Marcel Mengelers
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View article: Exploring the relationship between daily intake and urinary excretion of the mycotoxins T-2 and HT-2 toxin in humans
Exploring the relationship between daily intake and urinary excretion of the mycotoxins T-2 and HT-2 toxin in humans Open
T-2 toxin (T-2) and HT-2 toxin (HT-2) are mycotoxins that can contaminate food, especially cereals. Exposure to T-2 and HT-2 has mainly been estimated using dietary exposure assessment, however, human biomonitoring presents another valuabl…
View article: Urinary concentrations of arsenic species in older Dutch adults and risk of chronic kidney disease
Urinary concentrations of arsenic species in older Dutch adults and risk of chronic kidney disease Open
Chronic exposure to arsenic (As) is associated with various cancers and nephrotoxicity. It occurs in different chemical forms which vary in toxicological potential. Human biomonitoring (HBM) is used to measure internal (all-route) exposure…
View article: Technical Report on the need for re‐evaluation of the safety of hexane used as an extraction solvent in the production of foodstuffs and food ingredients
Technical Report on the need for re‐evaluation of the safety of hexane used as an extraction solvent in the production of foodstuffs and food ingredients Open
Hexane (called ‘technical hexane’ in this report) is authorised for use as an extraction solvent in the production of foodstuffs and food ingredients under Directive 2009/32/EC. Following a request from the European Commission, EFSA assess…
View article: Safety assessment of the process Lietpak, based on the EREMA MPR technology, used to recycle post‐consumer PET into food contact materials
Safety assessment of the process Lietpak, based on the EREMA MPR technology, used to recycle post‐consumer PET into food contact materials Open
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process Lietpak (EU register number RECYC327), which uses the EREMA MPR technology. The input material is hot caustic washed a…
View article: Safety assessment of the process Guolong, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials
Safety assessment of the process Guolong, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials Open
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process Guolong (EU register number RECYC323), which uses the EREMA Basic technology. The input material is hot caustic washed…
View article: Safety assessment of the process Palamidis, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials
Safety assessment of the process Palamidis, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials Open
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process Palamidis (EU register number RECYC325), which uses the EREMA Basic technology. The input material is hot caustic wash…
View article: Safety evaluation of the food enzyme asparaginase from the genetically modified Aspergillus niger strain ASP
Safety evaluation of the food enzyme asparaginase from the genetically modified Aspergillus niger strain ASP Open
The food enzyme asparaginase (l‐asparagine amidohydrolase; EC 3.5.1.1) is produced with the genetically modified Aspergillus niger strain ASP by DSM Food Specialties B.V. The genetic modifications do not give rise to safety concerns. The f…
View article: Safety assessment of the process Ecopacking, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials
Safety assessment of the process Ecopacking, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials Open
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process Ecopacking (EU register number RECYC324), which uses the EREMA Basic technology. The input material is ■■■■■ washed an…
View article: Safety evaluation of an extension of use of the food enzyme laccase from the non‐genetically modified Trametes hirsuta strain AE‐OR
Safety evaluation of an extension of use of the food enzyme laccase from the non‐genetically modified Trametes hirsuta strain AE‐OR Open
The food enzyme laccase (benzenediol:oxygen oxidoreductase, i.e. EC 1.10.3.2) is produced with the non‐genetically modified Trametes hirsuta strain AE‐OR by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in …
View article: Safety evaluation of an extension of use of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐NP
Safety evaluation of an extension of use of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐NP Open
The food enzyme bacillolysin (EC 3.4.24.28) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain AE‐NP by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded tha…
View article: Safety evaluation of an extension of use of the food enzyme glutaminase from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT
Safety evaluation of an extension of use of the food enzyme glutaminase from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT Open
