Marcel E. Salive
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View article: Proceedings of the Alzheimer’s Diagnosis in Older Adults With Chronic Conditions Network Inaugural Annual Conference
Proceedings of the Alzheimer’s Diagnosis in Older Adults With Chronic Conditions Network Inaugural Annual Conference Open
The Alzheimer’s Disease in Older Adults with Chronic Conditions (ADACC) Network is funded by the National Institute on Aging as a U24 cooperative agreement. ADACC is an inclusive, multidisciplinary group across multiple institutions that i…
View article: Long-term impact of Diabetes Prevention Program interventions on walking endurance
Long-term impact of Diabetes Prevention Program interventions on walking endurance Open
Objectives Type 2 diabetes (T2D) and prediabetes are associated with poor walking endurance, a marker of physical function. We aimed to examine the long-term effects of metformin or intensive lifestyle intervention in adults at high risk o…
View article: THE IMPACT OF AN INTENSIVE LIFESTYLE INTERVENTION IN TYPE 2 DIABETES ON LONG-TERM MULTIMORBIDITY
THE IMPACT OF AN INTENSIVE LIFESTYLE INTERVENTION IN TYPE 2 DIABETES ON LONG-TERM MULTIMORBIDITY Open
Multimorbidity, or the accumulation of multiple chronic diseases, is an important clinical issue in aging and is associated with geriatric syndromes, physical and cognitive function declines, increased health care costs, and poorer health-…
View article: Emerging approaches to multiple chronic condition assessment
Emerging approaches to multiple chronic condition assessment Open
Older adults experience a higher prevalence of multiple chronic conditions (MCCs). Establishing the presence and pattern of MCCs in individuals or populations is important for healthcare delivery, research, and policy. This report describe…
View article: National Institutes of Health Advancing Multimorbidity Research
National Institutes of Health Advancing Multimorbidity Research Open
Background: Multimorbidity, the co-occurrence of 2 or more chronic diseases, is more common than having a single chronic disease, especially among persons age 65 years and older. The routine measurement of multimorbidity can facilitate a b…
View article: Body Clock: Matching Personalized Multimorbidity and Fast Aging Using Information Entropy
Body Clock: Matching Personalized Multimorbidity and Fast Aging Using Information Entropy Open
With aging, most older adults are at risk of having more than two diseases, conventionally defined as multimorbidity. We determined body organ disease number (BODN) as a new multimorbidity index. We measured the degree to which each diseas…
View article: Prioritized Research for the Prevention, Treatment, and Reversal of Chronic Disease: Recommendations From the Lifestyle Medicine Research Summit
Prioritized Research for the Prevention, Treatment, and Reversal of Chronic Disease: Recommendations From the Lifestyle Medicine Research Summit Open
Declining life expectancy and increasing all-cause mortality in the United States have been associated with unhealthy behaviors, socioecological factors, and preventable disease. A growing body of basic science, clinical research, and popu…
View article: Accelerating the Search for Interventions Aimed at Expanding the Health Span in Humans: The Role of Epidemiology
Accelerating the Search for Interventions Aimed at Expanding the Health Span in Humans: The Role of Epidemiology Open
Background Extensive work in basic and clinical science suggests that biological mechanisms of aging are causally related to the development of disease and disability in late life. Modulation of the biological mechanisms of aging can exten…
View article: MULTIMORBIDITY AND MATCHING THE INSTRUMENT AND PURPOSE: CHALLENGES, PITFALLS, AND GAPS
MULTIMORBIDITY AND MATCHING THE INSTRUMENT AND PURPOSE: CHALLENGES, PITFALLS, AND GAPS Open
Many different approaches have been developed to measure multimorbidity (MM; >2 chronic conditions) in clinical research and practice, public health and population studies. The purpose of measuring MM includes taking clinical actions, heal…