Marcel Leroi
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View article: A multi-hospital, clinician-initiated bacterial genomics programme to investigate treatment failure in severe Staphylococcus aureus infections
A multi-hospital, clinician-initiated bacterial genomics programme to investigate treatment failure in severe Staphylococcus aureus infections Open
Bacterial genomics is increasingly used for infectious diseases surveillance, outbreak detection and prediction of antibiotic resistance. With expanding availability of rapid whole-genome sequencing, bacterial genomics data could become a …
View article: A multi-hospital, clinician-initiated bacterial genomics program to investigate treatment failure in severe<i>Staphylococcus aureus</i>infections
A multi-hospital, clinician-initiated bacterial genomics program to investigate treatment failure in severe<i>Staphylococcus aureus</i>infections Open
Bacterial genomics is increasingly used for infectious diseases surveillance, outbreak control and prediction of antibiotic resistance. With expanding availability of rapid whole-genome sequencing, bacterial genomics data could become a va…
View article: A multi-site, international laboratory study to assess the performance of penicillin susceptibility testing of <i>Staphylococcus aureus</i>
A multi-site, international laboratory study to assess the performance of penicillin susceptibility testing of <i>Staphylococcus aureus</i> Open
Objectives There is clinical uncertainty over the optimal treatment for penicillin-susceptible Staphylococcus aureus (PSSA) infections. Furthermore, there is concern that phenotypic penicillin susceptibility testing methods are not reliabl…
View article: Diagnosis of septic arthritis in the acute care setting: the value of routine intra-operative sample culture
Diagnosis of septic arthritis in the acute care setting: the value of routine intra-operative sample culture Open
Objective Diagnosing septic arthritis can be challenging and frequently involves clinical assessment, laboratory investigations and synovial fluid analysis. We sought to determine the utility of synovial aspiration and intra-operative syno…
View article: ICE volume 42 issue 5 Cover and Front matter
ICE volume 42 issue 5 Cover and Front matter Open
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View article: A Simple Cleaning Intervention to Prevent Transmission of Carbapenemase-Producing Enterobacterales from Hospital Sinks
A Simple Cleaning Intervention to Prevent Transmission of Carbapenemase-Producing Enterobacterales from Hospital Sinks Open
Background: A prolonged outbreak of carbapenemase-producing Serratia marcescens (CPSM) was identified in our quaternary healthcare center over a 2-year period from 2015 through 2017. A reservoir of IMP-4–producing S. marcescens in sink dra…
View article: Case Report: Confirmation by Metagenomic Sequencing of Visceral Leishmaniasis in an Immunosuppressed Returned Traveler
Case Report: Confirmation by Metagenomic Sequencing of Visceral Leishmaniasis in an Immunosuppressed Returned Traveler Open
There has been increased interest in using metagenomic next-generation sequencing as an unbiased approach for diagnosing infectious diseases. We describe a 61-year-old man on fingolimod therapy for multiple sclerosis with an extensive trav…
View article: Genomic interrogation of the burden and transmission of multidrug-resistant pathogens within and across hospital networks
Genomic interrogation of the burden and transmission of multidrug-resistant pathogens within and across hospital networks Open
Background Multidrug-resistant organisms (MDROs) disproportionately affect hospitalized patients due to the combination of comorbidities, frequent antimicrobial use, and in-hospital MDRO transmission. Identification of MDRO transmission by…
View article: Severe Disease Caused by Community-Associated MRSA ST398 Type V, Australia, 2017
Severe Disease Caused by Community-Associated MRSA ST398 Type V, Australia, 2017 Open
Using whole-genome sequencing, we identified a community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) sequence type (ST) 398 type V (5C2&5) isolate (typically found in China) in Australia in 2017. This CA-MRSA ST398 var…