Marc Lipman
YOU?
Author Swipe
View article: A multinational Delphi consensus on TB screening of migrants in Europe
A multinational Delphi consensus on TB screening of migrants in Europe Open
The disproportionate burden of tuberculosis among migrants in the World Health Organization European Region underscores the urgent need to address the public health challenges associated with global migration. Recommendations for screening…
View article: Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England: a multicentre, test-negative, case–control study
Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England: a multicentre, test-negative, case–control study Open
View article: “SPHERE” multi-component novel psychosocial intervention for people with HIV: study protocol for a randomised controlled trial
“SPHERE” multi-component novel psychosocial intervention for people with HIV: study protocol for a randomised controlled trial Open
International Standard Randomised Controlled Trials Number (ISRCTN) Registry: ISRCTN47187932 [registered 12 July 2024].
View article: Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study
Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study Open
View article: Optimising Non-Pharmacological Interventions in People with Non-Tuberculous Mycobacterial Pulmonary Disease: A Systematic Review
Optimising Non-Pharmacological Interventions in People with Non-Tuberculous Mycobacterial Pulmonary Disease: A Systematic Review Open
Introduction Treatment of Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD) is often complex, relying on long treatment courses with multiple antibiotics, which are associated with treatment intolerance and failure. Current guideline…
View article: Management of Nontuberculous Mycobacterial Pulmonary Disease Refractory to Guideline-Based Therapy: A Systematic Review
Management of Nontuberculous Mycobacterial Pulmonary Disease Refractory to Guideline-Based Therapy: A Systematic Review Open
Introduction Managing patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) unresponsive to guideline-based therapy presents a significant clinical challenge. Limited treatment options and the complex nature of disease prog…
View article: Chronic Obstructive Pulmonary Disease in People with HIV: an Evidence-Based Review
Chronic Obstructive Pulmonary Disease in People with HIV: an Evidence-Based Review Open
HIV co-infection is a risk factor for the development of COPD. HIV enhances the deleterious effects of exposures such as tobacco smoking, as well as interacting with other drivers of COPD such as pulmonary tuberculosis, air pollution and b…
View article: Type I interferon responses contribute to immune protection against mycobacterial infection
Type I interferon responses contribute to immune protection against mycobacterial infection Open
Type I interferon responses have been considered detrimental to host protection in tuberculosis (TB). We provide novel data to challenge this paradigm, derived from transcriptional profiling of human in vivo immune responses to discover as…
View article: Type I interferon responses contribute to immune protection against mycobacterial infection
Type I interferon responses contribute to immune protection against mycobacterial infection Open
Type I interferon responses have been considered detrimental to host protection in tuberculosis (TB). We provide novel data to challenge this paradigm, derived from transcriptional profiling of human in vivo immune responses to discover as…
View article: Author response: Type I interferon responses contribute to immune protection against mycobacterial infection
Author response: Type I interferon responses contribute to immune protection against mycobacterial infection Open
View article: A decision-making model for public health authorities in circumstances of potentially high public risk
A decision-making model for public health authorities in circumstances of potentially high public risk Open
Background An expert multidisciplinary panel was commissioned by a UK Health Security Agency led incident management team (IMT) to support decision making in the case of an individual with extensively drug-resistant tuberculosis. The behav…
View article: Impact of <scp>COVID</scp>‐19 and factors associated with long <scp>COVID</scp> and <scp>COVID</scp>‐19 vaccine uptake in people with <scp>HIV</scp> in the United Kingdom: Results from Positive Voices 2022
Impact of <span>COVID</span>‐19 and factors associated with long <span>COVID</span> and <span>COVID</span>‐19 vaccine uptake in people with <span>HIV</span> in the United Kingdom: Results from Positive Voices 2022 Open
Objectives We assessed the impact of COVID‐19, and the prevalence and factors associated with a history of COVID‐19 infection, long COVID and incomplete COVID‐19 vaccine uptake among people with HIV. Methods Positive Voices 2022 is a quest…
View article: Evolution of T cell responses in the tuberculin skin test reveals generalisable Mtb-reactive T cell metaclones
Evolution of T cell responses in the tuberculin skin test reveals generalisable Mtb-reactive T cell metaclones Open
T cells contribute to immune protection and pathogenesis in tuberculosis, but measurements of polyclonal responses have failed to resolve correlates of outcome. We report the first temporal evaluation of the human in vivo clonal repertoire…
View article: Severe acute respiratory syndrome coronavirus-2 antibody prevalence in adults with HIV
Severe acute respiratory syndrome coronavirus-2 antibody prevalence in adults with HIV Open
Objectives: To measure severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antibody seroprevalence within a cohort of adults with HIV and correlate demographics with response rates to SARS CoV-2 vaccination. Design: Initial vaccin…
View article: A micro-costing of latent tuberculosis infection testing and treatment in adults in secondary care in England
A micro-costing of latent tuberculosis infection testing and treatment in adults in secondary care in England Open
Background Latent TB infection (LTBI) screening and treatment of population groups at high risk for TB is part of England’s Tuberculosis Action Plan, which has succeeded in increasing testing volumes. However, analysis of the cost-effectiv…
View article: Predictors of specialist care referrals (SCR) following emergency department review or hospital admission in adults with previous acute COVID-19: a prospective UK cohort study
