Explanipedia

Risk of new HIV diagnosis by intersecting migration, socioeconomic, and mental health vulnerabilities in the Netherlands: a nationwide analysis of the ATHENA cohort and Statistics Netherlands registry data Open

Patrizia Carrieri, Nina Schat, Selwyn H. Lowe, Marit G. A. van Vonderen, Mark D. Verhagen , et al. · 2025

A Robust Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)–Specific T- and B-Cell Response Is Associated With Early Viral Clearance in SARS-CoV-2 Omicron-Infected Immunocompromised Individuals Open

Magda Vergouwe, Jason J. Biemond, Karlijn van der Straten, Lisa van Pul, Gius Kerster , et al. · 2024

Background The immunological determinants of delayed viral clearance and intrahost viral evolution that drive the development of new pathogenic virus strains in immunocompromised individuals are unknown. Therefore, we longitudinally studie…

Clinical and humoral response after SARS-CoV-2 breakthrough infection in patients receiving immunosuppressant therapy Open

Eileen W Stalman, Luuk Wieske, Jim Keijser, Koos P J van Dam, Laura Kummer , et al. · 2024

DengueSeq: a pan-serotype whole genome amplicon sequencing protocol for dengue virus Open

Chantal B. F. Vogels, Verity Hill, Mallery I. Breban, Chrispin Chaguza, Lauren M. Paul , et al. · 2024

Circulation, viral diversity and genomic rearrangement in mpox virus in the Netherlands during the 2022 outbreak and beyond Open

Leonard Schuele, Marjan Boter, David F. Nieuwenhuijse, Hannelore M Götz, Ewout Fanoy , et al. · 2024

Mpox is an emerging zoonotic disease which has now spread to over 113 countries as of August 2023, with over 89,500 confirmed human cases. The Netherlands had one of the highest incidence rates in Europe during the peak of the outbreak. In…

DengueSeq: A pan-serotype whole genome amplicon sequencing protocol for dengue virus Open

Chantal B. F. Vogels, Verity Hill, Mallery I. Breban, Chrispin Chaguza, Lauren M. Paul , et al. · 2023

Background The increasing burden of dengue virus on public health due to more explosive and frequent outbreaks highlights the need for improved surveillance and control. Genomic surveillance of dengue virus not only provides important insi…

Mpox outbreak among men who have sex with men in Amsterdam and Rotterdam, the Netherlands: no evidence for undetected transmission prior to May 2022, a retrospective study Open

Henry J.C. de Vries, Hannelore M Götz, Sylvia M. Bruisten, Annemiek A. van der Eijk, Maria Prins , et al. · 2023

Since May 2022, over 21,000 mpox cases have been reported from 29 EU/EEA countries, predominantly among men who have sex with men (MSM). The Netherlands was the fourth most affected country in Europe, with more than 1,200 cases and a crude…

A comparison of five Illumina, Ion Torrent, and nanopore sequencing technology-based approaches for whole genome sequencing of SARS-CoV-2 Open

Ellen C. Carbo, Kees Mourik, Stefan A. Boers, Bas B. Oude Munnink, David F. Nieuwenhuijse , et al. · 2023

External validation of the PAGE-B score for HCC risk prediction in people living with HIV/HBV coinfection Open

Bernard Surial, Adrià Ramírez Mena, Marie Roumet, Andreas Limacher, Colette Smit , et al. · 2023

Longitudinal Dynamics of the SARS-CoV-2 Antibody Repertoire after SARS-CoV-2 Delta and Omicron Breakthrough Infections in Patients with Immune-Mediated Inflammatory Diseases Open

Eileen W Stalman, Luuk Wieske, Jim Keijser, PJ van Dam, Laura Kummer , et al. · 2023

Human Monkeypox Virus outbreak among Men who have Sex with Men in Amsterdam and Rotterdam, the Netherlands: no evidence for undetected transmission prior to May 2022 in a retrospective study Open

Henry J.C. de Vries, Hannelore M Götz, Sylvia M. Bruisten, Annemiek A. van der Eijk, Maria Prins , et al. · 2022

Since May 2022 over 20.000 human monkeypox virus (hMPXV) cases have been reported from 29 EU/EEA countries, predominantly among men who have sex with men. With over 1200 cases, and a crude notification rate of 70.7 per million population, …

Development of Resistance-Associated Mutations After Sotrovimab Administration in High-risk Individuals Infected With the SARS-CoV-2 Omicron Variant Open

Emma Birnie, Jason J. Biemond, Brent Appelman, Godelieve J. de Bree, Marcel Jonges , et al. · 2022

This study investigates whether resistance-associated mutations develop after treatment with sotrovimab in high-risk patients infected with the SARS-CoV-2 Omicron variant.

