Marc Quirynen
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View article: Autologous platelet concentrates in alveolar ridge preservation: A systematic review with meta‐analyses
Autologous platelet concentrates in alveolar ridge preservation: A systematic review with meta‐analyses Open
In order to evaluate the therapeutic advantages of various autologous platelet concentrates (APC) as a single biomaterial during alveolar ridge preservation (ARP), a systematic review with meta‐analyses was conducted. PubMed, EMBASE, Web o…
View article: Ten‐Year Follow‐Up of Oral Implants in Bone With Limited Bucco‐Oral Dimensions: A Prospective Case Series
Ten‐Year Follow‐Up of Oral Implants in Bone With Limited Bucco‐Oral Dimensions: A Prospective Case Series Open
Background It has been suggested that 1–2 mm of bone width at the buccal and lingual aspect is required for a successful long‐term implant outcome. Low levels of evidence support this minimum threshold of bone width. This prospective study…
View article: Autologous platelet concentrates after third molar extraction: A systematic review
Autologous platelet concentrates after third molar extraction: A systematic review Open
Surgical removal of impacted mandibular third molars is often followed by postoperative sequelae like pain, swelling, trismus, etc. This systematic review explored the benefits of applying different autologous platelet concentrates (APCs) …
View article: L‐PRF in extra‐oral wound care
L‐PRF in extra‐oral wound care Open
Leukocyte‐ and platelet‐rich fibrin (L‐PRF), a by‐product of centrifuged autologous whole blood, contains high concentrations of platelets, leukocytes, and fibrin (the latter spontaneously creating a strong 3‐D network (a membrane)). L‐PRF…
View article: Introduction and overview on Autogenous Platelet Concentrates
Introduction and overview on Autogenous Platelet Concentrates Open
This special issue on autologous platelet concentrates (APCs) provides clinicians with an overview on the current understanding of the use of these biomaterials for soft and hard tissue regeneration. The included papers summarize scientifi…
View article: A narrative review on the use of autologous platelet concentrates during alveolar bone augmentation: Horizontal (simultaneous/staged) & vertical (simultaneous/staged)
A narrative review on the use of autologous platelet concentrates during alveolar bone augmentation: Horizontal (simultaneous/staged) & vertical (simultaneous/staged) Open
This review aimed to answer the general question of whether autologous platelet concentrates (APCs, an autologous blood‐derivative) can improve the outcome of alveolar bone augmentation. Three clinical scenarios were assessed: horizontal/v…
View article: Instructions for the use of <scp>L‐PRF</scp> in different clinical indications
Instructions for the use of <span>L‐PRF</span> in different clinical indications Open
Autologous platelet concentrates (APCs) have demonstrated clear benefits across various clinical applications, including alveolar ridge preservation, guided tissue regeneration, guided bone regeneration, sinus floor elevation (both lateral…
View article: Impact of autologous platelet concentrates on the osseointegration of dental implants
Impact of autologous platelet concentrates on the osseointegration of dental implants Open
Osseointegration is defined as the direct deposition of bone onto biomaterial devices, most commonly composed from titanium, for the purpose of anchoring dental prostheses. The use of autologous platelet concentrates (APC) has the potentia…
View article: <scp>APCs</scp> in sinus floor augmentation
<span>APCs</span> in sinus floor augmentation Open
After tooth loss in the posterior area of the maxilla, sinus floor elevation is often required to compensate the vertical bone loss due to sinus pneumatization. This narrative review reports on the potential benefits of autologous platelet…
View article: Small‐diameter titanium grade IV and titanium–zirconium implants in edentulous mandibles: Ten‐year results from a double‐blind, randomised controlled split‐mouth core‐trial
Small‐diameter titanium grade IV and titanium–zirconium implants in edentulous mandibles: Ten‐year results from a double‐blind, randomised controlled split‐mouth core‐trial Open
The goal of this extension study was to compare the 10‐year outcome of 3.3 mm diameter titanium–zirconium (TiZr) or grade IV titanium (Ti) implants in mandibular implant‐overdentures. Materials and Methods This study is the 10‐year follow‐…
View article: Non‐invasive oral implant position assessment: An ex vivo study using a <scp>3D</scp> industrial scan as the reference model to mimic the clinical situation
Non‐invasive oral implant position assessment: An ex vivo study using a <span>3D</span> industrial scan as the reference model to mimic the clinical situation Open
Aim To introduce an objective method to evaluate the accuracy of implant position assessment in partially edentulous patients by comparing different techniques (conventional impression, intraoral scan, CBCT) to a reference 3D model obtaine…
View article: Individual “alveolar phenotype” limits dimensions of lateral bone augmentation
Individual “alveolar phenotype” limits dimensions of lateral bone augmentation Open
Aim Alveolar ridge resorption following tooth extraction often renders a lateral bone augmentation inevitable. Some patients, however, suffer from severe early (during graft healing, E res ) and/or late (during follow‐up, L res ) graft res…
View article: Surgical guides for guided bone augmentation: An <i>in vitro</i> study
Surgical guides for guided bone augmentation: An <i>in vitro</i> study Open
Aim To validate in vitro the accuracy of a novel method for bone augmentation of horizontal alveolar bone defects with the help of a surgical guide. Material and methods Six cone‐beam computed tomography scans of patients requiring horizon…
View article: Antimicrobial Mechanisms of Leucocyte- and Platelet Rich Fibrin Exudate Against Planktonic Porphyromonas gingivalis and Within Multi-Species Biofilm: A Pilot Study
