Marc Zumberg
YOU?
Author Swipe
View article: Validation and clinical application of the hereditary hemorrhagic telangiectasia-specific quality of life scale
Validation and clinical application of the hereditary hemorrhagic telangiectasia-specific quality of life scale Open
This study successfully externally validates the HHT-QoL. The HHT-QoL is a validated disease-specific HRQoL instrument with defined severity classification and minimal clinically important difference, making it ideal for use in clinical tr…
View article: Nasal RADA16 hydrogel application decreases epistaxis severity scores in adults with hereditary hemorrhagic telangiectasia
Nasal RADA16 hydrogel application decreases epistaxis severity scores in adults with hereditary hemorrhagic telangiectasia Open
View article: Silastic Septal Splints in the Management of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia
Silastic Septal Splints in the Management of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia Open
View article: Case report: Novel homozygous ACVRL1 missense variant in a family with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension: findings suggest a hypomorphic allele
Case report: Novel homozygous ACVRL1 missense variant in a family with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension: findings suggest a hypomorphic allele Open
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder caused by pathogenic variants in genes within the transforming growth factor beta (TGF-β) signaling pathway, such as ACVRL1 , leading to haploinsufficie…
View article: Abdominal pain in a patient with epistaxis, telangiectasias, and arteriovenous malformations
Abdominal pain in a patient with epistaxis, telangiectasias, and arteriovenous malformations Open
View article: A Cohort, Semi-Randomized, Open Label Quality Improvement Patient Blood Management (PBM) Comparison of Point of Care Viscoelastic Coagulation Monitors in Cardiac Surgery
A Cohort, Semi-Randomized, Open Label Quality Improvement Patient Blood Management (PBM) Comparison of Point of Care Viscoelastic Coagulation Monitors in Cardiac Surgery Open
Purpose: Viscoelastic testing (VET), recommended for heart surgery, has not been adopted due to lack of timely point of care (POC) technology. Several POC VET devices have become available. The purposes of this quality initiative (QI), par…
View article: PATH-HHT, a Double-Blind, Randomized, Placebo-Controlled Trial in Hereditary Hemorrhagic Telangiectasia Demonstrates That Pomalidomide Reduces Epistaxis and Improves Quality of Life
PATH-HHT, a Double-Blind, Randomized, Placebo-Controlled Trial in Hereditary Hemorrhagic Telangiectasia Demonstrates That Pomalidomide Reduces Epistaxis and Improves Quality of Life Open
Introduction Hereditary hemorrhagic telangiectasia (HHT), the second most common bleeding disorder worldwide, affects 1 in 5000 people and is characterized by extensive formation of telangiectasia and arteriovenous malformations (AVM) in m…
View article: Consensus recommendations on peripheral blood smear review: defining curricular standards and fellow competency
Consensus recommendations on peripheral blood smear review: defining curricular standards and fellow competency Open
Graduate medical education training in hematology in North America is accredited by the Accreditation Council for Graduate Medical Education (ACGME). Trainees routinely review peripheral blood smears (PBS) in providing clinical care. Compe…
View article: COVID-19 Associated Micro-Anastomotic Thrombosis After Abdominal Free Tissue Transfer: A Case Report and Literature Review
COVID-19 Associated Micro-Anastomotic Thrombosis After Abdominal Free Tissue Transfer: A Case Report and Literature Review Open
The hypercoagulable state of COVID-19 infection presents a challenge to microsurgeons. While the American Society of Anesthesiologists recommends deferring surgery for 4–10 weeks for COVID-19-infected patients, little else is known regardi…
View article: <i>Committee Corner</i> Systems-Based Hematology: Where We Have Been and Where We Are Going
<i>Committee Corner</i> Systems-Based Hematology: Where We Have Been and Where We Are Going Open
View article: Use of cell salvage and HBOC-201 in a pregnant Jehovah’s Witness with sickle beta+thalassaemia undergoing emergency caesarean section
Use of cell salvage and HBOC-201 in a pregnant Jehovah’s Witness with sickle beta+thalassaemia undergoing emergency caesarean section Open
Patients with severe anaemia who refuse or cannot safely receive red cell transfusion present challenges during pregnancy, delivery and the postpartum period. Strategies including HBOC-201 (Hemopure) and intraoperative use of cell salvage …
View article: A Case of Acquired Hemophilia A and Congenital Hemophilia B
A Case of Acquired Hemophilia A and Congenital Hemophilia B Open
View article: Evidence-Based Minireview: Should warfarin or a direct oral anticoagulant be used in patients presenting with thrombosis in the splanchnic or cerebral veins?