Paediatric monkeypox patient with unknown source of infection, the Netherlands, June 2022 Open

A. Marceline van Furth, Martijn van der Kuip, Anne L van, Lydia CR Fievez, Gini GC van Rijckevorsel , et al. · 2022

Since May 2022, an international monkeypox (MPX) outbreak has been ongoing in more than 50 countries. While most cases are men who have sex with men, transmission is not restricted to this population. In this report, we describe the case o…

Monkeypox virus whole genome sequencing using combination of NextGenPCR and Oxford Nanopore v1 Open

Matthijs R. A. Welkers, Marcel Jonges, Anton van den Ouden · 2022

Rapid genomic surveillance of monkeypox virus (MPXV) can provide valuable insights in order to guide public health interventions. Current sequencing protocols make use of direct Oxford Nanopore Sequencing. However, the obtained depth is a …

Controlling a human parainfluenza virus-3 outbreak in a haematology ward in a tertiary hospital: the importance of screening strategy and molecular diagnostics in relation to clinical symptoms Open

Zsὁfia Iglὁi, Inge H. M. van Loo, A. M. P. Demandt, Karen Franssen, Marcel Jonges , et al. · 2022

Epidemiologic and Genomic Analysis of SARS-CoV-2 Delta Variant Superspreading Event in Nightclub, the Netherlands, June 2021 Open

Jelle Koopsen, Catharina E van Ewijk, Roisin Bavalia, Akke Cornelissen, Sylvia M. Bruisten , et al. · 2022

We report a severe acute respiratory syndrome coronavirus 2 superspreading event in the Netherlands after distancing rules were lifted in nightclubs, despite requiring a negative test or vaccination. This occurrence illustrates the potenti…

Risk of SARS-CoV-2 transmission upon return to work in RNA-positive healthcare workers Open

Lisa M. Kolodziej, Sophie Hordijk, Jelle Koopsen, Jaap Maas, H.T. Thung , et al. · 2022

A Comparison of Five Illumina, Ion Torrent, and Nanopore Sequencing Technology-Based Approaches for Whole Genome Sequencing of Sars-Cov-2 Open

Ellen Catharine Carbo, Kees Mourik, Stefan A. Boers, Bas B. Oude Munnink, David F. Nieuwenhuijse , et al. · 2022

A single mRNA vaccine dose in COVID-19 patients boosts neutralizing antibodies against SARS-CoV-2 and variants of concern Open

Marit J. van Gils, Hugo D.G. van Willigen, Elke Wynberg, Alvin X. Han, Karlijn van der Straten , et al. · 2021

Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021 Open

Richard Molenkamp, Ewout Fanoy, Leonie Derickx, Theun de Groot, Marcel Jonges , et al. · 2021

We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta v…

Rapid reinfection with SARS-CoV-2 variant-of-concern Alpha detected in a nurse during an outbreak at a non-covid inpatient ward: lessons learned Open

Jelle Koopsen, Mireille Dekker, Philip Thung, Marcel Jonges, Harry Vennema , et al. · 2021

Serologic Surveillance and Phylogenetic Analysis of SARS-CoV-2 Infection Among Hospital Health Care Workers Open

Jonne J. Sikkens, David T. P. Buis, Edgar Peters, Mireille Dekker, Michiel Schinkel , et al. · 2021

This study found that HCWs working on COVID-19 wards were at increased risk for nosocomial SARS-CoV-2 infection with an important role for HCW-to-HCW transmission. These findings suggest that infection among HCWs deserves more consideratio…

Simultaneous detection and ribotyping of Clostridioides difficile, and toxin gene detection directly on fecal samples Open

Tessel M. van Rossen, Joffrey van Prehn, Alex Koek, Marcel Jonges, Robin van Houdt , et al. · 2021

Background Clostridioides difficile is the most common cause of nosocomial diarrhea. Ribotyping of cultured strains by a PCR-based test is used to study potential transmission between patients. We aimed to develop a rapid test that can be …

Serologic Surveillance and Phylogenetic Analysis of SARS-CoV-2 Infection in Hospital Health Care Workers Open

Jonne J. Sikkens, David T.P. Buis, Edgar J.G. Peters, Mireille Dekker, Michiel Schinkel , et al. · 2021

BACKGROUND It is unclear how, when and where health care workers (HCW) working in hospitals are infected with SARS-CoV-2. METHODS Prospective cohort study comprising 4-weekly measurement of SARS-CoV-2 specific antibodies and questionnaires…

Simultaneous detection and ribotyping of Clostridioides difficile, and toxin gene detection directly on fecal samples Open

Tessel M. van Rossen, Joffrey van Prehn, Alex Koek, Marcel Jonges, Robin van Houdt , et al. · 2021

Background: Clostridioides difficile is the most common cause of nosocomial diarrhea. Ribotyping of cultured strains by a PCR-based test is used to study potential transmission between patients. We aimed to develop a rapid test that can be…

Value of SARS-COV-2 genomic characterization in elucidating within-hospital transmission Open

L M Cadenau, Matthijs R. A. Welkers, Marcel Jonges, Janke Schinkel, Ingrid J. B. Spijkerman , et al. · 2021

HCV micro-elimination in individuals with HIV in the Netherlands 4 years after universal access to direct-acting antivirals: a retrospective cohort study Open

Colette Smit, Anders Boyd, Bart Rijnders, Thijs van de Laar, Eliane M.S. Leyten , et al. · 2020

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure Open

F. Xavier López‐Labrador, Julianne R. Brown, Nicole Fischer, Heli Harvala, Sander van Boheemen , et al. · 2020

Simultaneous detection and ribotyping of Clostridioides difficile, and toxin gene detection directly on fecal samples Open

Tessel M. van Rossen, Joffrey van Prehn, Alex Koek, Marcel Jonges, Robin van Houdt , et al. · 2020

Background: Clostridioides difficile is the most common cause of nosocomial diarrhea. Ribotyping of cultured strains by a PCR-based test is used to study potential transmission between patients. We aimed to develop a rapid test that can be…

Exploring the use of influenza virus sequence diversity for the identification and characterization of transmission events Open

Marcel Jonges · 2015

markdownabstractAbstract \n \nIn this thesis we evaluate the use of influenza sequence diversity to support outbreak control measures. Specifically, we investigated the possibility of identifying clustered influenza virus cases as well as …

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