Marcel Ebeling
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View article: Risk profile for recurrence after interdisciplinary treatment of odontogenic maxillary sinusitis: experience of a single centre
Risk profile for recurrence after interdisciplinary treatment of odontogenic maxillary sinusitis: experience of a single centre Open
Despite a moderate recurrence rate, no significant patient-specific, anatomical, or procedure-specific predictors of recurrence were identified. These findings emphasize the importance of individualized treatment planning and interdiscipli…
View article: Stratifying Skin Cancer Patients and Guiding Treatment Decisions Through Combined p53 and p63 Expression Analysis
Stratifying Skin Cancer Patients and Guiding Treatment Decisions Through Combined p53 and p63 Expression Analysis Open
Distinct expression patterns of p53 and p63 suggest stage-specific roles in skin carcinogenesis. Elevated p53 in early lesions supports its tumor-suppressive function, while p63 may contribute to tumor maintenance in advanced stages. These…
View article: Factors influencing recurrence after in-hospital treatment of odontogenic-related oromaxillofacial infections: a single-centre experience
Factors influencing recurrence after in-hospital treatment of odontogenic-related oromaxillofacial infections: a single-centre experience Open
Purpose Evidence regarding specific factors influencing recurrence after treatment of oromaxillofacial infections is limited. This study aimed to evaluate the incidence and identify predictors of recurrence following in-hospital treatment.…
View article: Opportunities for the further development of the Safety Case for deep geological repositories by transdisciplinary research – FEP catalogs and scenario development
Opportunities for the further development of the Safety Case for deep geological repositories by transdisciplinary research – FEP catalogs and scenario development Open
In the TRANSENS research project (2019–2025), large-scale transdisciplinary research on nuclear waste management is being conducted for the first time in Germany. Transdisciplinary in this context means that non-specialists and practice ac…
View article: Evaluation of Five-year Overall Survival Rates Among 18,331 Head and Neck Cancer Patients Exposed to Different Targeted Therapies Through Real-world Data in a Case-controlled Study
Evaluation of Five-year Overall Survival Rates Among 18,331 Head and Neck Cancer Patients Exposed to Different Targeted Therapies Through Real-world Data in a Case-controlled Study Open
EGFR inhibitors are one of the most frequently used targeted therapies in HNC. However, in the present analysis, a survival advantage of patients treated with c-MET inhibitors or VEGF inhibitors was observed compared to those treated with …
View article: Porcine-derived Acellular Dermal Matrix for Temporary Soft Tissue Coverage in Locally Advanced Angiosarcoma of the Face – A Soft Tissue Odyssey?
Porcine-derived Acellular Dermal Matrix for Temporary Soft Tissue Coverage in Locally Advanced Angiosarcoma of the Face – A Soft Tissue Odyssey? Open
BACKGROUND/AIM: Angiosarcomas of the face are rare but present significant treatment challenges due to their origin in the supportive tissues of blood or lymphatic vessels. Achieving optimal balance between oncological efficacy and aesthet…
View article: Extracranial Hypoglossal Schwannoma: Case Report and Literature Review
Extracranial Hypoglossal Schwannoma: Case Report and Literature Review Open
Accurate diagnosis of this rare clinical entity requires comprehensive diagnostics. The optimal therapeutic strategy is nerve-sparing surgical excision, although it can be challenging.
View article: Fibula Grafting for Oromandibular Reconstruction and its Effect on Patient Quality of Life - A Scoping Review
Fibula Grafting for Oromandibular Reconstruction and its Effect on Patient Quality of Life - A Scoping Review Open
Fibula osteoseptocutaneous flap has been widely used for oncologic bony reconstruction of both the mandible and maxilla. Early and late morbidities of the donor side such as leg weakness, ankle instability, limited ankle mobility, tibial s…
View article: Elevating Precision Oncology: Unraveling the Role of microRNA Analysis in the Comprehensive Staging of Oral Cavity Carcinoma
Elevating Precision Oncology: Unraveling the Role of microRNA Analysis in the Comprehensive Staging of Oral Cavity Carcinoma Open
This letter emphasizes the potential of microRNA (miRNA) analysis in the staging of oral cavity carcinoma. It highlights the role of miRNA analysis in predicting critical aspects, such as lymphonodular recurrence, preoperative tumor gradin…
View article: Comparison of the Effective Radiation Dose in the Region of the Facial Skull Between Multidetector CT, Dental Conebeam CT and Intraoperative 3D C-Arms
Comparison of the Effective Radiation Dose in the Region of the Facial Skull Between Multidetector CT, Dental Conebeam CT and Intraoperative 3D C-Arms Open
Study Design Experimental single-centre study of X-ray absorption using a phantom skull. Objective This experimental study aimed to compare the radiation doses of different 3D imaging devices used in maxillofacial surgery, including one Mu…
View article: Chernobyl’s Aftermath: Multiple Manifestations of Basalioma in a Patient after Radioactive Contamination in 1986
Chernobyl’s Aftermath: Multiple Manifestations of Basalioma in a Patient after Radioactive Contamination in 1986 Open