The food enzyme glutaminase (l‐glutamine amidohydrolase; EC 3.5.1.2) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in…
View article: Scientific Guidance on the criteria for the evaluation and on the preparation of applications for the safety assessment of post‐consumer mechanical PET recycling processes intended to be used for manufacture of materials and articles in contact with food
Scientific Guidance on the criteria for the evaluation and on the preparation of applications for the safety assessment of post‐consumer mechanical PET recycling processes intended to be used for manufacture of materials and articles in contact with food Open
In the context of entry into force of Regulation (EU) 2022/1616, EFSA updated the scientific guidance to assist applicants in the preparation of applications for the authorisation or for the modification of an existing authorisation of a ‘…
View article: Safety assessment of the process KGL, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials
Safety assessment of the process KGL, based on the EREMA Basic technology, used to recycle post‐consumer PET into food contact materials Open
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process KGL (EU register number RECYC326), which uses the EREMA Basic technology. The input material is hot caustic washed and…
View article: Safety assessment of the process Fucine Film, based on the Reifenhäuser technology, used to recycle post‐consumer PET into food contact materials
Safety assessment of the process Fucine Film, based on the Reifenhäuser technology, used to recycle post‐consumer PET into food contact materials Open
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process Fucine Film (EU register number RECYC322), which uses the Reifenhäuser technology. The input material consists of hot …
View article: Safety evaluation of an extension of use of the food enzyme α‐amylase from the non‐genetically modified Bacillus licheniformis strain AE‐TA
Safety evaluation of an extension of use of the food enzyme α‐amylase from the non‐genetically modified Bacillus licheniformis strain AE‐TA Open
The food enzyme α‐amylase (4‐α‐d‐glucan glucanohydrolase; EC 3.2.1.1) is produced with the non‐genetically modified microorganism Bacillus licheniformis strain AE‐TA by Amano Enzyme Inc. A safety evaluation of this food enzyme was made pre…
View article: Safety evaluation of the food enzyme triacylglycerol lipase from the non‐genetically modified Penicillium caseifulvum strain AE‐LRF
Safety evaluation of the food enzyme triacylglycerol lipase from the non‐genetically modified Penicillium caseifulvum strain AE‐LRF Open
The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.3) is produced with the non‐genetically modified Penicillium caseifulvum strain AE‐LRF by Amano Enzyme Inc. The food enzyme was free from viable cells of the p…
View article: Safety evaluation of the food enzyme 3‐phytase from the non‐genetically modified Aspergillus niger strain PHY93‐08
Safety evaluation of the food enzyme 3‐phytase from the non‐genetically modified Aspergillus niger strain PHY93‐08 Open
The food enzyme 3‐phytase (myo‐inositol‐hexakisphosphate 3‐phosphohydrolase EC 3.1.3.8) is produced with the non‐genetically modified Aspergillus niger strain PHY93‐08 by Shin Nihon Chemical Co., Ltd. The food enzyme is free from viable ce…
View article: Assessment of Mycotoxin Exposure and Associated Risk in Pregnant Dutch Women: The Human Biomonitoring Approach
Assessment of Mycotoxin Exposure and Associated Risk in Pregnant Dutch Women: The Human Biomonitoring Approach Open
Mycotoxins are toxic secondary metabolites produced by various fungi that can contaminate food crops, which, in turn, may lead to human exposure. Chronic exposure to mycotoxins can cause adverse health effects including reproductive and de…
View article: Safety evaluation of the food enzyme sucrose phosphorylase from the genetically modified Escherichia coli strain LE1B109‐pPB129
Safety evaluation of the food enzyme sucrose phosphorylase from the genetically modified Escherichia coli strain LE1B109‐pPB129 Open
The food enzyme sucrose phosphorylase (sucrose: phosphate α- d-glucosyltransferase; EC 2.4.1.7) is produced with the genetically modified Escherichia coli strain LE1B109-pPB129 by c-LEcta GmbH. The genetic modifications do no…
View article: Safety evaluation of a food enzyme containing bacillolysin and subtilisin activities from the non‐genetically modified Bacillus amyloliquefaciens strain AR‐383
Safety evaluation of a food enzyme containing bacillolysin and subtilisin activities from the non‐genetically modified Bacillus amyloliquefaciens strain AR‐383 Open
The food enzyme with two declared activities, bacillolysin (EC 3.4.24.28) and subtilisin (EC 3.4.21.62), is produced with the non-genetically modified Bacillus amyloliquefaciens strain AR-383 by AB Enzymes GmbH. The food enzyme is i…