Evidence-Based Minireview: Should warfarin or a direct oral anticoagulant be used in patients presenting with thrombosis in the splanchnic or cerebral veins? Open
Case 1: A 23-year-old female third-year medical student who has no medical history seeks treatment for abdominal distention. She takes an estrogen-containing birth control pill and does not smoke or consume alcohol. Family history is unrem…
View article: Clots in unusual places: lots of stress, limited data, critical decisions
Clots in unusual places: lots of stress, limited data, critical decisions Open
Although much less common than deep vein thrombosis of the lower extremities or lungs, clots in unusual locations, including the splanchnic, cerebral, retinal, upper-extremity, and renal locations, present with significant morbidity and mo…
View article: Systems-based hematology: highlighting successes and next steps
Systems-based hematology: highlighting successes and next steps Open
Systems-based hematology is dedicated to improving care delivery for patients with blood disorders. First defined by the American Society of Hematology in 2015, the idea of a systems-based hematologist arose from evolving pressures in the …
View article: Bleeding and Thrombotic Risk in Low Dose Heparin Infusion as Compared to Standard Dose Heparin Infusion
Bleeding and Thrombotic Risk in Low Dose Heparin Infusion as Compared to Standard Dose Heparin Infusion Open
View article: A case study of 10 patients administered HBOC‐201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option
A case study of 10 patients administered HBOC‐201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option Open
BACKGROUND Hemoglobin‐Based Oxygen Carriers (HBOCs) can act as an “oxygen bridge” in acute severe anemia when transfusion is indicated, but not possible. We present data on 10 Expanded Access (EA) patients treated with high cumulative dose…
View article: A Patient-Centered Emergency Department Management Strategy for Sickle-Cell Disease Super-Utilizers
A Patient-Centered Emergency Department Management Strategy for Sickle-Cell Disease Super-Utilizers Open
This effort suggests that a targeted approach is both feasible and potentially effective, laying a foundation for broader study.
View article: Management of granulomatous lymphocytic interstitial lung disease in a patient with common variable immune deficiency
Management of granulomatous lymphocytic interstitial lung disease in a patient with common variable immune deficiency Open
A 61-year-old woman presented with longstanding cough and progressive dyspnoea. She underwent an extensive evaluation and was diagnosed with common variable immunodeficiency (CVID) with granulomatous lymphocytic interstitial lung disease (…
View article: Successful Implementation of a Packed Red Blood Cell and Fresh Frozen Plasma Transfusion Protocol in the Surgical Intensive Care Unit
Successful Implementation of a Packed Red Blood Cell and Fresh Frozen Plasma Transfusion Protocol in the Surgical Intensive Care Unit Open
Implementation of a restrictive transfusion protocol can effectively reduce blood product utilization in critically ill surgical patients with no increase in morbidity or mortality.
View article: Feasibility of Extended‐interval Follow‐up for Patients Receiving Warfarin
Feasibility of Extended‐interval Follow‐up for Patients Receiving Warfarin Open
Summary Aims The 2012 American College of Chest Physician Evidence‐Based Management of Anticoagulant Therapy guidelines suggest an international normalized ratio ( INR ) testing interval of up to 12 weeks, rather than every 4 weeks, for pa…