Background: The Chernobyl nuclear disaster is still considered the worst nuclear accident in history. The particles were dispersed over the former USSR and large parts of Western Europe, leading to radioactive exposure to more than 10 mill…
View article: Airway Management of Orofacial Infections Originating in the Mandible
Airway Management of Orofacial Infections Originating in the Mandible Open
The primary aim of this study was to assess the incidence of a difficult airway and emergency tracheostomy in patients with orofacial infections originating in the mandible, and a secondary aim was to determine the potential predictors of …
View article: Factors Influencing Recurrence after Surgical Treatment of Odontogenic Maxillary Sinusitis: An Analysis from the Oral and Maxillofacial Surgery Point of View
Factors Influencing Recurrence after Surgical Treatment of Odontogenic Maxillary Sinusitis: An Analysis from the Oral and Maxillofacial Surgery Point of View Open
The aim of the study was to determine the factors influencing the development of recurrence after the surgical treatment of odontogenic maxillary sinusitis in an oral and maxillofacial surgery clinic over a 7-year period. Demographic and a…
View article: Justification of Indication for Cranial CT Imaging after Mild Traumatic Brain Injury According to the Current National Guidelines
Justification of Indication for Cranial CT Imaging after Mild Traumatic Brain Injury According to the Current National Guidelines Open
The primary aim was to evaluate the compliance of cranial CT indication with the national guideline-based decision rules in patients after mTBI. The secondary aim was to determine the incidence of CT pathologies among justified and unjusti…
View article: Clinical Indicators for Primary Cranial CT Imaging after Mild Traumatic Brain Injury—A Retrospective Analysis
Clinical Indicators for Primary Cranial CT Imaging after Mild Traumatic Brain Injury—A Retrospective Analysis Open
The primary aim was to determine the clinical indicators for primary cranial CT imaging in patients after mild traumatic brain injury (mTBI). The secondary aim was to evaluate the need for post-traumatic short-term hospitalization based on…
View article: Comparison of Anatomical Preformed Titanium Implants and Patient-Specific CAD/CAM Implants in the Primary Reconstruction of Isolated Orbital Fractures—A Retrospective Study
Comparison of Anatomical Preformed Titanium Implants and Patient-Specific CAD/CAM Implants in the Primary Reconstruction of Isolated Orbital Fractures—A Retrospective Study Open
Background/Aim: Reconstruction of the fractured orbit remains a challenge. The aim of this study was to compare anatomical preformed titanium orbital implants with patient-specific CAD/CAM implants for precision and intraoperative applicab…
View article: Dental Root Injuries Caused by Osteosynthesis Screws in Orthognathic Surgery—Comparison of Conventional Osteosynthesis and Osteosynthesis by CAD/CAM Drill Guides and Patient-Specific Implants
Dental Root Injuries Caused by Osteosynthesis Screws in Orthognathic Surgery—Comparison of Conventional Osteosynthesis and Osteosynthesis by CAD/CAM Drill Guides and Patient-Specific Implants Open
Background/Aim: The primary aim was to evaluate the prevalence and localisation of dental injuries caused by osteosynthesis screws during orthognathic surgery, comparing two different CAD/CAM planning/surgical approaches through retrospect…
View article: Comparison of Laser-Sintered and Milled Patient-Specific Reconstruction Plates for Complications and Outcomes in Mandibular Defects—Comparative Analysis of a Single-Center Cohort
Comparison of Laser-Sintered and Milled Patient-Specific Reconstruction Plates for Complications and Outcomes in Mandibular Defects—Comparative Analysis of a Single-Center Cohort Open
CAD/CAM-manufactured implants are increasingly becoming the standard in current therapy. The question of whether the manufacturing-related rougher surface of selective laser fusion plates compared to milled, smoother reconstruction plates …
View article: MRONJ of the Mandible—From Decortication to a Complex Jaw Reconstruction Using a CAD/CAM-Guided Bilateral Scapula Flap
MRONJ of the Mandible—From Decortication to a Complex Jaw Reconstruction Using a CAD/CAM-Guided Bilateral Scapula Flap Open
Medication-related osteonecrosis of the jaw (MRONJ) has been an integral part of the maxillofacial patient population for some time. The therapeutic concept ranges from conservative approaches over less extended decortications to major jaw…
View article: First-Hand Experience and Result with New Robot-Assisted Laser LeFort-I Osteotomy in Orthognathic Surgery: A Case Report
First-Hand Experience and Result with New Robot-Assisted Laser LeFort-I Osteotomy in Orthognathic Surgery: A Case Report Open
Background: We report the world’s first developer-independent experience with robot-assisted laser Le Fort I osteotomy (LLFO) and drill-hole marking in orthognathic surgery. To overcome the geometric limitations of conventional rotating an…
View article: Transdisciplinary research on repository safety: challenges and opportunities
Transdisciplinary research on repository safety: challenges and opportunities Open
Since 2019, transdisciplinary research on the scientifically challenging and often controversially debated topic of nuclear waste management on a larger scale has been carried out for the first time in Germany within the co-operative proje…