de novo HLA donor specific antibodies (DSA) after kidney transplantation remains controversial. In this single-center observational study, we examined the association between …
View article: Impact of targeted hypothermia in expanded-criteria organ donors on recipient kidney-graft function: study protocol for a multicentre randomised controlled trial (HYPOREME)
Impact of targeted hypothermia in expanded-criteria organ donors on recipient kidney-graft function: study protocol for a multicentre randomised controlled trial (HYPOREME) Open
Introduction Expanded-criteria donors (ECDs) are used to reduce the shortage of kidneys for transplantation. However, kidneys from ECDs are associated with an increased risk of delayed graft function (DGF), a risk factor for allograft loss…
View article: Changing of therapeutic trends between the 1st and 2nd wave did not reduce COVID-19 related mortality of renal transplant recipients: a national registry study
Changing of therapeutic trends between the 1st and 2nd wave did not reduce COVID-19 related mortality of renal transplant recipients: a national registry study Open
SARS-CoV-2 pandemic evolved in two consecutive waves over 2020 (for France: 1st wave from March 1 to July 31; and 2nd wave from August 1 to December 31). Improvements in the management of COVID-19 led to a reduction of mortality rates in h…
View article: Impact of Tacrolimus Daily Dose Limitation in Renal Transplant Recipients Expressing CYP3A5: A Retrospective Study
Impact of Tacrolimus Daily Dose Limitation in Renal Transplant Recipients Expressing CYP3A5: A Retrospective Study Open
The pharmacokinetic variability of tacrolimus can be partly explained by CYP3A5 activity. Our objective was to evaluate a tacrolimus sparing policy on renal graft outcome according to CYP3A5 6986A>G genetic polymorphism. This retrospective…
View article: French nationwide survey of undocumented end-stage renal disease migrant patient access to scheduled haemodialysis and kidney transplantation
French nationwide survey of undocumented end-stage renal disease migrant patient access to scheduled haemodialysis and kidney transplantation Open
International audience
View article: Association Between Deceased Donor Acute Kidney Injury Assessed Using Baseline Serum Creatinine Back-Estimation and Graft Survival: Results From the French National CRISTAL Registry
Association Between Deceased Donor Acute Kidney Injury Assessed Using Baseline Serum Creatinine Back-Estimation and Graft Survival: Results From the French National CRISTAL Registry Open
View article: Clinical Utility of Biochemical Markers for the Prediction of COVID-19−Related Mortality in Kidney Transplant Recipients
Clinical Utility of Biochemical Markers for the Prediction of COVID-19−Related Mortality in Kidney Transplant Recipients Open
View article: Successful Reuse of Kidney Graft After Early Recurrence of Primary Focal and Segmental Glomerulosclerosis
Successful Reuse of Kidney Graft After Early Recurrence of Primary Focal and Segmental Glomerulosclerosis Open
View article: Impaired renal function before kidney procurement has a deleterious impact on allograft survival in very old deceased kidney donors
Impaired renal function before kidney procurement has a deleterious impact on allograft survival in very old deceased kidney donors Open
View article: Association between acute graft pyelonephritis and kidney graft survival: A single-center observational study
Association between acute graft pyelonephritis and kidney graft survival: A single-center observational study Open
The association between acute graft pyelonephritis (AGPN) and graft failure in kidney transplant recipients (KTR) remains controversial. In this single-center observational study, we aimed to assess the incidence of AGPN as a time-dependen…