Antimicrobial Mechanisms of Leucocyte- and Platelet Rich Fibrin Exudate Against Planktonic Porphyromonas gingivalis and Within Multi-Species Biofilm: A Pilot Study Open
Leucocyte- and platelet rich fibrin (L-PRF) is an autologous biomaterial used in regenerative procedures. It has an antimicrobial activity against P. gingivalis although the mechanism is not fully understood. It was hypothesized that L-PRF…
View article: Effect of different platelet‐rich fibrin matrices for ridge preservation in multiple tooth extractions: A split‐mouth randomized controlled clinical trial
Effect of different platelet‐rich fibrin matrices for ridge preservation in multiple tooth extractions: A split‐mouth randomized controlled clinical trial Open
Aim To evaluate dimensional changes in the alveolar ridge and bone structure after tooth extraction when L‐PRF or A‐PRF+ was used in comparison to unassisted socket healing. Materials and methods Twenty patients in need of at least three t…
View article: Impact of g force and timing on the characteristics of platelet-rich fibrin matrices
Impact of g force and timing on the characteristics of platelet-rich fibrin matrices Open
Recently, new centrifugation protocols for the preparation of platelet-rich fibrin (PRF) have been introduced in an attempt to further improve the beneficial impact of these 2nd generation platelet concentrate membranes. This in-vitro stud…
View article: Interaction between Different Implant Surfaces and Liquid Fibrinogen: A Pilot In Vitro Experiment
Interaction between Different Implant Surfaces and Liquid Fibrinogen: A Pilot In Vitro Experiment Open
Background . Platelet concentrates like leucocyte‐ and platelet‐rich fibrin (L‐PRF) have been widely evaluated in different oral surgical procedures to promote the healing process. However, liquid L‐PRF products such as liquid fibrinogen h…
View article: Potential prebiotic substrates modulate composition, metabolism, virulence and inflammatory potential of an in vitro multi-species oral biofilm
Potential prebiotic substrates modulate composition, metabolism, virulence and inflammatory potential of an in vitro multi-species oral biofilm Open
Background: Modulation of the commensal oral microbiota constitutes a promising preventive/therapeutic approach in oral healthcare. The use of prebiotics for maintaining/restoring the health-associated homeostasis of the oral microbiota ha…
View article: Alternative therapies in controlling oral malodour: a systematic review
Alternative therapies in controlling oral malodour: a systematic review Open
Is there a role for alternative therapies in controlling intra-oral halitosis? Treatments other than tongue cleaning and anti-halitosis products containing zinc, chlorhexidine and cetylpyridinium chloride were considered as alternative the…
View article: 3‐year follow‐up of the NobelActive implant
3‐year follow‐up of the NobelActive implant Open
Background: The NobelActive implant was introduced in 2008. It was developed and designed to improve primary implant stability and to prevent marginal bone loss. Despite being on the market for more than a decade, there are only a few stud…
View article: Comparison of a polyethylene glycol membrane and a collagen membrane for the treatment of bone dehiscence defects at bone level implants—A prospective, randomized, controlled, multicenter clinical trial
Comparison of a polyethylene glycol membrane and a collagen membrane for the treatment of bone dehiscence defects at bone level implants—A prospective, randomized, controlled, multicenter clinical trial Open
Objectives The aim of the present randomized, controlled clinical multicenter trial was to compare a polyethylene glycol (PEG) and a native collagen membrane (BG) for simultaneous guided bone regeneration at bony dehiscence‐type defects ar…
View article: Antibiotic dosage prescribed in oral implant surgery: A meta-analysis of cross-sectional surveys
Antibiotic dosage prescribed in oral implant surgery: A meta-analysis of cross-sectional surveys Open
This study aimed to assess the dosage and types of antibiotics prescribed in oral implant surgery, compare them among the different subpopulations (country and prescription regimens) and against the evidence-based recommended dosage: a 2-g…
View article: Alveolar bone level at deciduous molars in Flemish children: A retrospective, radiographic study
Alveolar bone level at deciduous molars in Flemish children: A retrospective, radiographic study Open
Aim The aim of this retrospective radiographic study in Flemish children was to examine the bone level and bone loss around deciduous molars and factors influencing this. Materials and methods Two thousand eight hundred ninety six digital …
View article: The usage of a lactobacilli probiotic in the non‐surgical therapy of peri‐implantitis: A randomized pilot study
The usage of a lactobacilli probiotic in the non‐surgical therapy of peri‐implantitis: A randomized pilot study Open
Objectives Examine the clinical and microbiological benefits of a dual‐strain Lactobacillus reuteri probiotic on the non‐surgical therapy of initial peri‐implantitis. Materials and methods This randomized, double‐blind study targeted patie…
View article: A dual‐strain <i>Lactobacilli reuteri</i> probiotic improves the treatment of residual pockets: A randomized controlled clinical trial
A dual‐strain <i>Lactobacilli reuteri</i> probiotic improves the treatment of residual pockets: A randomized controlled clinical trial Open
Aim To examine the adjunctive effect of a Lactobacillus reuteri probiotic (ATCC PTA 5289 & DSM 17938) on the re‐instrumentation of residual pockets. Materials and Methods This randomized, double‐blind, placebo‐controlled study included 39 …
View article: A randomized controlled clinical trail on the use of the L‐PRF block compared with DBBM in lateral sinus floor elevation
A randomized controlled clinical trail on the use of the L‐PRF block compared with DBBM in lateral sinus floor elevation Open
Background The use of platelet concentrates in sinus lift procedures, like Leucocyte and Platelet Rich Fibrin (L-PRF), has increased in the last few years. One of the interesting properties of L-PRF is the presence of platelets and their i…