Predictors of specialist care referrals (SCR) following emergency department review or hospital admission in adults with previous acute COVID-19: a prospective UK cohort study Open
View article: Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline
Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline Open
Background: On the basis of recent clinical trial data for the treatment of drug-susceptible and drug-resistant tuberculosis (TB), the American Thoracic Society, U.S. Centers for Disease Control and Prevention, European Respiratory …
View article: Comparing short‐term mortality between people with and without <scp>HIV</scp> admitted to the intensive care unit: A single‐centre matched cohort study (2000–2019)
Comparing short‐term mortality between people with and without <span>HIV</span> admitted to the intensive care unit: A single‐centre matched cohort study (2000–2019) Open
Objectives The survival rate of people with HIV admitted to intensive care units (ICUs) is approaching that of people without HIV. We conducted a matched‐cohort study of people with and without HIV admitted to ICU at a large hospital to co…
View article: Population-Level Frequency of Fluoroquinolone Resistance by Whole-Genome Sequencing Drug Predictions in <i>Mycobacterium tuberculosis</i> Complex Isolates in England From 2017 Through 2023
Population-Level Frequency of Fluoroquinolone Resistance by Whole-Genome Sequencing Drug Predictions in <i>Mycobacterium tuberculosis</i> Complex Isolates in England From 2017 Through 2023 Open
Fluoroquinolones are increasingly important for anti-tuberculosis (TB) treatment. Identifying fluoroquinolone resistance (FR) is essential. Using sequencing data from over 16 000 unselected isolates, this first English survey of FR, found …
View article: Associations between ethnicity and persistent physical and mental health symptoms experienced as part of ongoing symptomatic COVID-19
Associations between ethnicity and persistent physical and mental health symptoms experienced as part of ongoing symptomatic COVID-19 Open
Introduction Ethnicity can influence susceptibility to SARS-CoV-2 infection, hospitalisation and death. Its association with ongoing symptomatic COVID-19 is unclear. We assessed if, among a population followed up after discharge from hospi…
View article: Providing personalised care for people with tuberculosis: an evaluation of enhanced case management in a UK TB Network 2013 to 2021
Providing personalised care for people with tuberculosis: an evaluation of enhanced case management in a UK TB Network 2013 to 2021 Open
Objectives Evaluating the outcomes of enhanced case management (ECM) for patients with tuberculosis (TB) in the North Central London TB Service (NCLTBS). Design Retrospective cohort study. Setting The NCLTBS provides care for persons diagn…
View article: Drug-resistant tuberculosis treatments, the case for a phase III platform trial
Drug-resistant tuberculosis treatments, the case for a phase III platform trial Open
Most phase III trials in drug-resistant tuberculosis have either been underpowered to quantify differences in microbiological endpoints or have taken up to a decade to complete. Composite primary endpoints, dominated by differences in trea…
View article: Bedaquiline: what might the future hold?
Bedaquiline: what might the future hold? Open
View article: Type I interferon responses contribute to immune protection against mycobacterial infection
Type I interferon responses contribute to immune protection against mycobacterial infection Open
Type I interferon responses have been considered detrimental to host protection in tuberculosis (TB). We provide novel data to challenge this paradigm, derived from transcriptional profiling of human in vivo immune responses to discover as…
View article: British <scp>HIV</scp> Association guidelines on the management of opportunistic infection in people living with <scp>HIV</scp>: The clinical management of pulmonary opportunistic infections 2024
British <span>HIV</span> Association guidelines on the management of opportunistic infection in people living with <span>HIV</span>: The clinical management of pulmonary opportunistic infections 2024 Open
With improvements in the human immunodeficiency virus (HIV) testing and treatment cascade and reductions in the prevalence of advanced HIV, the incidence of 'classic' pulmonary opportunistic infections is lower, and so these infections are…
View article: Nebulised pentamidine prophylaxis of <i>pneumocystis</i> pneumonia in adults accessing HIV services at royal free hospital, London
Nebulised pentamidine prophylaxis of <i>pneumocystis</i> pneumonia in adults accessing HIV services at royal free hospital, London Open
Receipt of nebulised pentamidine in people with HIV was audited to identify if individuals were appropriately receiving nebulised pentamidine, and whether national guidelines were being followed when prophylaxis was commenced and discontin…
View article: Non-tuberculous mycobacterial pulmonary disease (NTM-PD): Epidemiology, diagnosis and multidisciplinary management
Non-tuberculous mycobacterial pulmonary disease (NTM-PD): Epidemiology, diagnosis and multidisciplinary management Open
View article: Health and illness beliefs in adults with tuberculosis infection during the COVID-19 pandemic in the UK
Health and illness beliefs in adults with tuberculosis infection during the COVID-19 pandemic in the UK Open
NIHR RID-TB Program (RP-PG-0217-20009).
View article: Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study
Development and description of a theory-driven, evidence-based, complex intervention to improve adherence to treatment for tuberculosis in the UK: the IMPACT study Open
Background Tuberculosis (TB) has a significant treatment burden for patients, requiring at least six months of anti-TB treatment (ATT) with multiple medicines. Ensuring good adherence to ATT is central to global TB strategies, including th…
View article: The 2023 UN high-level meeting on tuberculosis: renewing hope, momentum, and commitment to end tuberculosis
The 2023 UN high-level meeting on tuberculosis: renewing hope, momentum, and commitment to end tuberculosis Open
Global efforts to end tuberculosis have saved an estimated 75 million lives this century. 1 WHOWorld Health Organization global tuberculosis report 2022. World Health Organization, Geneva2022https://iris.who.int/bitstream/handle/10665/3637…