View article: Safety evaluation of the food enzyme α‐amylase from the non‐genetically modified Bacillus licheniformis strain AE‐TA
Safety evaluation of the food enzyme α‐amylase from the non‐genetically modified Bacillus licheniformis strain AE‐TA Open
The food enzyme α-amylase (4-α-d-glucan glucanohydrolase; EC 3.2.1.1) is produced with the non-genetically modified microorganism Bacillus licheniformis strain AE-TA by Amano Enzyme Inc. The food enzyme is intended to …
View article: Taxonomic identity of the Bacillus licheniformis strains used to produce food enzymes evaluated in published EFSA opinions
Taxonomic identity of the Bacillus licheniformis strains used to produce food enzymes evaluated in published EFSA opinions Open
Bacillus paralicheniformis, a species known to produce the antimicrobial bacitracin, could be misidentified as Bacillus licheniformis, depending on the identification method used. For this reason, the European Commission requ…
View article: Safety evaluation of an extension of use of the food enzyme glucan 1,4‐α‐glucosidase from the non‐genetically modified Rhizopus arrhizus strain AE‐G
Safety evaluation of an extension of use of the food enzyme glucan 1,4‐α‐glucosidase from the non‐genetically modified Rhizopus arrhizus strain AE‐G Open
The food enzyme glucan 1,4-α-glucosidase (4-α-d-glucan glucohydrolase; EC 3.2.1.3) is produced with the non-genetically modified Rhizopus arrhizus strain AE-G by Amano Enzyme Inc. A safety evaluation of this food enzym…
View article: Safety evaluation of the food enzyme cellobiose phosphorylase from the genetically modified Escherichia coli strain LE1B109‐pPB130
Safety evaluation of the food enzyme cellobiose phosphorylase from the genetically modified Escherichia coli strain LE1B109‐pPB130 Open
The food enzyme cellobiose phosphorylase (cellobiose: phosphate α-d-glucosyltransferase; EC 2.4.1.20) is produced with the genetically modified Escherichia coli strain LE1B109-pPB130 by c-LEcta GmbH. The genetic modifications do not…
View article: Safety evaluation of a food enzyme with phospholipase A1 and lysophospholipase activities from the genetically modified Aspergillus niger strain PLN
Safety evaluation of a food enzyme with phospholipase A1 and lysophospholipase activities from the genetically modified Aspergillus niger strain PLN Open
The food enzyme with phospholipase A1 (phosphatidycholine 1-acylhydrolase, EC 3.1.1.32) and lysophospholipase (2-lysophosphatidylcholine acylhydrolase, EC 3.1.1.5) activities is produced with the genetically modified Aspergil…
View article: Safety evaluation of the food enzyme laccase from the non‐genetically modified Trametes hirsuta strain AE‐OR
Safety evaluation of the food enzyme laccase from the non‐genetically modified Trametes hirsuta strain AE‐OR Open
The food enzyme laccase (benzenediol:oxygen oxidoreductase; EC 1.10.3.2) is produced with the non-genetically modified Trametes hirsuta strain AE-OR by Amano Enzyme Inc. The food enzyme is free from viable cells of the production or…
View article: Safety evaluation of the food enzyme inulinase from the non‐genetically modified Aspergillus welwitschiae strain NZYM‐KF
Safety evaluation of the food enzyme inulinase from the non‐genetically modified Aspergillus welwitschiae strain NZYM‐KF Open
The food enzyme inulinase (1-β-d-fructan fructanohydrolase; EC 3.2.1.7) is produced with the non-genetically modified Aspergillus welwitschiae strain NZYM-KF by Novozymes A/S. The food enzyme is free from viable cells of the …
View article: Safety evaluation of an extension of use of the food enzyme β‐amylase from the non‐genetically modified Bacillus flexus strain AE‐BAF
Safety evaluation of an extension of use of the food enzyme β‐amylase from the non‐genetically modified Bacillus flexus strain AE‐BAF Open
The food enzyme β-amylase (4-α-d-glucan maltohydrolase, EC 3.2.1.2) is produced with the non-genetically modified Bacillus flexus strain AE-BAF by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in whi…
View article: Safety evaluation of the food enzyme carboxypeptidase D from the genetically modified Aspergillus oryzae strain NZYM‐MK
Safety evaluation of the food enzyme carboxypeptidase D from the genetically modified Aspergillus oryzae strain NZYM‐MK Open
The food enzyme carboxypeptidase D (EC 3.4.16.6) is produced with the genetically modified Aspergillus oryzae strain NZYM-MK by Novozymes A/S. It is free from viable cells of the production organism and its DNA. The genetic modifica…
View article: Safety evaluation of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐NP
Safety evaluation of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐NP Open
The food enzyme bacillolysin (EC 3.4.24.28) is produced with the non-genetically modified Bacillus amyloliquefaciens strain AE-NP by Amano Enzyme Inc. The production strain meets the requirements for the qualified presumption of saf…